Research groups

GC09 Nutrigenomics. Metabolic Syndrome

The Nutrigenomics. Metabolic Syndrome research group is a consolidated group of IMIBIC, bringing together both basic and clinical researchers in various scientific disciplines, such as medicine, biology, biochemistry, as well as dieticians, nursing, technical and administrative staff. Our research is mainly based on the effect of dietary components on cardiovascular risk through a double approach: the biological actions of the diet on mechanisms and factors related to the development of atherosclerosis (oxidative stress, inflammation, homeostasis or cellular signaling) and Nutrigenetics, through which we investigate how common genetic variants modulate the influence of the diet on different markers such as postprandial metabolism, endothelial function, overweight or glucose metabolism. We are also interested in the use of these strategies in others pathologies such as hypercholesterolemia, thromboembolic disease, as well as in ageing process. These approaches will allow us to modulate the pathological pathways that underlie the development of various chronic diseases (type 2 diabetes mellitus, metabolic syndrome and cardiovascular diseases).

Over the last few years, our group has been developing predictive models for assessing the risk of disease. Specifically, we are developing innovative models to evaluate biological senescence, coronary heart disease treatment choice and miRNAs plasma levels-based model for type 2 diabetes mellitus development. Moreover, due to the complex nature of gene-environment interactions, another important aim of our research is to establish an appropriate dietary therapy in according to the disease, for personalised nutrition.

Our research group is highly motivated toward internationalisation. In fact, we are currently taking part in two international consortiums. POWER2DM, whose objective is to develop individual self-control of diabetes; and FAME, for the identification of new disease biomarkers.

The Principal Investigator (PI) of the group, José López Miranda, is also PI of both CIBER Physiopathology of Obesity and Nutrition (CIBERobn) and the PAIDI CTS-525. Other collaborations include highly competitive research groups both on a national and international level, as well as pharmaceutical companies.

Research Lines

Networks

    CIBERobn - Physiopathology of Obesity and Nutrition

    NUTRIEPIGEN - NutriEpiGen is a working group of Spanish researchers specialized in the area of lifestyle and epigenetics; Funded by the Ministry of Science, Innovation and Universities of Spain (reference AGL 2017-90623-RED)

    PAIDI CTS-525 - Interaction genes and environment

    PAIDI CTS-212 - Nutrition and disease

Keywords

  • atherosclerosis
  • endothelial dysfunction
  • metabolic syndrome
  • type 2 diabetes mellitus
  • mediterranean diet
  • olive oil
  • polyphenols
  • antioxidants
  • inflammation
  • oxidative stress
  • cholesterol
  • gene expression
  • proteomics
  • nutrigenetics
  • nutrigenomics

Projects

PROJECTS IN 2020

Ongoing projects

Regional

José López Miranda; Prevención y tratamiento con Calcifediol del síndrome respiratorio agudo (SARS) inducido por Coronavirus COVID-19. Estudio COVIDIOL.; Funding Agency: FIBICO. FUNDACION PARA LA INVESTIGACIÓN BIOMÉDICA DE CÓRDOBA; Reference: COVID-0011-2020

Elena María Yubero Serrano; Efecto del Consumo de Dos Modelos de Dieta en el Desarrollo de la Nefropatía Diabetica. Estudio Cordioprev-Nediab; Funding Agency: CONSEJERÍA DE SALUD Y FAMILIAS; Reference: PC-0283-2017

Oriol Alberto Rangel Zúñiga; Papel de la célula alfa en el desarrollo de diabetes mellitus tipo 2 en personas de edad avanzada; Funding Agency: FIBICO. FUNDACION PARA LA INVESTIGACIÓN BIOMÉDICA DE CÓRDOBA; Reference: PI-0107-2018-FIB

José López Miranda; Efecto de una dieta mediterránea rica en aceite de oliva en la homeostasis endotelial a través de la modulación del metabolismo de los productos finales de glicación avanzada en pacientes diabéticos con enfermedad coronaria; Funding Agency: CONSEJERÍA DE TRANSFORMACIÓN ECONÓMICA, INDUSTRIA, CONOCIMIENTO Y UNIVERSIDADES; Reference: 1264133-R

Nacional

José López Miranda; Efecto de una dieta mediterránea rica en aceite de oliva virgen sobre la regresión de diabetes mellitus tipo 2 de reciente diagnóstico: Estudio CORDIOPREV-DIRECT; Funding Agency: MINISTERIO DE ASUNTOS ECONÓMICOS Y TRANSFORMACIÓN DIGITAL; Reference: AGL2015-67896-P

Antonio Camargo García; Composición microbiana del intestino como herramientas predictiva del desarrollo de diabetes mellitus tipo 2; Funding Agency: INSTITUTO DE SALUD CARLOS III; Reference: DTS19/00007

Elena María Yubero Serrano; Efectos de dos modelos de dieta cardiovasculables sobre la reducción de los niveles de productos finales de glicación avanzada y su utilidad como marcador de arteriosclerosis carotidea en pacientes con enfermedad coronaria.; Funding Agency: SOCIEDAD ESPAÑOLA DE ARTERIOSCLEROSIS; Reference: FEA2018/01

José López Miranda; Proyecto de Investigación Prof. Dr. Miguel Vilardell; Funding Agency: FUNDACIÓN ESPAÑOLA DE MEDICINA INTERNA; Reference: MVILARDELL_01_2018

Francisco Pérez Jiménez; La Dieta Mediterránea asociada a probióticos mejora la capacidad cognitiva en pacientes con deterioro cognitivo leve modulando el  eje microbiota-intestino-cerebro; Funding Agency: INSTITUTO DE SALUD CARLOS III; Reference: PI16/01777

Yolanda Almadén Peña; Influencia del Metabolismo Mineral sobre la disfunción endotelial en el Sindrome Metabólico y la Aterosclerosis. Modulación por la Dieta Mediterránea; Funding Agency: INSTITUTO DE SALUD CARLOS III; Reference: PI17/01024

Antonio García Ríos; PREDIMED+DM: Efecto de una pérdida de peso con dieta mediterránea hipocalórica y promoción de la actividad física en la prevención de diabetes tipo 2 en personas con síndrome metabólico.; Funding Agency: INSTITUTO DE SALUD CARLOS III; Reference: PI17/01183

Francisco Fuentes Jiménez; Determinación de nuevas variables predictoras de enfermedad coronaria en pacientes asintomáticos con hipercolesterolemia familiar.; Funding Agency: INSTITUTO DE SALUD CARLOS III; Reference: PI17/01320

Elena María Yubero Serrano; Influencia de la obesidad en la evolución de la nefropatía diabética. Consumo de dos modelos de dieta cardiosaludables como estrategia terapéutica en el desarrollo de la enfermedad; Funding Agency: INSTITUTO DE SALUD CARLOS III; Reference: PI18/01822

Antonio Camargo García; Papel de la microbiota intestinal en las diferencias en el desarrollo de enfermedad cardiovascular en función del género; Funding Agency: INSTITUTO DE SALUD CARLOS III; Reference: PI19/00299

José López Miranda; Efecto de dos dietas saludables sobre la funcionalidad de las HDL y su influencia en la incidencia de eventos cardiovasculares mayores en pacientes con enfermedad coronaria; Funding Agency: AGENCIA ESTATAL DE INVESTIGACIÓN; Reference: PID2019-104362RB-I00

International

Francisco Javier Delgado Lista; POWER2DM - Predictive model-based decision support for diabetes patient empowerment; Funding Agency: COMISIÓN EUROPEA; Reference: PHC28-2015-001

José López Miranda; FAME - Fatty Acid Metabolism - Interlinking Diet with Cardiometabolic Health; Funding Agency: MINISTERIO DE ASUNTOS ECONÓMICOS Y TRANSFORMACIÓN DIGITAL; Reference: ERA-HDHL BioNH 2016-001

PROJECTS IN 2019

Ongoing projects

Regional

Yubero Serrano, E.M.  Effect of the Consumption of Two Dietary Models on the Development of Diabetic Nephropathy. Cordiprev-Nediab study. Funding agency: Regional Ministry of Economy, Innovation, Science and Employment (CEICE). Reference: PC-0283-2017.

Roncero Ramos, I. The role of the alpha cell in the development of type 2 diabetes mellitus in the elderly people. Funding Agency: FIBICO. Reference: PI-0107-2018-FIB 

National

Lopez Miranda, J. – Camargo García, A. Effect of a Mediterranean diet rich in virgin olive oil on the risk and incidence of Type 2 Diabetes Mellitus: Cordioprev-direct study. Reference: AGL2015-67896-P

Pérez Jiménez, F. Mediterranean diet associated with probiotics improves the cognitive function in patients with mild cognitive impairment modulating the axis microbiota-gut-brain. Funding agency: National Institute of Health Carlos III (ISCIII). Reference: PI16/01777

Almadén Peña, Y. The influence of the Mineral Metabolism on Endothelial dysfunction in Metabolic Syndrome and Atherosclerosis. Modulation by the Mediterranean diet. Funding agency: National Institute of Health Carlos III (ISCIII). Reference: PI17/01024

García Rios, A. Importance of the selection of stable mutants and of persister variants in the expression of colistin heterorresistance in Klebsiella pneumoniae. Funding agency: National Institute of Health Carlos III (ISCIII). Reference: PI17/01183

Fuentes Jiménez, F. Determination of new predictors of coronary heart disease in asymptomatic patients with familial Hypercholesterolemia. Funding agency: National Institute of Health Carlos III (ISCIII). Reference: PI17/01320.

Lopez Miranda, J and Yubero Serrano, EM. Regression of recently diagnosed type 2 diabetes mellitus: effect of HDL functionality. Research Funding Prof. Dr. Miguel Vilardell. Funding Agency: Fundacion Española De Medicina Interna. Reference: MVILARDELL_01_2018  

Yubero Serrano, E.M. Influence of obesity on the progression of diabetic nephropathy. Consumption of two models of hearthealthy diet as a therapeutic strategy in the development of the disease. Funding agency: National Institute of Health Carlos III (ISCIII). Reference: PI18/01822.

Yubero Serrano, E.M. New biomarkers and therapeutic targets in breast and prostate cancer: molecular  mechanisms in the pathological interaction between obesity and cancer. Funding Agency: Asociación Española Contra el Cáncer. Reference: AECC 2018/01

Camargo García, A. Composición microbiana del intestino como herramienta predictiva del desarrollo de Diabetes Mellitus tipo 2. Funding agency: National Institute of Health Carlos III (ISCIII). Reference: DTS19/00007 

Camargo García, A. Papel de la microbiota intestinal en las diferencias en el desarrollo de enfermedad cardiovascular en función del género Funding agency: National Institute of Health Carlos III (ISCIII). Reference: PI19/00299              

International

Delgado Lista, J. POWER2DM - Predictive model-based decision support for diabetes patient empowerment. Funding Agency: European Commission H2020. Reference: PHC28-2015-001

López Miranda, J. FAME - Fatty Acid Metabolism - Interlinking Diet with Cardiometabolic Health. Funding agency: JPI HDHL: BIOMARKERS FOR NUTRITION AND HEALTH – MINECO 2016. Reference: ERA-HDHL BioNH 2016-001

Publications

Publications in 2020

Camargo A, Vals-Delgado C, Alcala-Diaz JF, Villasanta-Gonzalez A, Gomez-Delgado F, Haro C, Leon-Acuna A, Cardelo MP, Torres-Pena JD, Guler I, Malagon MM, Ordovas JM, Perez-Martinez P, Delgado-Lista J, Lopez-Miranda J. A Diet-Dependent Microbiota Profile Associated with Incident Type 2 Diabetes: From the CORDIOPREV Study. MOLECULAR NUTRITION & FOOD RESEARCH. 2020. 64 (23):- DOI: 10.1002/mnfr.202000730 
IF: 5,309 Q: 1 D: 1

Alvarez MV, Aparicio-Martinez P, Pozo FJF, Alonso JV, Sanchez IMB, Romero-Saldana M. A Sustainable Approach to the Metabolic Syndrome in Children and Its Economic Burden. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH. 2020. 17 (6):- DOI: 10.3390/ijerph17061891 
IF: 2,849 Q: 1

Alvarez-Alvarez I, Toledo E, Lecea O, Salas-Salvado J, Corella D, Buil-Cosiales P, Zomeno MD, Vioque J, Martinez JA, Konieczna J, Baron-Lopez FJ, Lopez-Miranda J, Estruch R, Bueno-Cavanillas A, Alonso-Gomez AM, Tur JA, Tinahones FJ, Serra-Majem L, Martin . Adherence to a priori dietary indexes and baseline prevalence of cardiovascular risk factors in the PREDIMED-Plus randomised trial. EUROPEAN JOURNAL OF NUTRITION. 2020. 59 (3):1219-1232 DOI: 10.1007/s00394-019-01982-x 
IF: 4,664 Q: 1

