Research groups

GC09 Nutrigenomics. Metabolic Syndrome

The Nutrigenomics. Metabolic Syndrome research group is a consolidated group of IMIBIC, bringing together both basic and clinical researchers in various scientific disciplines, such as medicine, biology, biochemistry, as well as dieticians, nursing, technical and administrative staff. Our research is mainly based on the effect of dietary components on cardiovascular risk through a double approach: the biological actions of the diet on mechanisms and factors related to the development of atherosclerosis (oxidative stress, inflammation, homeostasis or cellular signaling) and Nutrigenetics, through which we investigate how common genetic variants modulate the influence of the diet on different markers such as postprandial metabolism, endothelial function, overweight or glucose metabolism. We are also interested in the use of these strategies in others pathologies such as hypercholesterolemia, thromboembolic disease, as well as in ageing process. These approaches will allow us to modulate the pathological pathways that underlie the development of various chronic diseases (type 2 diabetes mellitus, metabolic syndrome and cardiovascular diseases).

Over the last few years, our group has been developing predictive models for assessing the risk of disease. Specifically, we are developing innovative models to evaluate biological senescence, coronary heart disease treatment choice and miRNAs plasma levels-based model for type 2 diabetes mellitus development. Moreover, due to the complex nature of gene-environment interactions, another important aim of our research is to establish an appropriate dietary therapy in according to the disease, for personalised nutrition.

Our research group is highly motivated toward internationalisation. In fact, we are currently taking part in two international consortiums. POWER2DM, whose objective is to develop individual self-control of diabetes; and FAME, for the identification of new disease biomarkers.

The Principal Investigator (PI) of the group, José López Miranda, is also PI of both CIBER Physiopathology of Obesity and Nutrition (CIBERobn) and the PAIDI CTS-525. Other collaborations include highly competitive research groups both on a national and international level, as well as pharmaceutical companies.

Research Lines

Networks

    CIBERobn Physiopathology of Obesity and Nutrition

    PAIDI CTS-525 Interaction genes and environment

    PAIDI CTS-212 Nutrition and disease

    NUTRIEPIGEN working group of Spanish researchers specialized in the arena of lifestyle and epigenetics

Keywords

  • Atherosclerosis
  • endothelium
  • metabolic syndrome
  • type 2 diabetes mellitus
  • Mediterranean diet
  • olive oil
  • polyphenols
  • antioxidants
  • inflammation
  • oxidative stress
  • cholesterol
  • polyphenols
  • gene expression
  • proteomics
  • nutrigenetics
  • nutrigenomics

GC09 Nutrigenomics. Metabolic Syndrome

Principal Investigator
José López Miranda

Co-Principal Investigators
Francisco Pérez Jiménez
Javier Delgado Lista
Pablo Pérez Martínez
Yolanda Almadén Peña

Emerging Researchers
Antonio Camargo García
Antonio García Ríos
Elena M. Yubero Serrano

Researchers
Mª Ángeles Blanco Molina
Rafael Ángel Fernández de la Puebla
Francisco Fuentes Jiménez
Luciano López Jiménez
Manuel Montero Pérez-Barquero
Anabel Pérez Caballero
Oriol Rangel-Zuñiga
Elena M Yubero-Serrano

Post-Doctoral Researchers
Juan Francisco Alcalá Díaz
Juan Criado García
Silvia de la Cruz Ares
Francisco Gómez-Delgado
Purificación Gómez Luna
Francisco Gutiérrez Mariscal
Anabel Jiménez Morales
Ana León Acuña
Irene Roncero Ramos

Pre-Doctoral Researchers
Antonio Pablo Arenas de Larriva
Carolina Fernández Gándara
Javier López Moreno
María Magdalena Pérez Cardelo
José David Torres Peña
Cristina Vals-Delgado
Ana María Vega Rojas
Alejandro Villasanta González

Technical and Administrative Staff
Rosario Carreras Calero
Begoña Díaz Marín
José Andrés Morales Martínez
Patricia Judith Peña Orihuela
Isabel Pérez Corral
Gracia Mª Quintana Navarro
Ana Redondo Garrido

Projects

Active Projects

Regional

Yubero Serrano, E.M.  Effect of the Consumption of Two Dietary Models on the Development of Diabetic Nephropathy. Cordiprev-Nediab study. Funding agency: Regional Ministry of Economy, Innovation, Science and Employment (CEICE). Reference: PC-0283-2017.