Bouzas C, Bibiloni MD, Julibert A, Ruiz-Canela M, Salas-Salvado J, Corella D, Zomeno MD, Romaguera D, Vioque J, Alonso-Gomez AM, Warnberg J, Martinez JA, Serra-Majem L, Estruch R, Tinahones FJ, Lapetra J, Pinto X, Rios AG, Bueno-Cavanillas A, Gaforio JJ, . Adherence to the Mediterranean Lifestyle and Desired Body Weight Loss in a Mediterranean Adult Population with Overweight: A PREDIMED-Plus Study. NUTRIENTS. 2020. 12 (7):- DOI: 10.3390/nu12072114 
IF: 4,546 Q: 1

Guzman-Ruiz R, Tercero-Alcazar C, Rabanal-Ruiz Y, Diaz-Ruiz A, El Bekay R, Rangel-Zuniga OA, Navarro-Ruiz MC, Molero L, Membrives A, Ruiz-Rabelo JF, Pandit A, Lopez-Miranda J, Tinahones FJ, Malagon MM. Adipose tissue depot-specific intracellular and extracellular cues contributing to insulin resistance in obese individuals. FASEB JOURNAL. 2020. 34 (6):7520-7539 DOI: 10.1096/fj.201902703R 
IF: 4,966 Q: 1 D: 1

Yubero-Serrano EM, Perez-Martinez P. Advanced Glycation End Products and Their Involvement in Cardiovascular Disease. ANGIOLOGY. 2020. 71 (8):698-700 DOI: 10.1177/0003319720916301 
IF: 2,255 Q: 3

Gutierrez-Mariscal FM, Garcia-Rios A, Gomez-Luna P, Fernandez-Gandara C, Cardelo MP, de la Cruz-Ares S, Rodriguez-Cantalejo F, Luque RM, Leon-Acuna A, Delgado-Lista J, Perez-Martinez P, Yubero-Serrano EM, Lopez-Miranda J. Age-dependent effect of metabolic phenotypes on carotid atherosclerotic disease in coronary heart disease patients (CORDIOPREV study). BMC GERIATRICS. 2020. 20 (1):- DOI: 10.1186/s12877-020-01544-5 
IF: 3,077 Q: 1

Mena-Sanchez G, Babio N, Becerra-Tomas N, Martinez-Gonzalez MA, Diaz-Lopez A, Corella D, Zomeno MD, Romaguera D, Vioque J, Alonso-Gomez AM, Warnberg J, Martinez JA, Serra-Majem L, Estruch R, Bernal R, Lapetra J, Pinto X, Tur JA, Lopez-Miranda J, Cano-Iban. Association between dairy product consumption and hyperuricemia in an elderly population with metabolic syndrome. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES. 2020. 30 (2):214-222 DOI: 10.1016/j.numecd.2019.09.023 
IF: 3,72 Q: 3

Fernandez-Garcia JC, Munoz-Garach A, Martinez-Gonzalez MA, Salas-Salvado J, Corella D, Hernaez A, Romaguera D, Vioque J, Alonso-Gomez AM, Warnberg J, Martinez JA, Serra-Majem L, Estruch R, Lapetra J, Pinto X, Tur JA, Garcia-Rios A, Molina LG, Gaforio JJ, . Association Between Lifestyle and Hypertriglyceridemic Waist Phenotype in the PREDIMED-Plus Study. OBESITY. 2020. 28 (3):537-543 DOI: 10.1002/oby.22728 
IF: 3,742 Q: 2

Rodilla E, Saura A, Jimenez I, Mendizabal A, Pineda-Cantero A, Lorenzo-Hernandez E, Fidalgo-Montero MD, Lopez-Cuervo JF, Gil-Sanchez R, Rabadan-Pejenaute E, Abella-Vazquez L, Giner-Galvan V, Solis-Marquinez MN, Boixeda R, Pena-Fernandez AD, Carrasco-Sanchez FJ, Gonzalez-Moraleja J, Torres-Pena JD, Guisado-Espartero ME, Escobar-Sevilla J, Guzman-Garcia M, Martin-Escalante MD, Martinez-Gonzalez AL, Casas-Rojo JM, Gomez-Huelgas R. Association of Hypertension with All-Cause Mortality among Hospitalized Patients with COVID-19. JOURNAL OF CLINICAL MEDICINE. 2020. 9 (10):- DOI: 10.3390/jcm9103136 
IF: 3,303 Q: 1

Ortiz-Morales AM, Alcala-Diaz JF, Rangel-Zuniga OA, Corina A, Quintana-Navarro G, Cardelo MP, Yubero-Serrano E, Malagon MM, Delgado-Lista J, Ordovas JM, Lopez-Miranda J, Perez-Martinez P. Biological senescence risk score. A practical tool to predict biological senescence status. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 2020. 50 (11):- DOI: 10.1111/eci.13305 
IF: 3,481 Q: 1

Martinez-Gonzalez MA, Fernandez-Lazaro CI, Toledo E, Diaz-Lopez A, Corella D, Goday A, Romaguera D, Vioque J, Alonso-Gomez AM, Warnberg J, Martinez JA, Serra-Majem L, Estruch R, Tinahones FJ, Lapetra J, Pinto X, Tur JA, Lopez-Miranda J, Cano-Ibanez N, Del. Carbohydrate quality changes and concurrent changes in cardiovascular risk factors: a longitudinal analysis in the PREDIMED-Plus randomized trial. AMERICAN JOURNAL OF CLINICAL NUTRITION. 2020. 111 (2):291-306 DOI: 10.1093/ajcn/nqz298 
IF: 6,766 Q: 1 D: 1

de Larriva APA, Limia-Perez L, Alcala-Diaz JF, Alonso A, Lopez-Miranda J, Delgado-Lista J. Ceruloplasmin and Coronary Heart Disease-A Systematic Review. NUTRIENTS. 2020. 12 (10):- DOI: 10.3390/nu12103219 
IF: 4,546 Q: 1

Elgendy IY, Fogerty A, Blanco-Molina A, Rosa V, Schellong S, Skride A, Portillo J, Lopez-Miguel P, Monreal M, Weinberg I. Clinical Characteristics and Outcomes of Women Presenting with Venous Thromboembolism during Pregnancy and Postpartum Period: Findings from the RIETE Registry. THROMBOSIS AND HAEMOSTASIS. 2020. 120 (10):1454-1462 DOI: 10.1055/s-0040-1714211 
IF: 4,379 Q: 1

Casas-Rojo JM, Anton-Santos JM, Millan-Nunez-Cortes J, Lumbreras-Bermejo C, Ramos-Rincon JM, Roy-Vallejo E, Artero-Mora A, Arnalich-Fernandez F, Garcia-Brunen JM, Vargas-Nunez JA, Freire-Castro S, Manzano-Espinosa L, Perales-Fraile I, Crestelo-Vieitez A, Puchades-Gimeno F, Rodilla-Sala E, Solis-Marquinez MN, Bonet-Tur D, Fidalgo-Moreno MP, Fonseca-Aizpuru EM, Carrasco-Sanchez FJ, Rabadan-Pejenaute E, Rubio-Rivas M, Torres-Pena JD, Gomez-Huelgas R. Clinical characteristics of patients hospitalized with COVID-19 in Spain: Results from the SEMI-COVID-19 Registry. REVISTA CLINICA ESPANOLA. 2020. 220 (8):480-494 DOI: 10.1016/j.rce.2020.07.003 
IF: 1,304 Q: 3

Gutierrez-Mariscal FM, Arenas-de Larriva AP, Limia-Perez L, Romero-Cabrera JL, Yubero-Serrano EM, Lopez-Miranda J. Coenzyme Q(10) Supplementation for the Reduction of Oxidative Stress: Clinical Implications in the Treatment of Chronic Diseases. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2020. 21 (21):- DOI: 10.3390/ijms21217870 
IF: 4,556 Q: 1

Arevalo-Lorido JC, Carretero-Gomez J, Gomez-Huelgas R, Llacer P, Manzano L, Simon MAQ, Villanueva BR, Franco AG, Cepeda JM, Perez-Barquero MM. Comorbidities and their implications in patients with and without type 2 diabetes mellitus and heart failure with preserved ejection fraction. Findings from the rica registry. INTERNATIONAL JOURNAL OF CLINICAL PRACTICE. . 75 (1):- DOI: 10.1111/ijcp.13661 
IF: 2,444 Q: 2

Lorido JCA, Gomez JC, Huelgas RG, Lopez RQ, Ramos MFD, Iglesias AS, Laiglesia FR, Franco AG, Rodrigo JMC, Montero-Perez-Barquero M. Comorbidity in patients with type 2 diabetes mellitus and heart failure with preserved ejection fraction. Cluster analysis of the RICA registry. Opportunities for improvement. REVISTA CLINICA ESPANOLA. 2020. 220 (7):409-416 DOI: 10.1016/j.rce.2019.10.001 
IF: 1,304 Q: 3

Castillo-Mayen R, Cano-Espejo C, Luque B, Cuadrado E, Gutierrez-Domingo T, Arenas A, Rubio SJ, Delgado-Lista J, Perez-Martinez P, Tabernero C. Influence of Self-Efficacy and Motivation to Follow a Healthy Diet on Life Satisfaction of Patients with Cardiovascular Disease: A Longitudinal Study. NUTRIENTS. 2020. 12 (7):- DOI: 10.3390/nu12071903 
IF: 4,546 Q: 1

Becerra-Tomas N, Mena-Sanchez G, Diaz-Lopez A, Martinez-Gonzalez MA, Babio N, Corella D, Freixer G, Romaguera D, Vioque J, Alonso-Gomez AM, Warnberg J, Martinez JA, Serra-Majem L, Estruch R, Fernandez-Garcia JC, Lapetra J, Pinto X, Tur JA, Lopez-Miranda J. Cross-sectional association between non-soy legume consumption, serum uric acid and hyperuricemia: the PREDIMED-Plus study. EUROPEAN JOURNAL OF NUTRITION. 2020. 59 (5):2195-2206 DOI: 10.1007/s00394-019-02070-w 
IF: 4,664 Q: 1

Lopez-Bascon MA, Calderon-Santiago M, Diaz-Lozano A, Camargo A, Lopez-Miranda J, Priego-Capote F. Development of a qualitative/quantitative strategy for comprehensive determination of polar lipids by LC-MS/MS in human plasma. ANALYTICAL AND BIOANALYTICAL CHEMISTRY. 2020. 412 (2):489-498 DOI: 10.1007/s00216-019-02261-8 
IF: 3,637 Q: 1

Vaquero-Alvarez M, Molina-Luque R, Fonseca-Pozo FJ, Molina-Recio G, Lopez-Miranda J, Romero-Saldana M. Diagnostic Precision of Anthropometric Variables for the Detection of Hypertension in Children and Adolescents. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH. 2020. 17 (12):- DOI: 10.3390/ijerph17124415 
IF: 2,849 Q: 1

Cano-Ibanez N, Gea A, Ruiz-Canela M, Corella D, Salas-Salvado J, Schroder H, Navarrete-Munoz EM, Romaguera D, Martinez JA, Baron-Lopez FJ, Lopez-Miranda J, Estruch R, Riquelme-Gallego B, Alonso-Gomez A, Tur JA, Tinahones FJ, Serra-Majem L, Martin V, Lapet. Diet quality and nutrient density in subjects with metabolic syndrome: Influence of socioeconomic status and lifestyle factors. A cross-sectional assessment in the PREDIMED-Plus study. CLINICAL NUTRITION. 2020. 39 (4):1161-1173 DOI: 10.1016/j.clnu.2019.04.032 
IF: 6,36 Q: 1

del Rio-Moreno M, Luque RM, Rangel-Zuniga OA, Alors-Perez E, Alcala-Diaz JF, Roncero-Ramos I, Camargo A, Gahete MD, Lopez-Miranda J, Castano JP. Dietary Intervention Modulates the Expression of Splicing Machinery in Cardiovascular Patients at High Risk of Type 2 Diabetes Development: From the CORDIOPREV Study. NUTRIENTS. 2020. 12 (11):- DOI: 10.3390/nu12113528 
IF: 4,546 Q: 1

Castro-Barquero S, Tresserra-Rimbau A, Vitelli-Storelli F, Domenech M, Salas-Salvado J, Martin-Sanchez V, Rubin-Garcia M, Buil-Cosiales P, Corella D, Fito M, Romaguera D, Vioque J, Alonso-Gomez AM, Warnberg J, Martinez JA, Serra-Majem L, Tinahones FJ, Lap. Dietary Polyphenol Intake is Associated with HDL-Cholesterol and A Better Profile of other Components of the Metabolic Syndrome: A PREDIMED-Plus Sub-Study. NUTRIENTS. 2020. 12 (3):- DOI: 10.3390/nu12030689 
IF: 4,546 Q: 1

Bouzas C, Bibiloni MD, Garcia S, Mateos D, Martinez-Gonzalez MA, Salas-Salvado J, Corella D, Schroder H, Martinez JA, Alonso-Gomez AM, Warnberg J, Vioque J, Romaguera D, Lopez-Miranda J, Estruch R, Tinahones FJ, Lapetra J, Serra-Majem L, Bueno-Cavanillas A, Mico-Perez RM, Pinto X, Delgado-Rodriguez M, Ortiz-Ramos M, Altes-Boronat A, Luca BL, Daimiel L, Ros E, Sayon-Orea C, Becerra-Tomas N, Gimenez-Alba IM, Castaner O, Abete I, Tojal-Sierra L, Perez-Lopez J, Bernabe-Casanova A, Martin-Padillo M, Garcia-Rios A, Castro-Barquero S, Fernandez-Garcia JC, Santos-Lozano JM, Fernandez-Lazaro CI, Hernandez-Alonso P, Saiz C, Zomeno MD, Zulet MA, Bello-Mora MC, Basterra-Gortari FJ, Canudas S, Goday A, Tur JA. Dietary Quality Changes According to the Preceding Maximum Weight: A Longitudinal Analysis in the PREDIMED-Plus Randomized Trial. NUTRIENTS. 2020. 12 (10):- DOI: 10.3390/nu12103023 
IF: 4,546 Q: 1

Huerta-Preciado J, Franco J, Formiga F, Iborra PL, Epelde F, Franco AG, Ormaechea G, Manzano L, Cepeda-Rodrigo JM, Montero-Perez-Barquero M, Rocha PA, Anarte L, Arevalo-Lorido JC, Cabanes Y, Carrascosa S, Izquierdo MC, Cepeda JM, Cerqueiro JM, Martel AC, Epelde F, Formiga F, Vanegas JF, Escriva DG, Franco AG, Leon A, Llacer P, Lopez-Castellanos G, Furio OL, Manzano L, Montero-Perez-Barquero M. . Differential characteristics of acute heart failure in very elderly patients: the prospective RICA study. AGING CLINICAL AND EXPERIMENTAL RESEARCH. 2020. 32 (9):1789-1799 DOI: 10.1007/s40520-019-01363-8 
IF: 2,697 Q: 3

Jimenez-Vacas JM, Herrero-Aguayo V, Montero-Hidalgo AJ, Gomez-Gomez E, Fuentes-Fayos AC, Leon-Gonzalez AJ, Saez-Martinez P, Alors-Perez E, Pedraza-Arevalo S, Gonzalez-Serrano T, Reyes O, Martinez-Lopez A, Sanchez-Sanchez R, Ventura S, Yubero-Serrano EM, R. Dysregulation of the splicing machinery is directly associated to aggressiveness of prostate cancer. EBIOMEDICINE. 2020. 51 ():- DOI: 10.1016/j.ebiom.2019.11.008 
IF: 5,736 Q: 1

Castillo ME, Costa LME, Barrios JMV, Diaz JFA, Miranda JL, Bouillon R, Gomez JMQ. Effect of calcifediol treatment and best available therapy versus best available therapy on intensive care unit admission and mortality among patients hospitalized for COVID-19: A pilot randomized clinical study. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2020. 203 ():- DOI: 10.1016/j.jsbmb.2020.105751 
IF: 3,813 Q: 2

Cano-Ibañez N, Bueno-Cavanillas A, Martinez-Gonzalez MA, Salas-Salvado J, Corella D, Freixer GL, Romaguera D, Vioque J, Alonso-Gomez AM, Warnberg J, Martinez JA, Serra-Majem L, Estruch R, Tinahones FJ, Lapetra J, Pinto X, Tur JA, Garcia-Rios A, Garcia-Mol. Effect of changes in adherence to Mediterranean diet on nutrient density after 1-year of follow-up: results from the PREDIMED-Plus Study. EUROPEAN JOURNAL OF NUTRITION. 2020. 59 (6):2395-2409 DOI: 10.1007/s00394-019-02087-1 
IF: 4,664 Q: 1

de la Cruz-Ares S, Cardelo MP, Gutierrez-Mariscal FM, Torres-Pena JD, Garcia-Rios A, Katsiki N, Malagon MM, Lopez-Miranda J, Perez-Martinez P, Yubero-Serrano EM. Endothelial Dysfunction and Advanced Glycation End Products in Patients with Newly Diagnosed Versus Established Diabetes: From the CORDIOPREV Study. NUTRIENTS. 2020. 12 (1):- DOI: 10.3390/nu12010238 
IF: 4,546 Q: 1

Rodriguez-Ortiz ME, Alcala-Diaz JF, Canalejo A, Torres-Pena JD, Gomez-Delgado F, Munoz-Castaneda JR, Delgado-Lista J, Rodriguez M, Lopez-Miranda J, Almaden Y. Fibroblast growth factor 23 predicts carotid atherosclerosis in individuals without kidney disease. The CORDIOPREV study. EUROPEAN JOURNAL OF INTERNAL MEDICINE. 2020. 74 ():79-85 DOI: 10.1016/j.ejim.2019.12.008 
IF: 4,329 Q: 1

Catoi AF, Corina A, Katsiki N, Vodnar DC, Andreicut AD, Stoian AP, Rizzo M, Perez-Martinez P. Gut microbiota and aging-A focus on centenarians. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. 2020. 1866 (7):- DOI: 10.1016/j.bbadis.2020.165765 
IF: 4,352 Q: 1

Papandreou C, Bullo M, Diaz-Lopez A, Martinez-Gonzalez MA, Corella D, Castaner O, Vioque J, Romaguera D, Martinez AJ, Perez-Farinos N, Lopez-Miranda J, Estruch R, Bueno-Cavanillas A, Alonso-Gomez A, Tur JA, Tinahones FJ, Serra-Majem L, Martin V, Lapetra J. High sleep variability predicts a blunted weight loss response and short sleep duration a reduced decrease in waist circumference in the PREDIMED-Plus Trial. INTERNATIONAL JOURNAL OF OBESITY. 2020. 44 (2):330-339 DOI: 10.1038/s41366-019-0401-5 
IF: 4,419 Q: 1

de Isla LP, Arroyo-Olivares R, Alonso R, Muniz-Grijalvo O, Diaz-Diaz JL, Zambon D, Fuentes F, Mata N, Piedecausa M, Manas MD, Munoz-Torrero JFS, Miramontes-Gonzalez JP, de Andres R, Mauri M, Aguado R, Brea A, Cepeda JM, Vidal-Pardo JI, Martinez-Faedo C, Barba MA, Argueso R, Ruiz-Perez E, Michan A, Arrieta F, Fernandez MR, Perez L, Pinilla JM, Diaz-Soto G, Pinto X, Padro T, Badimon L, Mata P. Incidence of cardiovascular events and changes in the estimated risk and treatment of familial hypercholesterolemia: the SAFEHEART registry. REVISTA ESPANOLA DE CARDIOLOGIA. 2020. 73 (10):828-834 DOI: 10.1016/j.recesp.2019.10.013 
IF: 4,642 Q: 1

Tufano A, Lopez-Jimenez L, Bikdeli B, Garcia-Bragado F, Mazzolai L, Amitrano M, Gomez-Cuervo C, Marchena PJ, Madridano O, Monreal M, Di Micco P. Inferior vena cava agenesis in patients with lower limb deep vein thrombosis in the RIETE registry. When and why to suspect. INTERNATIONAL JOURNAL OF CARDIOLOGY. 2020. 305 ():115-119 DOI: 10.1016/j.ijcard.2020.01.013 
IF: 3,229 Q: 2

Rodriguez-Ortiz ME, Diaz-Tocados JM, Munoz-Castaneda JR, Herencia C, Pineda C, Martinez-Moreno JM, de Oca AM, Lopez-Baltanas R, Alcala-Diaz J, Ortiz A, Aguilera-Tejero E, Felsenfeld A, Rodriguez M, Almaden Y. Inflammation both increases and causes resistance to FGF23 in normal and uremic rats. CLINICAL SCIENCE. 2020. 134 (1):15-32 DOI: 10.1042/CS20190779 
IF: 5,223 Q: 1

Santos-Marcos JA, Barroso A, Rangel-Zuniga OA, Perdices-Lopez C, Haro C, Sanchez-Garrido MA, Molina-Abril H, Ohisson C, Perez-Martinez P, Poutanen M, Lopez-Miranda J, Perez-Jimenez F, Tena-Sempere M, Camargo A. Interplay between gonadal hormones and postnatal overfeeding in defining sex-dependent differences in gut microbiota architecture. AGING-US. 2020. 12 (20):19979-20000 DOI: 10.18632/aging.104140 
IF: 4,831 Q: 1

Minarro JC, Zamorano-Moyano C, Urbano-Luque MT, Arenas-de Larriva AP, Izquierdo-Fernandez A, Quevedo-Reinoso R. Is COVID-19 affecting the incidence of hip fractures?. INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED. 2020. 51 (10):2329-2329 DOI: 10.1016/j.injury.2020.07.018 
IF: 2,106 Q: 2

Perez-Martinez P, Gomez-Huelgas R, Perez-Jimenez F. Is the planetary health diet the solution for mitigating noncommunicable diseases?. REVISTA CLINICA ESPANOLA. 2020. 220 (9):573-575 DOI: 10.1016/j.rce.2019.12.004 
IF: 1,304 Q: 3

Gallardo-Alfaro L, Bibiloni MDM, Mascaro CM, Montemayor S, Ruiz-Canela M, Salas-Salvado J, Corella D, Fito M, Romaguera D, Vioque J, Alonso-Gomez AM, Warnberg J, Martinez JA, Serra-Majem L, Estruch R, Fernandez-Garcia JC, Lapetra J, Pinto X, Garcia Rios A. Leisure-Time Physical Activity, Sedentary Behaviour and Diet Quality are Associated with Metabolic Syndrome Severity: The PREDIMED-Plus Study. NUTRIENTS. 2020. 12 (4):1013- DOI: 10.3390/nu12041013 
IF: 4,546 Q: 1

Quintana-Navarro GM, Alcala-Diaz JF, Lopez-Moreno J, Perez-Corral I, Leon-Acuna A, Torres-Pena JD, Rangel-Zuniga OA, de Larriva APA, Corina A, Camargo A, Yubero-Serrano EM, Rodriguez-Cantalejo F, Garcia-Rios A, Luque RM, Ordovas JM, Perez-Martinez P, Lope. Long-term dietary adherence and changes in dietary intake in coronary patients after intervention with a Mediterranean diet or a low-fat diet: the CORDIOPREV randomized trial. EUROPEAN JOURNAL OF NUTRITION. 2020. 59 (5):2099-2110 DOI: 10.1007/s00394-019-02059-5 
IF: 4,664 Q: 1

Yubero-Serrano EM, Fernandez-Gandara C, Garcia-Rios A, Rangel-Zuniga OA, Gutierrez-Mariscal FM, Torres-Pena JD, Marin C, Lopez-Moreno J, Castano JP, Delgado-Lista J, Ordovas JM, Perez-Martinez P, Lopez-Miranda J. Mediterranean diet and endothelial function in patients with coronary heart disease: An analysis of the CORDIOPREV randomized controlled trial. PLOS MEDICINE. 2020. 17 (9):- DOI: 10.1371/journal.pmed.1003282 
IF: 10,1 Q: 1 D: 1

Torres-Pena JD, Rangel-Zuniga OA, Alcala-Diaz JF, Lopez-Miranda J, Delgado-Lista J. Mediterranean Diet and Endothelial Function: A Review of its Effects at Different Vascular Bed Levels. NUTRIENTS. 2020. 12 (8):- DOI: 10.3390/nu12082212 
IF: 4,546 Q: 1

Julibert A, Bibiloni MD, Gallardo-Alfaro L, Abbate M, Martinez-Gonzalez MA, Salas-Salvado J, Corella D, Fito M, Martinez JA, Alonso-Gomez AM, Warnberg J, Vioque J, Romaguera D, Lopez-Miranda J, Estruch R, Tinahones FJ, Lapetra J, Serra-Majem L, Cano-Ibanez N, Martin-Sanchez V, Pinto X, Gaforio JJ, Matia-Martin P, Vidal J, Vazquez C, Daimiel L, Ros E, Sayon-Orea C, Becerra-Tomas N, Gimenez-Alba IM, Castaner O, Abete I, Tojal-Sierra L, Perez-Lopez J, Notario-Barandiaran L, Colom A, Garcia-Rios A, Castro-Barquero S, Bernal R, Santos-Lozano JM, Fernandez-Lazaro CI, Hernandez-Alonso P, Saiz C, Zomeno MD, Zulet MA, Bello-Mora MC, Basterra-Gortari J, Canudas S, Goday A, Tur JA. Metabolic Syndrome Features and Excess Weight Were Inversely Associated with Nut Consumption after 1-Year Follow-Up in the PREDIMED-Plus Study. JOURNAL OF NUTRITION. 2020. 150 (12):3161-3170 DOI: 10.1093/jn/nxaa289 
IF: 4,281 Q: 1