Roncero Ramos, I. The role of the alpha cell in the development of type 2 diabetes mellitus in the elderly people. Funding Agency: FIBICO. Reference: PI-0107-2018-FIB 

National

Lopez Miranda, J. – Camargo García, A. Effect of a Mediterranean diet rich in virgin olive oil on the risk and incidence of Type 2 Diabetes Mellitus: Cordioprev-direct study. Reference: AGL2015-67896-P

Pérez Jiménez, F. Mediterranean diet associated with probiotics improves the cognitive function in patients with mild cognitive impairment modulating the axis microbiota-gut-brain. Funding agency: National Institute of Health Carlos III (ISCIII). Reference: PI16/01777

Almadén Peña, Y. The influence of the Mineral Metabolism on Endothelial dysfunction in Metabolic Syndrome and Atherosclerosis. Modulation by the Mediterranean diet. Funding agency: National Institute of Health Carlos III (ISCIII). Reference: PI17/01024

García Rios, A. Importance of the selection of stable mutants and of persister variants in the expression of colistin heterorresistance in Klebsiella pneumoniae. Funding agency: National Institute of Health Carlos III (ISCIII). Reference: PI17/01183

Fuentes Jiménez, F. Determination of new predictors of coronary heart disease in asymptomatic patients with familial Hypercholesterolemia. Funding agency: National Institute of Health Carlos III (ISCIII). Reference: PI17/01320.

Lopez Miranda, J and Yubero Serrano, EM. Regression of recently diagnosed type 2 diabetes mellitus: effect of HDL functionality. Research Funding Prof. Dr. Miguel Vilardell. Funding Agency: Fundacion Española De Medicina Interna. Reference: MVILARDELL_01_2018  

Yubero Serrano, E.M. Influence of obesity on the progression of diabetic nephropathy. Consumption of two models of hearthealthy diet as a therapeutic strategy in the development of the disease. Funding agency: National Institute of Health Carlos III (ISCIII). Reference: PI18/01822.

Yubero Serrano, E.M. New biomarkers and therapeutic targets in breast and prostate cancer: molecular  mechanisms in the pathological interaction between obesity and cancer. Funding Agency: Asociación Española Contra el Cáncer. Reference: AECC 2018/01

Camargo García, A. Composición microbiana del intestino como herramienta predictiva del desarrollo de Diabetes Mellitus tipo 2. Funding agency: National Institute of Health Carlos III (ISCIII). Reference: DTS19/00007 

Camargo García, A. Papel de la microbiota intestinal en las diferencias en el desarrollo de enfermedad cardiovascular en función del género Funding agency: National Institute of Health Carlos III (ISCIII). Reference: PI19/00299              

International

Delgado Lista, J. POWER2DM - Predictive model-based decision support for diabetes patient empowerment. Funding Agency: European Commission H2020. Reference: PHC28-2015-001

López Miranda, J. FAME - Fatty Acid Metabolism - Interlinking Diet with Cardiometabolic Health. Funding agency: JPI HDHL: BIOMARKERS FOR NUTRITION AND HEALTH – MINECO 2016. Reference: ERA-HDHL BioNH 2016-001

Publications

Main Publications 2019

Diaz-Tocados JM, Rodriguez-Ortiz ME, Almaden Y, Pineda C, Martinez-Moreno JM, Herencia C, Vergara N, de Mier MVPR, Santamaria R, Rodelo-Haad C, Casado-Diaz A, Lorenzo V, Carvalho C, Frazao JM, Felsenfeld AJ, Richards WG, Aguilera-Tejero E, Rodriguez M, Lopez I and Munoz-Castaneda JR; Calcimimetics maintain bone turnover in uremic rats despite the concomitant decrease in parathyroid hormone concentration. KIDNEY INTERNATIONAL. 95. 5.  (1064-1078). DOI: 10.1016/j.kint.2018.12.015.
IF: 8,306
Q: 1   D: 1

Camargo A, Jimenez-Lucena R, Alcala-Diaz JF, Rangel-Zuniga OA, Garcia-Carpintero S, Lopez-Moreno J, Blanco-Rojo R, Delgado-Lista J, Perez-Martinez P, van Ommen B, Malagon MM, Ordovas JM, Perez-Jimenez F, Lopez-Miranda J. Postprandial endotoxemia may influence the development of type 2 diabetes mellitus: From the CORDIOPREV study. CLINICAL NUTRITION. 2019. 38. 2. 529-538. DOI:10.1016/j.clnu.2018.03.016.
IF: 6,402
Q: 1   D: 1