Perez-Belmonte LM, Torres-Pena JD, Lopez-Carmona MD, Ayala-Gutierrez MM, Fuentes-Jimenez F, Huerta LJ, Munoz JA, Rubio-Rivas M, Madrazo M, Garcia MG, Montes BV, Sola JF, Ena J, Ferrer RG, Perez CM, Ripper CJ, Lecumberri JJN, Acedo IE, Canteli SP, Cosio SF, Martinez FA, Rodriguez BC, Perez-Martinez P, Ramos-Rincon JM, Gomez-Huelgas R. Mortality and other adverse outcomes in patients with type 2 diabetes mellitus admitted for COVID-19 in association with glucose-lowering drugs: a nationwide cohort study. BMC MEDICINE. 2020. 18 (1):- DOI: 10.1186/s12916-020-01832-2 
IF: 6,782 Q: 1 D: 1

Luque B, Castillo-Mayen R, Cuadrado E, Gutierrez-Domingo T, Rubio SJ, Arenas A, Delgado-Lista J, Martinez PP, Tabernero C. The Role of Emotional Regulation and Affective Balance on Health Perception in Cardiovascular Disease Patients According to Sex Differences. JOURNAL OF CLINICAL MEDICINE. 2020. 9 (10):- DOI: 10.3390/jcm9103165 
IF: 3,303 Q: 1

Barroso A, Santos-Marcos JA, Perdices-Lopez C, Vega-Rojas A, Sanchez-Garrido MA, Krylova Y, Molina-Abril H, Ohlsson C, Perez-Martinez P, Poutanen M, Lopez-Miranda J, Tena-Sempere M, Camargo, A. Neonatal exposure to androgens dynamically alters gut microbiota architecture. JOURNAL OF ENDOCRINOLOGY. 2020. 247 (1):69-85 DOI: 10.1530/JOE-20-0277 
IF: 4,041 Q: 2

Stefil M, Manzano L, Montero-Perez-Barquero M, Coats AJS, Flather M. New horizons in management of heart failure in older patients. AGE AND AGEING. 2020. 49 (1):16-19 DOI: 10.1093/ageing/afz122 
IF: 4,902 Q: 1

Bibiloni MD, Bouzas C, Abbate M, Martinez-Gonzalez MA, Corella D, Salas-Salvado J, Zomeno MD, Vioque J, Romaguera D, Martinez JA, Warnberg J, Lopez-Miranda J, Estruch R, Bueno-Cavanillas A, Alonso-Gomez A, Tinahones F, Serra-Majem L, Martin V, Lapetra J, . Nutrient adequacy and diet quality in a Mediterranean population with metabolic syndrome: A cross-sectional study. CLINICAL NUTRITION. 2020. 39 (3):853-861 DOI: 10.1016/j.clnu.2019.03.018 
IF: 6,36 Q: 1

Quezada A, Jimenez D, Bikdeli B, Muriel A, Aramberri M, Lopez-Jimenez L, Sahuquillo JC, Otero R, Porfidia A, Monreal M. Outcomes after Vena Cava Filter Use in Patients with Cancer-Associated Venous Thromboembolism and Contraindications to Anticoagulation. THROMBOSIS AND HAEMOSTASIS. 2020. 120 (7):1035-1044 DOI: 10.1055/s-0040-1710589 
IF: 4,379 Q: 1

Pedro-Botet J, Lopez-Miranda J, Badimon L, Civeira F, Guijarro C, Millan J, Mostaza JM, Pinto X, Valdivielso P, Masana L. Overall Mortality and LDL Cholesterol Reduction in Secondary Prevention Trials of Cardiovascular Disease. AMERICAN JOURNAL OF CARDIOVASCULAR DRUGS. 2020. 20 (4):325-332 DOI: 10.1007/s40256-019-00376-y 
IF: 2,674 Q: 2

Mehdipoor G, Jimenez D, Bertoletti L, Fidalgo A, Munoz-Torrero JFS, Gonzalez-Martinez JP, Blanco-Molina A, Aibar MA, Bonnefoy PB, Khorasani R, Prince MR, Bikdeli B, Monreal M. Patient-Level, Institutional, and Temporal Variations in Use of Imaging Modalities to Confirm Pulmonary Embolism. CIRCULATION-CARDIOVASCULAR IMAGING. 2020. 13 (5):- DOI: 10.1161/CIRCIMAGING.120.010651 
IF: 5,691 Q: 1 D: 1

Daimiel L, Martinez-Gonzalez MA, Corella D, Salas-Salvado J, Schroder H, Vioque J, Romaguera D, Martinez JA, Warnberg J, Lopez-Miranda J, Estruch R, Cano-Ibanez N, Alonso-Gomez A, Tur JA, Tinahones FJ, Serra-Majem L, Mico-Perez RM, Lapetra J, Galdon A, Pi. Physical fitness and physical activity association with cognitive function and quality of life: baseline cross-sectional analysis of the PREDIMED-Plus trial. SCIENTIFIC REPORTS. 2020. 10 (1):- DOI: 10.1038/s41598-020-59458-6 
IF: 3,998 Q: 1

Pozuelo-Sanchez I, Villasanta-Gonzalez A, Alcala-Diaz JF, Vals-Delgado C, Leon-Acuna A, Gonzalez-Requero A, Yubero-Serrano EM, Luque RM, Caballero-Villarraso J, Quesada I, Ordovas JM, Perez-Martinez P, Roncero-Ramos I, Lopez-Miranda J. Postprandial Lipemia Modulates Pancreatic Alpha-Cell Function in the Prediction of Type 2 Diabetes Development: The CORDIOPREV Study. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. 2020. 68 (5):1266-1275 DOI: 10.1021/acs.jafc.9b06801 
IF: 4,192 Q: 1 D: 1

Roncero-Ramos I, Alcala-Diaz JF, Rangel-Zuniga OA, Gomez-Delgado F, Jimenez-Lucena R, Garcia-Rios A, Vals-Delgado C, Romero-Baldonado C, Luque RM, Ordovas JM, Perez-Martinez P, Camargo A, Lopez-Miranda J. Prediabetes diagnosis criteria, type 2 diabetes risk and dietary modulation: The CORDIOPREV study. CLINICAL NUTRITION. 2020. 39 (2):492-500 DOI: 10.1016/j.clnu.2019.02.027 
IF: 6,36 Q: 1

Gutierrez-Mariscal FM, Cardelo MP, de la Cruz S, Alcala-Diaz JF, Roncero-Ramos I, Guler I, Vals-Delgado C, Lopez-Moreno A, Luque RM, Delgado-Lista J, Perez-Martinez P, Yubero-Serrano EM, Lopez-Miranda J. Reduction in Circulating Advanced Glycation End Products by Mediterranean Diet Is Associated with Increased Likelihood of Type 2 Diabetes Remission in Patients with Coronary Heart Disease: From the Cordioprev Study. MOLECULAR NUTRITION & FOOD RESEARCH. 2021. 65 (1):- DOI: 10.1002/mnfr.201901290 
IF: 5,309 Q: 1 D: 1

Sanchez-Quesada C, Toledo E, Gonzalez-Mata G, Ramos-Ballesta MI, Peis JI, Martinez-Gonzalez MA, Salas-Salvado J, Corella D, Fito M, Romaguera D, Vioque J, Alonso-Gomez AM, Warnberg J, Martinez JA, Serra-Majem L, Estruch R, Tinahones FJ, Lapetra J, Pinto X, Tur JA, Garcia-Rios A, Cano-Ibanez N, Matia-Martin P, Daimiel L, Sanchez-Rodriguez R, Vidal J, Vazquez C, Ros E, Hernandez-Alonso P, Barragan R, Munoz-Martinez J, Lopez M, Gonzalez-Palacios S, Vaquero-Luna J, Crespo-Oliva E, Zulet MA, Diaz-Gonzalez V, Casas R, Fernandez-Garcia JC, Santos-Lozano JM, Galera A, Ripoll-Vera T, Buil-Cosiales P, Canudas S, Martinez-Lacruz R, Perez-Vega KA, Rios A, Lloret-Macian R, Moreno-Rodriguez A, Ruiz-Canela M, Babio N, Fajardo MDZ, Gaforio JJ. Relationship between olive oil consumption and ankle-brachial pressure index in a population at high cardiovascular risk. ATHEROSCLEROSIS. 2020. 314 ():48-57 DOI: 10.1016/j.atherosclerosis.2020.10.008 
IF: 3,919 Q: 1

Criado-Garcia J, Blanco-Molina A. Risk of thrombosis in patients with beta-thalassemia. REVISTA CLINICA ESPANOLA. 2020. 220 (3):186-187 DOI: 10.1016/j.rce.2019.06.004 
IF: 1,304 Q: 3

Fogacci F, Rizzo M, Krogager C, Kennedy C, Georges CMG, Knezevic T, Liberopoulos E, Vallee A, Perez-Martinez P, Wenstedt EFE, Satrauskiene A, Vrablik M, Cicero AFG. Safety Evaluation of alpha-Lipoic Acid Supplementation: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Clinical Studies. ANTIOXIDANTS. 2020. 9 (10):- DOI: 10.3390/antiox9101011 
IF: 5,014 Q: 1

Arandia NI, Espinosa G, Vilella CT, del Castillo AG, Rivas MR, Freire M, Hitos JAV, Parra JAT, Carballeira MR, Ballve AM, Arguelles DC, de Heredia CGDP, Ortego-Centeno N, Martinez LT, Salas XP, Chamorro AJ, Fraile IP, Munoz MR, Gimenez RAFD, Vuelta ABM, del Campo IPM, de Heredia IJP, Garcia AG, Pla VF, Aznar CPS. . Serodiscordant patients with systemic sclerosis: when antibody does not correspond to skin involvement. CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2020. 38 (3):S106-S114
IF: 3,319 Q: 1

Perez-Martinez P, Sanchez FJC, Gomez JC, Gomez-Huelgas R. Solving one of the pieces of the puzzle: COVID-19 and type 2 diabetes. REVISTA CLINICA ESPANOLA. 2020. 220 (8):507-510 DOI: 10.1016/j.rce.2020.05.003 
IF: 1,304 Q: 3

Rubio-Rivas M, Corbella X, Guillen-del-Castillo A, Vilella CT, Arguelles DC, Argibay A, Hitos JAV, Parra JAT, Gonzalez-Echavarri C, Ortego-Centeno N, Martinez LT, Carballeira MR, Ballve AM, Salas XP, Fraile IP, Chamorro AJ, Vuelta ABM, Freire M, Munoz MR,  Garcia, AG (Gonzalez Garcia, Andres)[ 20 ] ; del Campo, IPM (Martin del Campo, Isaac Pons)[ 21 ] ; Garcia, MES (Sanchez Garcia, Maria Esther)[ 22 ] ; Bello, DB (Bernal Bello, David)[ 23 ] ; Espinosa, G (Espinosa, Gerard)[ 24 ] ; Hernandez, FJG (Garcia Hernandez, Francisco Jose)[ 25 ] ; Comet, LS (Saez Comet, Luis)[ 26 ] ; Blanco, JJR (Rios Blanco, Juan Jose)[ 27 ] ; Gimenez, RAFD (de la Puebla Gimenez, Rafael Angel Fernandez)[ 28 ] ; Trigo, SS (Sanchez Trigo, Sabela)[ 29 ] ; Pla, VF (Fonollosa Pla, Vicent)[ 3 ] ; Aznar, CPS (Simeon Aznar, Carmen Pilar)[ 3 ]. Spanish scleroderma risk score (RESCLESCORE) to predict 15-year all-cause mortality in scleroderma patients at the time of diagnosis based on the RESCLE cohort: Derivation and internal validation. AUTOIMMUNITY REVIEWS. 2020. 19 (5):- DOI: 10.1016/j.autrev.2020.102507 
IF: 7,767 Q: 1

Marcos-Delgado A, Fernandez-Villa T, Martinez-Gonzalez MA, Salas-Salvado J, Corella D, Castaner O, Martinez JA, Alonso-Gomez AM, Warnberg J, Vioque J, Romaguera D, Lopez-Miranda J, Estruch R, Tinahones FJ, Lapetra J, Serra-Majem JLL, Garcia-Molina L, Tur . The Effect of Physical Activity and High Body Mass Index on Health-Related Quality of Life in Individuals with Metabolic Syndrome. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH. 2020. 17 (10):- DOI: 10.3390/ijerph17103728 
IF: 2,849 Q: 1

Perez-Martinez P, Katsiki N, Mikhailidis DP. The Role of n-3 Fatty Acids in Cardiovascular Disease: Back to the Future. ANGIOLOGY. 2020. 71 (1):10-16 DOI: 10.1177/0003319719842005 
IF: 2,255 Q: 3

Publications in 2019

Diaz-Tocados JM, Rodriguez-Ortiz ME, Almaden Y, Pineda C, Martinez-Moreno JM, Herencia C, Vergara N, de Mier MVPR, Santamaria R, Rodelo-Haad C, Casado-Diaz A, Lorenzo V, Carvalho C, Frazao JM, Felsenfeld AJ, Richards WG, Aguilera-Tejero E, Rodriguez M, Lopez I and Munoz-Castaneda JR; Calcimimetics maintain bone turnover in uremic rats despite the concomitant decrease in parathyroid hormone concentration. KIDNEY INTERNATIONAL. 95. 5.  (1064-1078). DOI: 10.1016/j.kint.2018.12.015.
IF: 8,306 Q: 1   D: 1

Camargo A, Jimenez-Lucena R, Alcala-Diaz JF, Rangel-Zuniga OA, Garcia-Carpintero S, Lopez-Moreno J, Blanco-Rojo R, Delgado-Lista J, Perez-Martinez P, van Ommen B, Malagon MM, Ordovas JM, Perez-Jimenez F, Lopez-Miranda J. Postprandial endotoxemia may influence the development of type 2 diabetes mellitus: From the CORDIOPREV study. CLINICAL NUTRITION. 2019. 38. 2. 529-538. DOI:10.1016/j.clnu.2018.03.016.
IF: 6,402 Q: 1   D: 1

Corina A, Rangel-Zuniga OA, Jimenez-Lucena R, Alcala-Diaz JF, Quintana-Navarro G, Yubero-Serrano EM, Lopez-Moreno J, Delgado-Lista J, Tinahones F, Ordovas JM, Lopez-Miranda J, Perez-Martinez P. Low Intake of Vitamin E Accelerates Cellular Aging in Patients With Established Cardiovascular Disease: The CORDIOPREV Study. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2019. 74. 6. 770-777. DOI:10.1093/gerona/gly195.
IF: 4,711 Q: 1   D: 1

Santos-Marcos JA, Haro C, Vega-Rojas A, Alcala-Diaz JF, Molina-Abril H, Leon-Acuna A, Lopez-Moreno J, Landa BB, Tena-Sempere M, Perez-Martinez P, Lopez-Miranda J, Perez-Jimenez F, Camargo A. Sex Differences in the Gut Microbiota as Potential Determinants of Gender Predisposition to Disease. MOLECULAR NUTRITION & FOOD RESEARCH. 2019. 63. 7. DOI:10.1002/mnfr.201800870.
IF: 4,653 Q: 1   D: 1

Gomez-Delgado F, Alcala-Diaz JF, Leon-Acuna A, Lopez-Moreno J, Delgado-Lista J, Gomez-Marin B, Roncero-Ramos I, Yubero-Serrano EM, Rangel-Zuniga OA, Vals-Delgado C, Luque RM, Ordovas JM, Lopez-Miranda J, Perez-Martinez P. Apolipoprotein E genetic variants interact with Mediterranean diet to modulate postprandial hypertriglyceridemia in coronary heart disease patients: CORDIOPREV study. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 2019. 49. 8. DOI:10.1111/eci.13146.
IF: 2,784 Q: 1

Solomon SD, McMurray JJV, Anand IS, Ge J, Lam CSP, Maggioni AP, Martinez F, Packer M, Pfeffer MA, Pieske B, Redfield MM, Rouleau JL, van Veldhuisen DJ, Zannad F, Zile MR, Desai AS, Claggett B, Jhund PS, Boytsov SA, Comin-Colet J, Cleland J, Dungen HD, Gon; Angiotensin-Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction. NEW ENGLAND JOURNAL OF MEDICINE. 384. 17. (1609-1620). DOI: 10.1056/NEJMoa1908655.
IF: 70,67 Q: 1   D: 1

Sayon-Orea C, Razquin C, Bullo M, Corella D, Fito M, Romaguera D, Vioque J, Alonso-Gomez AM, Warnberg J, Martinez JA, Serra-Majem L, Estruch R, Tinahones FJ, Lapetra J, Pinto X, Tur JA, Lopez-Miranda J, Bueno-Cavanillas A, Delgado-Rodriguez M, Matia-Martin P, Daimiel L, Sanchez VM, Vidal J, Vazquez C, Ros E, Ruiz-Canela M, Sorli JV, Castaner O, Fiol M, Navarrete-Munoz EM, Aros F, Gomez-Gracia E, Zulet MA, Sanchez-Villegas A, Casas R, Bernal-Lopez R, Santos-Lozano JM, Corbella E, Bouzas C, Garcia-Arellano A, Basora J, Asensio EM, Schroder H, Monino M, de la Hera MG, Tojal-Sierra L, Toledo E, Diaz-Lopez A, Goday A, Salas-Salvado J, Martinez-Gonzalez MA; Effect of a Nutritional and Behavioral Intervention on Energy-Reduced Mediterranean Diet Adherence Among Patients With Metabolic Syndrome: Interim Analysis of the PREDIMED-Plus Randomized Clinical Trial. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. 322. 15. (1486-1499). DOI: 10.1001/jama.2019.14630.
IF: 51,273 Q: 1   D: 1

Roe MT, Li QH, Bhatt DL, Bittner VA, Diaz R, Goodman SG, Harrington RA, Jukema JW, Lopez-Jaramillo P, Lopes RD, Louie MJ, Moriarty PM, Szarek M, Vogel R, White HD, Zeiher AM, Baccara-Dinet MT, Steg PG, Schwartz GG. (ODYSSEY OUTCOMES Investigators). Risk Categorization Using New American College of Cardiology/American Heart Association Guidelines for Cholesterol Management and Its Relation to Alirocumab Treatment Following Acute Coronary Syndromes. CIRCULATION. 140. 19. (1578-1589). DOI: 10.1161/CIRCULATIONAHA.119.042551.
IF: 23,054 Q1  D1

Ellis KL, de Isla LP, Alonso R, Fuentes F, Watts GF, Mata P; Value of Measuring Lipoprotein(a) During Cascade Testing for Familial Hypercholesterolemia. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 73. 9. (1029-1039). DOI: 10.1016/j.jacc.2018.12.037.
IF: 18,639 Q: 1   D: 1

Salas-Salvado J, Diaz-Lopez A, Ruiz-Canela M, Basora J, Fito M, Corella D, Serra-Majem L, Warnberg J, Romaguera D, Estruch R, Vidal J, Martinez JA, Aros F, Vazquez C, Ros E, Vioque J, Lopez-Miranda J, Bueno-Cavanillas A, Tur JA, Tinahones FJ, Martin V, La; Effect of a Lifestyle Intervention Program With Energy-Restricted Mediterranean Diet and Exercise on Weight Loss and Cardiovascular Risk Factors: One-Year Results of the PREDIMED-Plus Trial. DIABETES CARE. 42. 5. (777-788). DOI: 10.2337/dc18-0836.
IF: 15,27 Q: 1   D: 1

Martinez-Gonzalez MA, Buil-Cosiales P, Corella D, Bullo M, Fito M, Vioque J, Romaguera D, Martinez JA, Warnberg J, Lopez-Miranda J, Estruch R, Bueno-Cavanillas A, Aros F, Tur JA, Tinahones F, Serra-Majem L, Martin V, Lapetra J, Vazquez C, Pinto X, Vidal J; Cohort Profile: Design and methods of the PREDIMED-Plus randomized trial. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 48. 2. (387-+). DOI: 10.1093/ije/dyy225.
IF: 7,339 Q: 1   D: 1

Gutierrez-Mariscal FM, Yubero-Serrano EM, Villalba JM, Lopez-Miranda J. Coenzyme Q(10): From bench to clinic in aging diseases, a translational review. CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION. 2019. 59. 14. 2240-2257. DOI:10.1080/10408398.2018.1442316.
IF: 6,704 Q: 1   D: 1

Papandreou C, Diaz-Lopez A, Babio N, Martinez-Gonzalez MA, Bullo M, Corella D, Fito M, Romaguera D, Vioque J, Alonso-Gomez AM, Warnberg J, Martinez AJ, Serra-Majem L, Estruch R, Fernandez-Garcia JC, Lapetra J, Pinto X, Tur JA, Garcia-Rios A, Bueno-Cavanil; Long Daytime Napping Is Associated with Increased Adiposity and Type 2 Diabetes in an Elderly Population with Metabolic Syndrome. JOURNAL OF CLINICAL MEDICINE. 8. 7. DOI: 10.3390/jcm8071053.
IF: 5,688 Q: 1   D: 1

Gulseth HL, Gjelstad IMF, Tiereny AC, McCarthy D, Lovegrove JA, Defoort C, Blaak EE, Lopez-Miranda J, Dembinska-Kiec A, Riserus U, Roche HM, Drevon CA, Birkeland KI; Effects of dietary fat on insulin secretion in subjects with the metabolic syndrome. EUROPEAN JOURNAL OF ENDOCRINOLOGY. 180. 5. (321-328). DOI: 10.1530/EJE-19-0022.
IF: 5,107 Q: 1

De Larriva APA, Alonso A, Norby FL, Roetker NS, Folsom AR; Circulating ceruloplasmin, ceruloplasmin-associated genes and the incidence of venous thromboembolism in the Atherosclerosis Risk in Communities study. JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 17. 5. (818-826). DOI: 10.1111/jth.14420.
IF: 4,662 Q: 1

Tresserra-Rimbau A, Castro-Barquero S, Vitelli-Storelli F, Becerra-Tomas N, Vazquez-Ruiz Z, Diaz-Lopez A, Corella D, Castaner O, Romaguera D, Vioque J, Alonso-Gomez AM, Warnberg J, Martinez JA, Serra-Majem L, Estruch R, Tinahones FJ, Lapetra J, Pinto X, Tur JA, Lopez-Miranda J, Garcia-Molina L, Delgado-Rodriguez M, Matia-Martin P, Daimiel L, Rubin-Garcia M, Vidal J, Galdon A, Ros E, Basterra-Gortari FJ, Babio N, Sorli JV, Hernaez A, Konieczna J, Notario-Barandiaran L, Tojal-Sierra L, Perez-Lopez J, Abete I, Alvarez-Perez J, Fernandez-Garcia JC, Santos-Lozano JM, Galera-Cusi A, Julibert A, Ruiz-Canela M, Martinez-Lacruz R, Perez-Vega KA, Galmes-Panades AM, Pastor-Polo C, Moreno-Rodriguez A, Gea A, Fito M, Lamuela-Raventos RM, Salas-Salvado J; Associations between Dietary Polyphenols and Type 2 Diabetes in a Cross-Sectional Analysis of the PREDIMED-Plus Trial: Role of Body Mass Index and Sex. ANTIOXIDANTS. 8. 11. DOI: 10.3390/antiox8110537.
IF: 4,52 Q: 1   D: 1

del Rio-Moreno M, Alors-Perez E, Gonzalez-Rubio S, Ferrin G, Reyes O, Rodriguez-Peralvarez M, Sanchez-Frias ME, Sanchez-Sanchez R, Ventura S, Lopez-Miranda J, Kineman RD, de la Mata M, Castano JP, Gahete MD, Luque RM; Dysregulation of the Splicing Machinery Is Associated to the Development of Nonalcoholic Fatty Liver Disease. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 104. 8. (3389-3402). DOI: 10.1210/jc.2019-00021.
IF: 5,605 Q: 1

Alvarez-Alvarez I, Martinez-Gonzalez MA, Sanchez-Tainta A, Corella D, Diaz-Lopez A, Fito M, Vioque J, Romaguera D, Martinez JA, Warnberg J, Lopez-Miranda J, Estruch R, Bueno-Cavanillas A, Aros F, Tur JA, Tinahones FJ, Serra-Majem L, Martin V, Lapetra J, F; Adherence to an Energy-restricted Mediterranean Diet Score and Prevalence of Cardiovascular Risk Factors in the PREDIMED-Plus: A Cross-sectional Study. REVISTA ESPANOLA DE CARDIOLOGIA. 72. 11. (925-934). DOI: 10.1016/j.rec.2018.08.010.
IF: 5,078 Q: 1

Santos-Marcos JA, Perez-Jimenez F, Camargo A. The role of diet and intestinal microbiota in the development of metabolic syndrome. JOURNAL OF NUTRITIONAL BIOCHEMISTRY. 2019. 70. 1-27. DOI:10.1016/j.jnutbio.2019.03.017.
IF: 4,414 Q: 1

Perez-Calahorra S, Laclaustra M, Marco-Benedi V, Lamiquiz-Moneo I, Pedro-Botet J, Plana N, Sanchez-Hernandez RM, Amor AJ, Almagro F, Fuentes F, Suarez-Tembra M, Civeira F; Effect of lipid-lowering treatment in cardiovascular disease prevalence in familial hypercholesterolemia. ATHEROSCLEROSIS. 284. (245-252). DOI: 10.1016/j.atherosclerosis.2019.02.003.
IF: 4,255 Q: 1

Masana L, Ibarretxe D, Rodriguez-Borjabad C, Plana N, Valdivielso P, Pedro-Botet J, Civeira F, Lopez-Miranda J, Guijarro C, Mostaza J, Pinto X; Toward a new clinical classification of patients with familial hypercholesterolemia: One perspective from Spain. ATHEROSCLEROSIS. 287. (89-92). DOI: 10.1016/j.atherosclerosis.2019.06.905.
IF: 4,255 Q: 1