Corina A, Rangel-Zuniga OA, Jimenez-Lucena R, Alcala-Diaz JF, Quintana-Navarro G, Yubero-Serrano EM, Lopez-Moreno J, Delgado-Lista J, Tinahones F, Ordovas JM, Lopez-Miranda J, Perez-Martinez P. Low Intake of Vitamin E Accelerates Cellular Aging in Patients With Established Cardiovascular Disease: The CORDIOPREV Study. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2019. 74. 6. 770-777. DOI:10.1093/gerona/gly195.
IF: 4,711
Q: 1   D: 1

Santos-Marcos JA, Haro C, Vega-Rojas A, Alcala-Diaz JF, Molina-Abril H, Leon-Acuna A, Lopez-Moreno J, Landa BB, Tena-Sempere M, Perez-Martinez P, Lopez-Miranda J, Perez-Jimenez F, Camargo A. Sex Differences in the Gut Microbiota as Potential Determinants of Gender Predisposition to Disease. MOLECULAR NUTRITION & FOOD RESEARCH. 2019. 63. 7. DOI:10.1002/mnfr.201800870.
IF: 4,653
Q: 1   D: 1

Gomez-Delgado F, Alcala-Diaz JF, Leon-Acuna A, Lopez-Moreno J, Delgado-Lista J, Gomez-Marin B, Roncero-Ramos I, Yubero-Serrano EM, Rangel-Zuniga OA, Vals-Delgado C, Luque RM, Ordovas JM, Lopez-Miranda J, Perez-Martinez P. Apolipoprotein E genetic variants interact with Mediterranean diet to modulate postprandial hypertriglyceridemia in coronary heart disease patients: CORDIOPREV study. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 2019. 49. 8. DOI:10.1111/eci.13146.
IF: 2,784
Q: 1

Other Publications 2019

Solomon SD, McMurray JJV, Anand IS, Ge J, Lam CSP, Maggioni AP, Martinez F, Packer M, Pfeffer MA, Pieske B, Redfield MM, Rouleau JL, van Veldhuisen DJ, Zannad F, Zile MR, Desai AS, Claggett B, Jhund PS, Boytsov SA, Comin-Colet J, Cleland J, Dungen HD, Gon; Angiotensin-Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction. NEW ENGLAND JOURNAL OF MEDICINE. 384. 17. (1609-1620). DOI: 10.1056/NEJMoa1908655.
IF: 70,67
Q: 1   D: 1

Sayon-Orea C, Razquin C, Bullo M, Corella D, Fito M, Romaguera D, Vioque J, Alonso-Gomez AM, Warnberg J, Martinez JA, Serra-Majem L, Estruch R, Tinahones FJ, Lapetra J, Pinto X, Tur JA, Lopez-Miranda J, Bueno-Cavanillas A, Delgado-Rodriguez M, Matia-Martin P, Daimiel L, Sanchez VM, Vidal J, Vazquez C, Ros E, Ruiz-Canela M, Sorli JV, Castaner O, Fiol M, Navarrete-Munoz EM, Aros F, Gomez-Gracia E, Zulet MA, Sanchez-Villegas A, Casas R, Bernal-Lopez R, Santos-Lozano JM, Corbella E, Bouzas C, Garcia-Arellano A, Basora J, Asensio EM, Schroder H, Monino M, de la Hera MG, Tojal-Sierra L, Toledo E, Diaz-Lopez A, Goday A, Salas-Salvado J, Martinez-Gonzalez MA; Effect of a Nutritional and Behavioral Intervention on Energy-Reduced Mediterranean Diet Adherence Among Patients With Metabolic Syndrome: Interim Analysis of the PREDIMED-Plus Randomized Clinical Trial. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. 322. 15. (1486-1499). DOI: 10.1001/jama.2019.14630.
IF: 51,273.
Q: 1   D: 1

Roe MT, Li QH, Bhatt DL, Bittner VA, Diaz R, Goodman SG, Harrington RA, Jukema JW, Lopez-Jaramillo P, Lopes RD, Louie MJ, Moriarty PM, Szarek M, Vogel R, White HD, Zeiher AM, Baccara-Dinet MT, Steg PG, Schwartz GG. (ODYSSEY OUTCOMES Investigators). Risk Categorization Using New American College of Cardiology/American Heart Association Guidelines for Cholesterol Management and Its Relation to Alirocumab Treatment Following Acute Coronary Syndromes. CIRCULATION. 140. 19. (1578-1589). DOI: 10.1161/CIRCULATIONAHA.119.042551.
IF: 23,054
Q1  D1

Ellis KL, de Isla LP, Alonso R, Fuentes F, Watts GF, Mata P; Value of Measuring Lipoprotein(a) During Cascade Testing for Familial Hypercholesterolemia. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 73. 9. (1029-1039). DOI: 10.1016/j.jacc.2018.12.037.
IF: 18,639
Q: 1   D: 1

Salas-Salvado J, Diaz-Lopez A, Ruiz-Canela M, Basora J, Fito M, Corella D, Serra-Majem L, Warnberg J, Romaguera D, Estruch R, Vidal J, Martinez JA, Aros F, Vazquez C, Ros E, Vioque J, Lopez-Miranda J, Bueno-Cavanillas A, Tur JA, Tinahones FJ, Martin V, La; Effect of a Lifestyle Intervention Program With Energy-Restricted Mediterranean Diet and Exercise on Weight Loss and Cardiovascular Risk Factors: One-Year Results of the PREDIMED-Plus Trial. DIABETES CARE. 42. 5. (777-788). DOI: 10.2337/dc18-0836.
IF: 15,27
Q: 1   D: 1

Martinez-Gonzalez MA, Buil-Cosiales P, Corella D, Bullo M, Fito M, Vioque J, Romaguera D, Martinez JA, Warnberg J, Lopez-Miranda J, Estruch R, Bueno-Cavanillas A, Aros F, Tur JA, Tinahones F, Serra-Majem L, Martin V, Lapetra J, Vazquez C, Pinto X, Vidal J; Cohort Profile: Design and methods of the PREDIMED-Plus randomized trial. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 48. 2. (387-+). DOI: 10.1093/ije/dyy225.
IF: 7,339
Q: 1   D: 1

Gutierrez-Mariscal FM, Yubero-Serrano EM, Villalba JM, Lopez-Miranda J. Coenzyme Q(10): From bench to clinic in aging diseases, a translational review. CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION. 2019. 59. 14. 2240-2257. DOI:10.1080/10408398.2018.1442316.
IF: 6,704
Q: 1   D: 1

Papandreou C, Diaz-Lopez A, Babio N, Martinez-Gonzalez MA, Bullo M, Corella D, Fito M, Romaguera D, Vioque J, Alonso-Gomez AM, Warnberg J, Martinez AJ, Serra-Majem L, Estruch R, Fernandez-Garcia JC, Lapetra J, Pinto X, Tur JA, Garcia-Rios A, Bueno-Cavanil; Long Daytime Napping Is Associated with Increased Adiposity and Type 2 Diabetes in an Elderly Population with Metabolic Syndrome. JOURNAL OF CLINICAL MEDICINE. 8. 7. DOI: 10.3390/jcm8071053.
IF: 5,688
Q: 1   D: 1

Gulseth HL, Gjelstad IMF, Tiereny AC, McCarthy D, Lovegrove JA, Defoort C, Blaak EE, Lopez-Miranda J, Dembinska-Kiec A, Riserus U, Roche HM, Drevon CA, Birkeland KI; Effects of dietary fat on insulin secretion in subjects with the metabolic syndrome. EUROPEAN JOURNAL OF ENDOCRINOLOGY. 180. 5. (321-328). DOI: 10.1530/EJE-19-0022.
IF: 5,107
Q: 1

De Larriva APA, Alonso A, Norby FL, Roetker NS, Folsom AR; Circulating ceruloplasmin, ceruloplasmin-associated genes and the incidence of venous thromboembolism in the Atherosclerosis Risk in Communities study. JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 17. 5. (818-826). DOI: 10.1111/jth.14420.
IF: 4,662
Q: 1