Miramontes-Gonzalez JP, Usategui-Martin R, de Isla LP, Alonso R, Muniz-Grijalvo O, Diaz-Diaz JL, Zambon D, Jimenez FF, Martin-Vallejo J, Gude AER, Jimenez DL, Padro T, Gonzalez-Sarmiento R, Mata P; VEGFR2 and OPG genes modify the risk of subclinical coronary atherosclerosis in patients with familial hypercholesterolemia. ATHEROSCLEROSIS. 285. (17-22). DOI: 10.1016/j.atherosclerosis.2019.03.019.
IF: 4,255 Q: 1

Leon-Acuna A, Torres-Pena JD, Alcala-Diaz JF, Vals-Delgado C, Roncero-Ramos I, Yubero-Serrano E, Tinahones FJ, Castro-Clerico M, Delgado-Lista J, Ordovas JM, Lopez-Miranda J, Perez-Martinez P; Lifestyle factors modulate postprandial hypertriglyceridemia: From the CORDIOPREV study. ATHEROSCLEROSIS. 290. (118-124). DOI: 10.1016/j.atherosclerosis.2019.09.025.
IF: 4,255 Q: 1

Davila LA, Bermudez V, Aparicio D, Cespedes V, Escobar MC, Duran-Aguero S, Cisternas S, Costa JD, Rojas-Gomez D, Reyna N, Lopez-Miranda J. Effect of Oral Nutritional Supplements with Sucromalt and Isomaltulose versus Standard Formula on Glycaemic Index, Entero-Insular Axis Peptides and Subjective Appetite in Patients with Type 2 Diabetes: A Randomised Cross-Over Study. NUTRIENTS. 2019. 11. 7. DOI: 10.3390/nu11071477.
IF: 4,171 Q: 1

Cano-Ibanez N, Gea A, Martinez-Gonzalez MA, Salas-Salvado J, Corella D, Zomeno MD, Romaguera D, Vioque J, Aros F, Warnberg J, Martinez JA, Serra-Majem L, Estruch R, Tinahones FJ, Lapetra J, Pinto X, Tur JA, Garcia-Rios A, Riquelme-Gallego B, Delgado-Rodri; Dietary Diversity and Nutritional Adequacy among an Older Spanish Population with Metabolic Syndrome in the PREDIMED-Plus Study: A Cross-Sectional Analysis. NUTRIENTS. 11. 5. DOI: 10.3390/nu11050958.
IF: 4,171 Q: 1

Bibiloni MD, Julibert A, Bouzas C, Martinez-Gonzalez MA, Corella D, Salas-Salvado J, Zomeno MD, Vioque J, Romaguera D, Martinez JA, Warnberg J, Lopez-Miranda J, Estruch R, Bueno-Cavanillas A, Aros F, Tinahones F, Serra-Majem L, Martin V, Lapetra J, Vazque; Nut Consumptions as a Marker of Higher Diet Quality in a Mediterranean Population at High Cardiovascular Risk. NUTRIENTS. 11. 4. DOI: 10.3390/nu11040754.
IF: 4,171 Q: 1

Papandreou C, Babio N, Diaz-Lopez A, Martinez-Gonzalez MA, Becerra-Tomas N, Corella D, Schroder H, Romaguera D, Vioque J, Alonso-Gomez AM, Warnberg J, Martinez AJ, Serra-Majem L, Estruch R, Munoz-Garach A, Lapetra J, Pinto X, Tur JA, Garcia-Rios A, Bueno-; Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk. NUTRIENTS. 11. 4. DOI: 10.3390/nu11040761.
IF: 4,171 Q: 1

Julibert A, Bibiloni MD, Bouzas C, Martinez-Gonzalez MA, Salas-Salvado J, Corella D, Zomeno MD, Romaguera D, Vioque J, Alonso-Gomez AM, Warnberg J, Martinez JA, Serra-Majem L, Estruch R, Tinahones FJ, Lapetra J, Pinto X, Lopez-Miranda J, Garcia-Molina L, ; Total and Subtypes of Dietary Fat Intake and Its Association with Components of the Metabolic Syndrome in a Mediterranean Population at High Cardiovascular Risk. NUTRIENTS. 11. 7. DOI: 10.3390/nu11071493.
IF: 4,171 Q: 1

Ditano-Vazquez P, Torres-Pena JD, Galeano-Valle F, Perez-Caballero AI, Demelo-Rodriguez P, Lopez-Miranda J, Katsiki N, Delgado-Lista J, Alvarez-Sala-Walther LA; The Fluid Aspect of the Mediterranean Diet in the Prevention and Management of Cardiovascular Disease and Diabetes: The Role of Polyphenol Content in Moderate Consumption of Wine and Olive Oil. NUTRIENTS. 11. 11. DOI: 10.3390/nu11112833.
IF: 4,171 Q: 1

Clemente-Postigo M, Oliva-Olivera W, Coin-Araguez L, Ramos-Molina B, Giraldez-Perez RM, Lhamyani S, Alcaide-Torres J, Perez-Martinez P, El Bekay R, Cardona F, Tinahones FJ; Metabolic endotoxemia promotes adipose dysfunction and inflammation in human obesity. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 316. 2 (E319-E332). DOI: 10.1152/ajpendo.00277.2018.
IF: 4,125 Q: 1

Rodriguez-Ortiz ME, Gomez-Delgado F, de Larriva APA, Canalejo A, Gomez-Luna P, Herencia C, Lopez-Moreno J, Rodriguez M, Lopez-Miranda J, Almaden Y. Serum Magnesium is associated with Carotid Atherosclerosis in patients with high cardiovascular risk (CORDIOPREV Study). SCIENTIFIC REPORTS. 2019. 9. DOI:10.1038/s41598-019-44322-z.
IF: 4,011 Q: 1

Llacer P, Nunez J, Bayes-Genis A, Martel AC, Hernandez YC, Manglano JD, Rocha PA, Rangel LS, Del Olmo VG, Manzano L, Perez-Barquero MM. Digoxin and prognosis of heart failure in older patients with preserved ejection fraction: Importance of heart rate. Results from an observational and multicenter study. EUROPEAN JOURNAL OF INTERNAL MEDICINE. 2019. 60. 18-23. DOI:10.1016/j.ejim.2018.10.010.
IF: 3,66 Q: 1

Formiga F, Chivite D, Corbella X, Conde-Martel A, Arevalo-Lorido JC, Trullas JC, Silvestre JP, Garcia SC, Manzano L, Montero-Perez-Barquero M (Rica Investigators Grp: Alvarez-Rocha P, Anarte L, Aramburu-Bodas O, Carrascosa S, Casado J, Cerqueiro JM, Diez-. Influence of potassium levels on one-year outcomes in elderly patients with acute heart failure. EUROPEAN JOURNAL OF INTERNAL MEDICINE. 2019. 60. 24-30. DOI:10.1016/j.ejim.2018.10.016.
IF: 3,66 Q: 1

Quiros-Lopez R, Manzano-Espinosa L, Bilbao A, Perez-Barquero M, Cepeda-Rodrigo JM, Escobar-Martinez A; External validation of the CACE-HF risk score for mortality in patients with heart failure. EUROPEAN JOURNAL OF INTERNAL MEDICINE. 66. (35-40). DOI: 10.1016/j.ejim.2019.05.010.
IF: 3,66 Q: 1

Lopez-Bascon MA, Calderon-Santiago M, Diaz-Lozano A, Camargo A, Lopez-Miranda J, Priego-Capote F; Development of a qualitative/quantitative strategy for comprehensive determination of polar lipids by LC-MS/MS in human plasma. ANALYTICAL AND BIOANALYTICAL CHEMISTRY. DOI: 10.1007/s00216-019-02261-8.
IF: 3,286 Q: 1

de Isla LP, Arroyo-Olivares R, Muniz-Grijalvo O, Diaz-Diaz JL, Zambon D, Fuentes F, Munoz-Torrero JFS, Mediavilla JD, Gonzalez-Estrada A, Miramontes-Gonzalez JP, de Andres R, Mauri M, Mosquera D, Cepeda JM, Suarez L, Barba-Romero MA, Argueso R, Alvarez-Banos P, Michan A, Romero-Jimenez MJ, Garcia-Cruces J, Padro T, Alonso R, Mata P; Long-term effect of 2 intensive statin regimens on treatment and incidence of cardiovascular events in familial hypercholesterolemia: The SAFEHEART study. JOURNAL OF CLINICAL LIPIDOLOGY. 13. 6. (989-996). DOI: 10.1016/j.jacl.2019.10.005.
IF: 3,581 Q: 2

Yubero-Serrano EM, Lopez-Moreno J, Gomez-Delgado F, Lopez-Miranda J. Extra virgin olive oil: More than a healthy fat. EUROPEAN JOURNAL OF CLINICAL NUTRITION. 2019. 72. S. 8-17. DOI:10.1038/s41430-018-0304-x.
IF: 3,114 Q: 2

Antoniazzi L, Arroyo-Olivares R, Bittencourt MS, Tada MT, Lima I, Jannes CE, Krieger JE, Pereira AC, Quintana-Navarro G, Muniz-Grijalvo O, Diaz-Diaz JL, Zambon D, Mata P, Santos RD; Association of dietary components with dyslipidemia and low-grade inflammation biomarkers in adults with heterozygous familial hypercholesterolemia from different countries. EUROPEAN JOURNAL OF CLINICAL NUTRITION. 73. 12. (1622-1625). DOI: 10.1038/s41430-019-0529-3.
IF: 3,114 Q: 2

Kolovou GD, Watts GF, Mikhailidis DP, Perez-Martinez P, Mora S, Bilianou H, Panotopoulos G, Katsiki N, Ooi TC, Lopez-Miranda J, Tybjaerg-Hansen A, Tentolouris N, Nordestgaard BG; Postprandial Hypertriglyceridaemia Revisited in the Era of Non-Fasting Lipid Profile Testing: A 2019 Expert Panel Statement, Main Text. CURRENT VASCULAR PHARMACOLOGY. 17. 5. (498-514). DOI: 10.2174/1570161117666190507110519.
IF: 2,583 Q: 2

Kolovou GD, Watts GF, Mikhailidis DP, Perez-Martinez P, Mora S, Mora S, Bilianou H, Panotopoulos G, Katsiki N, Ooi TC, Lopez-Miranda J, Tybjaerg-Hansen A, Tentolouris N, Nordestgaard BG; Postprandial Hypertriglyceridaemia Revisited in the Era of Non-Fasting Lipid Profile Testing: A 2019 Expert Panel Statement, Narrative Review. CURRENT VASCULAR PHARMACOLOGY. 17. 5. (515-537). DOI: 10.2174/1570161117666190503123911.
IF: 2,583 Q: 2

Pedro-Botet J, Lopez-Miranda J, Badimon L, Civeira F, Guijarro C, Millan J, Mostaza JM, Pinto X, Valdivielso P, Masana L; Overall Mortality and LDL Cholesterol Reduction in Secondary Prevention Trials of Cardiovascular Disease. AMERICAN JOURNAL OF CARDIOVASCULAR DRUGS. DOI: 10.1007/s40256-019-00376-y.
IF: 2,578 Q: 2

Arroyo-Olivares R, Alonso R, Quintana-Navarro G, Fuentes-Jimenez F, Mata N, Muniz-Grijalvo O, Diaz-Diaz JL, Zambon D, Arrieta F, Garcia-Cruces J, Garrido-Sanjuan JA, Banegas JR, Mata P; Adults with familial hypercholesterolaemia have healthier dietary and lifestyle habits compared with their non-affected relatives: the SAFEHEART study. PUBLIC HEALTH NUTRITION. 22. 8. (1433-1443). DOI: 10.1017/S1368980018003853.
IF: 2,526 Q: 2

Trullas JC, Casado J, Morales-Rull JL, Formiga F, Conde-Martel A, Quiros R, Epelde F, Gonzalez-Franco A, Manzano L, Montero-Perez-Barquero M. Prevalence and outcome of diuretic resistance in heart failure. INTERNAL AND EMERGENCY MEDICINE. 2019. 14. 4. 529-537. DOI: 10.1007/s11739-018-02019-7.
IF: 2,335 Q: 2

Catoi AF, Vodnar DC, Corina A, Nikolic D, Citarrella R, Perez-Martinez P, Rizzo M; Gut Microbiota, Obesity and Bariatric Surgery: Current Knowledge and Future Perspectives. CURRENT PHARMACEUTICAL DESIGN. 25. 18. (2038-2050). DOI: 10.2174/1381612825666190708190437.
IF: 2,412 Q: 3

Corina A, Abrudan MB, Nikolic D, Catoi AF, Chianetta R, Castellino G, Citarrella R, Stoian AP, Perez-Martinez P, Rizzo, M; Effects of Aging and Diet on Cardioprotection and Cardiometabolic Risk Markers. CURRENT PHARMACEUTICAL DESIGN. 25. 35. (3704-3714). DOI: 10.2174/1381612825666191105111232.
IF: 2,412 Q: 3

Huerta-Preciado J, Franco J, Formiga F, Iborra PL, Epelde F, Franco AG, Ormaechea G, Manzano L, Cepeda-Rodrigo JM, Montero-Perez-Barquero M. With the Aid of RICA Investigators Group: Rocha, PA; Anarte, L; Arevalo-Lorido, JC; Cabanes, Y; Carrascosa, S; Izq. Differential characteristics of acute heart failure in very elderly patients: the prospective RICA study. AGING CLINICAL AND EXPERIMENTAL RESEARCH. 2019. DOI: 10.1007/s40520-019-01363-8.
IF: 2,331 Q: 3