Tresserra-Rimbau A, Castro-Barquero S, Vitelli-Storelli F, Becerra-Tomas N, Vazquez-Ruiz Z, Diaz-Lopez A, Corella D, Castaner O, Romaguera D, Vioque J, Alonso-Gomez AM, Warnberg J, Martinez JA, Serra-Majem L, Estruch R, Tinahones FJ, Lapetra J, Pinto X, Tur JA, Lopez-Miranda J, Garcia-Molina L, Delgado-Rodriguez M, Matia-Martin P, Daimiel L, Rubin-Garcia M, Vidal J, Galdon A, Ros E, Basterra-Gortari FJ, Babio N, Sorli JV, Hernaez A, Konieczna J, Notario-Barandiaran L, Tojal-Sierra L, Perez-Lopez J, Abete I, Alvarez-Perez J, Fernandez-Garcia JC, Santos-Lozano JM, Galera-Cusi A, Julibert A, Ruiz-Canela M, Martinez-Lacruz R, Perez-Vega KA, Galmes-Panades AM, Pastor-Polo C, Moreno-Rodriguez A, Gea A, Fito M, Lamuela-Raventos RM, Salas-Salvado J; Associations between Dietary Polyphenols and Type 2 Diabetes in a Cross-Sectional Analysis of the PREDIMED-Plus Trial: Role of Body Mass Index and Sex. ANTIOXIDANTS. 8. 11. DOI: 10.3390/antiox8110537.
IF: 4,52
Q: 1   D: 1

del Rio-Moreno M, Alors-Perez E, Gonzalez-Rubio S, Ferrin G, Reyes O, Rodriguez-Peralvarez M, Sanchez-Frias ME, Sanchez-Sanchez R, Ventura S, Lopez-Miranda J, Kineman RD, de la Mata M, Castano JP, Gahete MD, Luque RM; Dysregulation of the Splicing Machinery Is Associated to the Development of Nonalcoholic Fatty Liver Disease. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 104. 8. (3389-3402). DOI: 10.1210/jc.2019-00021.
IF: 5,605
Q: 1

Alvarez-Alvarez I, Martinez-Gonzalez MA, Sanchez-Tainta A, Corella D, Diaz-Lopez A, Fito M, Vioque J, Romaguera D, Martinez JA, Warnberg J, Lopez-Miranda J, Estruch R, Bueno-Cavanillas A, Aros F, Tur JA, Tinahones FJ, Serra-Majem L, Martin V, Lapetra J, F; Adherence to an Energy-restricted Mediterranean Diet Score and Prevalence of Cardiovascular Risk Factors in the PREDIMED-Plus: A Cross-sectional Study. REVISTA ESPANOLA DE CARDIOLOGIA. 72. 11. (925-934). DOI: 10.1016/j.rec.2018.08.010.
IF: 5,078
Q: 1

Santos-Marcos JA, Perez-Jimenez F, Camargo A. The role of diet and intestinal microbiota in the development of metabolic syndrome. JOURNAL OF NUTRITIONAL BIOCHEMISTRY. 2019. 70. 1-27. DOI:10.1016/j.jnutbio.2019.03.017.
IF: 4,414
Q: 1

Perez-Calahorra S, Laclaustra M, Marco-Benedi V, Lamiquiz-Moneo I, Pedro-Botet J, Plana N, Sanchez-Hernandez RM, Amor AJ, Almagro F, Fuentes F, Suarez-Tembra M, Civeira F; Effect of lipid-lowering treatment in cardiovascular disease prevalence in familial hypercholesterolemia. ATHEROSCLEROSIS. 284. (245-252). DOI: 10.1016/j.atherosclerosis.2019.02.003.
IF: 4,255
Q: 1

Masana L, Ibarretxe D, Rodriguez-Borjabad C, Plana N, Valdivielso P, Pedro-Botet J, Civeira F, Lopez-Miranda J, Guijarro C, Mostaza J, Pinto X; Toward a new clinical classification of patients with familial hypercholesterolemia: One perspective from Spain. ATHEROSCLEROSIS. 287. (89-92). DOI: 10.1016/j.atherosclerosis.2019.06.905.
IF: 4,255
Q: 1

Miramontes-Gonzalez JP, Usategui-Martin R, de Isla LP, Alonso R, Muniz-Grijalvo O, Diaz-Diaz JL, Zambon D, Jimenez FF, Martin-Vallejo J, Gude AER, Jimenez DL, Padro T, Gonzalez-Sarmiento R, Mata P; VEGFR2 and OPG genes modify the risk of subclinical coronary atherosclerosis in patients with familial hypercholesterolemia. ATHEROSCLEROSIS. 285. (17-22). DOI: 10.1016/j.atherosclerosis.2019.03.019.
IF: 4,255
Q: 1