Garcia-Hernandez FJ, Castillo-Palma MJ, Tolosa-Vilella C, Guillen-del Castillo A, Rubio-Rivas M, Freire M, Vargas-Hitos JA, Todoli-Parra JA, Rodriguez-Carballeira M, Espinosa-Garriga G, Colunga-Arguelles D, Ortego-Centeno N, Trapiella-Martinez L, Rodero-R; Pulmonary hypertension in Spanish patients with systemic sclerosis. Data from the RESCLE registry. CLINICAL RHEUMATOLOGY. 38. 4.  (1117-1124). DOI: 10.1007/s10067-018-4390-x.
IF: 2,293 Q: 3

Kolovou GD, Watts GF, Mikhailidis DP, Perez-Martinez P, Mora S, Bilianou H, Panotopoulos G, Katsiki N, Ooi TC, Lopez-Miranda J, Tybjaerg-Hansen A, Tentolouris N, Nordestgaard BG; Postprandial Hypertriglyceridaemia Revisited in the Era of Non-fasting Lipid Profiles: Executive Summary of a 2019 Expert Panel Statement. CURRENT VASCULAR PHARMACOLOGY. 17. 5. (538-540). DOI: 10.2174/1570161117999190517115432.
IF: 2,087 Q: 3

Franco J, Formiga F, Corbella X, Conde-Martel A, Llacer P, Rocha PA, Gorricho GO, Satue J, Rangel LS, Manzano L, Montero-Perez-Barquero M. (Grp Invest RICA: Anarte L, Aramburu O, Arevalo-Lorido JC, Carrascosa S, Carrera M, Cepeda JM, Cerqueiro JM, Davila . De novo acute heart failure: Clinical features and one-year mortality in the Spanish nationwide Registry of Acute Heart Failure. MEDICINA CLINICA. 2019. 152. 4. 127-134. DOI:10.1016/j.medcli.2018.05.012.
IF: 1,277 Q: 3

Montero-Perez-Barquero M, Manzano L. Quality of life, compliance and satisfaction of patients with atrial fibrillation who are undergoing anticoagulant treatment. REVISTA CLINICA ESPANOLA. 2019. 219. 6. 320-321. DOI:10.1016/j.rce.2019.03.002.
IF: 1,184 Q: 3

Amoros JG, Formiga F, Bodas OA, Arxe AA, Martel AC, Simon MAQ, Juanes RO, Bartolome JAS, Ramos MFD, Perez-Barquero MM. Hemoconcentration as a prognostic factor after hospital discharge in acute heart failure in the RICA registry. REVISTA CLINICA ESPANOLA. 2019. 219. 1. 1-9. DOI:10.1016/j.rce.2018.07.003.
IF: 1,043 Q: 3

Chivite D, Franco J, Formiga F, Salamanca-Bautista P, Manzano L, Conde-Martel A, Arevalo-Lorido JC, Suarez-Pedreira I, Casado-Cerrada J, Montero-Perez-Barquero M. The short-term prognostic value of C-reactive protein in elderly patients with acute heart failure. REVISTA CLINICA ESPANOLA. 2019. 219. 1. 10-17. DOI:10.1016/j.rce.2018.04.019.
IF: 1,043 Q: 3

Ruiz-Ruiz F, Medrano FJ, Santos-Lozano JM, Rodriguez-Torres P, Navarro-Puerto A, Calderon EJ, del Rio CAO, Marin-Leon I, Romero-Alonso A, Varela-Aguilar JM, Martinez MNB, Molina MAB, Vales EC, Montoro AE, Dalmau FGB, Hernandez AL, Rodriguez JAN, Santos JT; Anticoagulant treatment of medical patients with complex clinical conditions. REVISTA CLINICA ESPANOLA. 219. 1. (34-43). DOI: 10.1016/j.rce.2018.04.007.
IF: 1,043 Q: 3

Bernabeu-Wittel M, Diez-Manglano J, Nieto-Martin D, Ramirez-Duque N, Ollero-Baturone M.  en representación de los investigadores del Proyecto PROFUND; Investigadores del Proyecto PROFUND: Abella-Vazquez, L; Aguayo-Canela, M; Albert-Coll, M; Aleman, A; Ali; Simplification of the Barthel scale for screening for frailty and severe dependency in polypathological patients. REVISTA CLINICA ESPANOLA. 2019. 8. (433-439). DOI: 10.1016/j.rce.2019.04.005.
IF: 1,043 Q: 3

Arevalo-Lorido JC, Carretero-Gomez J, Robles NR, Llacer P, Carrera M, Suarez-Pedreira I, Alvarez-Rocha P, Manzano-Espinosa L, Cepeda-Rodrigo JM, Montero-Perez-Barquero M. (on behalf of the RICA Investigators Group. Rocha, PA; Anarte, L; Arevalo-Lorido, JC. Prognostic Role of Hyponatremia in Heart Failure Patients Depending on Renal Disease: Clinical Evidence. CARDIOLOGY. 2019. 144. 1-2. 1-8. DOI: 10.1159/000502566  
IF: 1,561 Q: 4

Garcia-Rios A, Garcia AC, Perez-Jimenez F, Perez-Martinez P. Gut microbiota: Anew protagonist in the risk of cardiovascular disease?. CLINICA E INVESTIGACION EN ARTERIOSCLEROSIS. 2019. 31. 4. 178-185. DOI:10.1016/j.arteri.2018.11.003.

Perez-Martinez P, Huelgas RG, Perez-Jimenez F. Healthy planetary diet: do we have to rethink the recommendations based on the Mediterranean diet?. CLINICA E INVESTIGACION EN ARTERIOSCLEROSIS. 2019. 31. 5. 218-221. DOI:10.1016/j.arteri.2019.09.001.

Sanchez-Chaparro MA, Perez-Martinez P, Ibarretxe D, Suarez-Tembra M, Valdivielso P, Ros E, Martinez S, Cenarro A, Sanchez MA, Ibarretxe D, Suarez M, Muniz O, Perez P, Blanco A, Vea A, Toro R, Serra E, Romero MJ, Rodriguez C, Pardo A, Marquez L, de los San; Criteria for referring patients to Spanish Atherosclerosis Society lipid units. CLINICA E INVESTIGACION EN ARTERIOSCLEROSIS. 31. 1. (26-30). DOI: 10.1016/j.arteri.2018.04.005.
 
Ascaso JF, Civeira F, Guijarro C, Miranda JL, Masana L, Mostaza JM, Pedro-Botet J, Pinto X, Valdivielso P; Indications of PCSK9 inhibitors in clinical practice. Recommendations of the Spanish Sociey of Arteriosclerosis (SEA), 2019. CLINICA E INVESTIGACION EN ARTERIOSCLEROSIS. 31. 3.  (128-139). DOI: 10.1016/j.arteri.2019.04.002.

Pascual V, Martinez PP, Fernandez JM, Sola R, Pallares V, Secin AR, Jimenez FP, Ros E; SEA/SEMERGEN consensus document 2019: Dietary recommendations in the prevention of cardiovascular disease. CLINICA E INVESTIGACION EN ARTERIOSCLEROSIS. 31. 4. (186-201). DOI: 10.1016/j.arteri.2019.02.004.

Publications in 2018

Gomez-Marin B, Gomez-Delgado F, Lopez-Moreno J, Alcala-Diaz JF, Jimenez-Lucena R, Torres-Pena JD, Garcia-Rios A, Ortiz-Morales AM, Yubero-Serrano EM, Malagon MD, Lai CQ, Delgado-Lista J, Ordovas JM, Lopez-Miranda J, Perez-Martinez P. Long-term consumption of a Mediterranean diet improves postprandial lipemia in patients with type 2 diabetes: the Cordioprev randomized trial. AMERICAN JOURNAL OF CLINICAL NUTRITION. 2018; 108(5):963-970.
IF: 6,549 Q: 1   D: 1

Garcia-Rios A, Alcala-Diaz JF, Gomez-Delgado F, Delgado-Lista J, Marin C, Leon-Acuna A, Camargo A, Rodriguez-Cantalejo F, Blanco-Rojo R, Quintana-Navarro G, Ordovas JM, Perez-Jimenez F, Lopez-Miranda J, Perez-Martinez P. Beneficial effect of CETP gene polymorphism in combination with a Mediterranean diet influencing lipid metabolism in metabolic syndrome patients: CORDIOPREV study. CLINICAL NUTRITION. 2018; 37(1):229-234.
IF: 5,496 Q: 1   D: 1

Roncero-Ramos I, Rangel-Zuniga OA, Lopez-Moreno J, Alcala-Diaz JF, Perez-Martinez P, Jimenez-Lucena R, Castano JP, Roche HM, Delgado-Lista J, Ordovas JM, Camargo A, Lopez-Miranda J. Mediterranean Diet, Glucose Homeostasis, and Inflammasome Genetic Variants: The CORDIOPREV Study. MOLECULAR NUTRITION & FOOD RESEARCH. 2018; 62(9):Núm artículo 1700960
IF: 5,151 Q: 1   D: 1

Gomez-Delgado F, Delgado-Lista J, Lopez-Moreno J, Rangel-Zuniga OA, Alcala-Diaz JF, Leon-Acuna A, Corina A, Yubero-Serrano E, Torres-Pena JD, Camargo A, Garcia-Rios A, Caballero J, Castano J, Ordovas JM, Lopez-Miranda J, Perez-Martinez P. Telomerase RNA Component Genetic Variants Interact With the Mediterranean Diet Modifying the Inflammatory Status and its Relationship With Aging: CORDIOPREV Study. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2018; 73(3):327-332.
IF: 4,902 Q: 1   D: 1

Lopez-Moreno J, Quintana-Navarro GM, Delgado-Lista J, Garcia-Rios A, Alcala-Diaz JF, Gomez-Delgado F, Camargo A, Perez-Martinez P, Tinahones FJ, Striker GE, Perez-Jimenez F, Villalba JM, Lopez-Miranda J, Yubero-Serrano EM. Mediterranean Diet Supplemented With Coenzyme Q(10) Modulates the Postprandial Metabolism of Advanced Glycation End Products in Elderly Men and Women. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2018; 73(3):340-346.
IF: 4,902 Q: 1   D: 1

Jimenez-Lucena R, Rangel-Zuniga OA, Alcala-Diaz JF, Lopez-Moreno J, Roncero-Ramos I, Molina-Abril H, Yubero-Serrano EM, Caballero-Villarraso J, Delgado-Lista J, Castano JP, Ordovas JM, Perez-Martinez P, Camargo A, Lopez-Miranda J. Circulating miRNAs as Predictive Biomarkers of Type 2 Diabetes Mellitus Development in Coronary Herat Disease Patients from the CORDIOPREV Study. MOLECULAR THERAPY-NUCLEIC ACIDS. 2018; 12:146-157.
IF: 5,66 Q: 1   D: 1

Jimenez-Lucena R, Camargo A, Alcala-Diaz JF, Romero-Baldonado C, Luque RM, van Ommen B, Delgado-Lista J, Ordovas JM, Perez-Martinez P, Rangel-Zuniga OA, Lopez-Miranda J. A plasma circulating miRNAs profile predicts type 2 diabetes mellitus and prediabetes: from the CORDIOPREV study. EXPERIMENTAL AND MOLECULAR MEDICINE. 2018; 50:Núm artículo 168
IF: 5,584 Q: 1

Roncero-Ramos I, Jimenez-Lucena R, Alcala-Diaz JF, Vals-Delgado C, Arenas-Larriva AP, Rangel-Zuniga OA, Leon-Acuna A, Malagon MM, Delgado-Lista J, Perez-Martinez P, Ordovas JM, Camargo A, Lopez-Miranda J. Alpha cell function interacts with diet to modulate prediabetes and Type 2 diabetes. JOURNAL OF NUTRITIONAL BIOCHEMISTRY. 2018; 62:247-256.
IF: 4,414 Q: 1

Torres-Pena JD, Garcia-Rios A, Delgado-Casado N, Gomez-Luna P, Alcala-Diaz JF, Yubero-Serrano EM, Gomez-Delgado F, Leon-Acuna A, Lopez-Moreno J, Camargo A, Tinahones FJ, Delgado-Lista J, Ordovas JM, Perez-Martinez P, Lopez-Miranda J. Mediterranean diet improves endothelial function in patients with diabetes and prediabetes: A report from the CORDIOPREV study. ATHEROSCLEROSIS. 2018; 269:50-56.
IF: 4,467 Q: 1

Santos-Marcos, JA; Rangel-Zuniga, OA; Jimenez-Lucena, R; Quintana-Navarro, GM; Garcia-Carpintero, S; Malagon, MM; Landa, BB; Tena-Sempere, M; Perez-Martinez, P; Lopez-Miranda, J; Perez-Jimenez, F; Camargo, A. Influence of gender and menopausal status on gut microbiota. MATURITAS. 2018; 116:43-53.
IF: 3,315 Q: 1

Chivite D, Formiga F, Corbella X, Conde-Martel A, Aramburu O, Carrera M, Davila MF, Perez-Silvestre J, Manzano L, Montero-Perez-Barquero M. Basal functional status predicts one-year mortality after a heart failure hospitalization in elderly patients - The RICA prospective study. INTERNATIONAL JOURNAL OF CARDIOLOGY. 2018; 254:182-188.
IF: 4,034 Q: 2

Guisado-Espartero ME, Salamanca-Bautista P, Aramburu-Bodas O, Conde-Martel A, Arias-Jimenez JL, Llacer-Iborra P, Davila-Ramos MF, Cabanes-Hernandez Y, Manzano L, Montero-Perez-Barquero M. Heart failure with mid-range ejection fraction in patients admitted to internal medicine departments: Findings from the RICA Registry. INTERNATIONAL JOURNAL OF CARDIOLOGY. 2018; 255:124-128.
IF: 4,034 Q: 2

Lopez-Moreno J, Garcia-Carpintero S, Gomez-Delgado F, Jimenez-Lucena R, Vals-Delgado C, Alcala-Diaz JF, Roncero-Ramos I, Rangel-Zuniga OA, Yubero-Serrano EM, Malagon MM, Ordovas JM, Perez-Martinez P, Lopez-Miranda J, Camargo A. Endotoxemia is modulated by quantity and quality of dietary fat in older adults. EXPERIMENTAL GERONTOLOGY. 2018; 109:119-125.
IF: 3,224 Q: 2

Garcia-Rios A, Ordovas JM, Lopez-Miranda J, Perez-Martinez P. New diet trials and cardiovascular risk. CURRENT OPINION IN CARDIOLOGY. 2018; 33(4):423-428.
IF: 2,006 Q: 3

Franco J, Formiga F, Cepeda J, Llacer P, Arevalo-Lorido J, Cerqueiro J, Gonzalez-Franco A, Epelde F, Manzano L, Perez-Barquero MM. Influence of atrial fibrillation on the mortality of patients with heart failure with preserved ejection fraction. MEDICINA CLINICA. 2018; 150(10):376-382.
IF: 1,168 Q: 3

Sanchez-Garcia ME, Ramirez-Lara I, Gomez-Delgado F, Yubero-Serrano EM, Leon-Acuna A, Marin C, Alcala-Diaz JF, Camargo A, Lopez-Moreno J, Perez-Martinez P, Tinahones FJ, Ordovas JM, Caballero J, Blanco-Molina A, Lopez-Miranda J, Delgado-Lista J. Quantitative evaluation of capillaroscopic microvascular changes in patients with established coronary heart disease. MEDICINA CLINICA. 2018; 150(4):131-137.
IF: 1,168 Q: 3

Perez-Jimenez F, Pascual V, Meco JF, Martinez PP, Lista JD, Domenech M, Estruch R, Leon-Acuna A, Lopez-Miranda J, Sanchez-Ramos A, Ferrer CSI, Soler-Rivas C, Alberich RMS, Valdivielso P, Ros E. Document of recommendations of the SEA 2018. Lifestyle in cardiovascular prevention. CLINICA E INVESTIGACION EN ARTERIOSCLEROSIS. 2018; 30(6):280-310.

Martin SS, Giugliano RP, Murphy SA, Wasserman SM, Stein EA, Ceska R, Lopez-Miranda J, Georgiev B, Lorenzatti AJ, Tikkanen MJ, Sever PS, Keech AC, Pedersen TR, Sabatine MS. Comparison of Low-Density Lipoprotein Cholesterol Assessment by Martin/Hopkins Estimation, Friedewald Estimation, and Preparative Ultracentrifugation Insights From the FOURIER Trial. JAMA CARDIOLOGY. 2018; 3(8):749-753.
IF: 10,133 Q: 1   D: 1

Gahete MD, del Rio-Moreno M, Camargo A, Alcala-Diaz JF, Alois-Perez E, Delgado-Lista J, Reyes O, Ventura S, Perez-Martinez P, Castno JP, Lopez-Miranda J, Luque RM. Changes in Splicing Machinery Components Influence, Precede, and Early Predict the Development of Type 2 Diabetes: From the CORDIOPREV Study. EBIOMEDICINE. 2018; 37:356-365.
IF: 6,183 Q: 1   D: 1

Schroder H, Cardenas-Fuentes G, Martinez-Gonzalez MA, Corella D, Vioque J, Romaguera D, Martinez JA, Tinahones FJ, Miranda JL, Estruch R, Bueno-Cavanillas A, Aros F, Marcos A, Tur JA, Warnberg J, Serra-Majem L, Martin V, Vazquez C, Lapetra J, Pinto X, Vidal J, Daimiel L, Gaforio JJ, Matia-Martin P, Ros E, Castaner O, Lassale C, Ruiz-Canela M, Asensio EM, Basora J, Torres-Collado L, Garcia-Rios A, Abete I, Toledo E, Buil-Cosiales P, Bullo M, Goday A, Fito M, Salas-Salvado J. Effectiveness of the physical activity intervention program in the PREDIMED-Plus study: a randomized controlled trial. INTERNATIONAL JOURNAL OF BEHAVIORAL NUTRITION AND PHYSICAL ACTIVITY. 2018; 15:Núm artículo 110
IF: 5,548 Q: 1   D: 1

Grandone E, Di Micco PP, Villani M, Colaizzo D, Fernandez-Capitan C, Del Toro J, Rosa V, Bura-Riviere A, Quere I, Blanco-Molina A, Margaglione M, Monreal M. Venous Thromboembolism in Women Undergoing Assisted Reproductive Technologies: Data from the RIETE Registry. THROMBOSIS AND HAEMOSTASIS. 2018; 118(11):1962-1968.
IF: 4,952 Q: 1   D: 1

Clinical Research

Active in 2019

A multicenter, open study to assess the safety, tolerability and long-term efficacy of AMG 145 in C-LDL cholesterol in subjects with severe heterozygous familial hypercholestorolemia.
PI: Dr. Francisco Fuentes Jiménez

A randomized, double-blind, parallel-group, active-control trial to assess the efficacy and safety of LCZ696 versus Valsartan on morbidity and mortality in patients with heart failure NYHA Class II-IV).
PI: Dr.  Manuel Montero Pérez-Barquero

Open-label, Single-Arm, Multicenter Study to Evaluate the Safety, Tolerability and Efficacy of Evolocumab for LDL-C Reduction, as Add-on to Diet and Lipid-lowering Therapy, in Pediatric Subjects From 10 to 17 Years of Age With Heterozygous Familial Hypercholesterolemia (HeFH) or Homozygous Familial Hypercholesterolemia (HoFH).
PI: Dr. Francisco Fuentes Jiménez

Estudio aleatorizado, doble ciego, controlado con placebo, de grupos paralelos, multicéntrico, para demostrar los efectos de Sotagliflozina sobre los eventos cardiovasculares y renales en pacientes con diabetes tipo 2, factores de riesgo cardiovascular y función renal moderadamente reducida.
PI: Dr. Francisco Javier Delgado Lista

Estudio aleatorizado, doble ciego, controlado con placebo, de la seguridad y la eficacia de diferentes dosis y pautas posológicas de evinacumab en pacientes con hipercolesterolemia crónica a pesar del tratamiento hipolipidemiante máximo tolerado.
PI: Dr. Pablo Pérez  Martínez

Ensayo clínico de bajo nivel de intervención, abierto y multicéntrico para evaluar el efecto de alirocumab sobre el volumen, la arquitectura y la composición de la placa aterosclerótica en pacientes con Hipercolesterolemia Familiar del Registro.  SAFEHEART. Estudio ARCHITECT.
PI: Dr. Francisco Fuentes Jiménez

Estudio multicéntrico, aleatorizado, doble ciego, de grupos paralelos, con control activo y de 24 semanas de duración para evaluar el efecto de LCZ696 sobre el nivel de NTproBNP, los síntomas, la capacidad de realizar ejercicio y la seguridad en comparación con el tratamiento médico individualizado de las comorbilidades en pacientes con insuficiencia cardíaca y fracción de eyección preservada.
PI: Dr. Francisco Javier Gómez Delgado

Efecto de semaglutida una vez a la semana frente a insulin aspart tres veces al día, ambas añadidas a metformina e insulina glargina optimizada (U100), en sujetos con diabetes tipo 2  Ensayo de 52 semanas, multicéntrico, multinacional, abierto, con control activo, de dos grupos paralelos y aleatorizado en sujetos con diabetes tipo 2.
PI: Dr. Francisco Javier Delgado Lista

Pemafibrato para reducir los episodios cardiovasculares mediante la reducción de los triglicéridos en pacientes con diabetes (PROMINENT).
PI: Dr. Francisco Javier Delgado Lista 

Ensayo de extensión a largo plazo de los ensayos de fase III con hipolipemiantes, para evaluar el efecto del tratamiento a largo plazo con inclisirán administrador en inyecciones subcutáneas a sujetos con alto riesgo cardiovascular y LDL - C elevado. ORIO.
PI: Dr. Francisco Fuentes Jiménez

Efecto sobre la capacidad funcional del tratamiento con hierro intravenoso o hierro oral, comparado con placebo, en pacientes con insuficiencia cardiaca con fracción de eyección del ventrículo izquierdo preservada y anemia ferropénica. ( PREFER-HF).
PI: Dr. Manuel Montero Pérez-Barquero

Estudio multicéntrico, aleatorizado, doble ciego y controlado con placebo para evaluar el impacto de evolocumab sobre los acontecimientos cardiovasculares mayores en pacientes con riesgo cardiovascular elevado sin infarto de miocardio o ictus previo (vesa.
PI: Dr. José López Miranda

Estudio de las cardiopatias con semaglutida en pacientes con diabetes tipo 2 (SOUL).
PI: Dr. Francisco Javier Delgado Lista

 Global anticoagulant registry in the field observing treatment and putcomes in patients with treated acute venous thromboembolic events in the real world GARFIELD.
PI: Dr. Luciano López Jiménez

Estudio observacional multinacional para evaluar la seguridad de Repatha en el embarazo.
PI: Dr.  Francisco Fuentes Jiménez

EU-Wide Cross-Sectional Observational Study of Lipyd-Modifying Therapy Use in Secondary and Primary Care DA VINCI.
PI: Dr. Francisco Javier Gómez Delgado

Long-term legacy effects of LDL-C lowering with alirocumab: observational follow-up of the ODYSSEY OUTCOMES study.
PI: Dr. Francisco Fuentes Jiménez

Manejo del paciente dislipémico pre-diabético en las unidades de lípidos. Estudio PRELIPID.
PI: Dr. José López Miranda

Proyecto MERIDA. Programa de implementación del ejercicio físico en pacientes con insuficiencia cardiaca.
PI: Dr. Manuel Montero Pérez-Barquero

Estudio epidemiológico, multicéntrico y trasversal para caracterizar la prevalencia y distribución de los niveles de lipoproteína (a) en pacientes con enfermedad cardiovascular establecida.
PI: Dr. Francisco Jesús Gómez Delgado

Estudio de prevalencia de amiloidosis en insuficiencia cardiaca.
PI: Dr. Manuel Montero Pérez-Barquero

Members

Principal Investigator
José López Miranda

Co-Principal Investigators
Francisco Javier Delgado Lista
Francisco Pérez Jiménez
Pablo Pérez Martínez

Emerging Researcher
Antonio Camargo García
Antonio García Ríos
Elena María Yubero Serrano

Researchers
Juan Francisco Alcalá Díaz
Yolanda Almadén Peña
María Ángeles Blanco Molina
Rafael Ángel Fernández De La Puebla
Francisco Fuentes Jiménez
Luciano López Jiménez
Manuel Montero Pérez-Barquero
Anabel Pérez Caballero
Oriol Alberto Rangel Zuñiga

Post-Doctoral Researchers
Juan Criado García
Silvia De La Cruz Ares
Francisco Gómez Delgado
Purificación Gómez Luna
Francisco Miguel Gutiérrez Mariscal
Anabel Jiménez Morales
Ana León Acuña
Javier López Moreno
Laura Martín Piedra
Marina Mora Ortiz
Almudena Pino Ángeles
José David Torres Peña

Pre-Doctoral Researchers
Antonio Pablo Arenas De Larriva
Carolina Fernández Gandara
José Jiménez Torres
María Magdalena Pérez Cardelo
Marta Orge Millán
Alicia Podadera Herreros
Cristina Vals Delgado
Ana María Vega Rojas
Alejandro Villasanta González

Nursing, Technical, and Administrative Staff
Rosario Carreras Calero
Sofía  Castro Montero
José Andrés Morales Martínez
Blanca Morillo-Velarde Castro 
Patricia Judith Peña Orihuela
Isabel  Pérez Corral
Gracia María Quintana Navarro
Margarita Romero Monterroso
Carmen Serrano Espejo