Leon-Acuna A, Torres-Pena JD, Alcala-Diaz JF, Vals-Delgado C, Roncero-Ramos I, Yubero-Serrano E, Tinahones FJ, Castro-Clerico M, Delgado-Lista J, Ordovas JM, Lopez-Miranda J, Perez-Martinez P; Lifestyle factors modulate postprandial hypertriglyceridemia: From the CORDIOPREV study. ATHEROSCLEROSIS. 290. (118-124). DOI: 10.1016/j.atherosclerosis.2019.09.025.
IF: 4,255
Q: 1

Davila LA, Bermudez V, Aparicio D, Cespedes V, Escobar MC, Duran-Aguero S, Cisternas S, Costa JD, Rojas-Gomez D, Reyna N, Lopez-Miranda J. Effect of Oral Nutritional Supplements with Sucromalt and Isomaltulose versus Standard Formula on Glycaemic Index, Entero-Insular Axis Peptides and Subjective Appetite in Patients with Type 2 Diabetes: A Randomised Cross-Over Study. NUTRIENTS. 2019. 11. 7. DOI: 10.3390/nu11071477.
IF: 4,171
Q: 1

Cano-Ibanez N, Gea A, Martinez-Gonzalez MA, Salas-Salvado J, Corella D, Zomeno MD, Romaguera D, Vioque J, Aros F, Warnberg J, Martinez JA, Serra-Majem L, Estruch R, Tinahones FJ, Lapetra J, Pinto X, Tur JA, Garcia-Rios A, Riquelme-Gallego B, Delgado-Rodri; Dietary Diversity and Nutritional Adequacy among an Older Spanish Population with Metabolic Syndrome in the PREDIMED-Plus Study: A Cross-Sectional Analysis. NUTRIENTS. 11. 5. DOI: 10.3390/nu11050958.
IF: 4,171
Q: 1

Bibiloni MD, Julibert A, Bouzas C, Martinez-Gonzalez MA, Corella D, Salas-Salvado J, Zomeno MD, Vioque J, Romaguera D, Martinez JA, Warnberg J, Lopez-Miranda J, Estruch R, Bueno-Cavanillas A, Aros F, Tinahones F, Serra-Majem L, Martin V, Lapetra J, Vazque; Nut Consumptions as a Marker of Higher Diet Quality in a Mediterranean Population at High Cardiovascular Risk. NUTRIENTS. 11. 4. DOI: 10.3390/nu11040754.
IF: 4,171
Q: 1

Papandreou C, Babio N, Diaz-Lopez A, Martinez-Gonzalez MA, Becerra-Tomas N, Corella D, Schroder H, Romaguera D, Vioque J, Alonso-Gomez AM, Warnberg J, Martinez AJ, Serra-Majem L, Estruch R, Munoz-Garach A, Lapetra J, Pinto X, Tur JA, Garcia-Rios A, Bueno-; Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk. NUTRIENTS. 11. 4. DOI: 10.3390/nu11040761.
IF: 4,171
Q: 1

Julibert A, Bibiloni MD, Bouzas C, Martinez-Gonzalez MA, Salas-Salvado J, Corella D, Zomeno MD, Romaguera D, Vioque J, Alonso-Gomez AM, Warnberg J, Martinez JA, Serra-Majem L, Estruch R, Tinahones FJ, Lapetra J, Pinto X, Lopez-Miranda J, Garcia-Molina L, ; Total and Subtypes of Dietary Fat Intake and Its Association with Components of the Metabolic Syndrome in a Mediterranean Population at High Cardiovascular Risk. NUTRIENTS. 11. 7. DOI: 10.3390/nu11071493.
IF: 4,171
Q: 1

Ditano-Vazquez P, Torres-Pena JD, Galeano-Valle F, Perez-Caballero AI, Demelo-Rodriguez P, Lopez-Miranda J, Katsiki N, Delgado-Lista J, Alvarez-Sala-Walther LA; The Fluid Aspect of the Mediterranean Diet in the Prevention and Management of Cardiovascular Disease and Diabetes: The Role of Polyphenol Content in Moderate Consumption of Wine and Olive Oil. NUTRIENTS. 11. 11. DOI: 10.3390/nu11112833.
IF: 4,171
Q: 1

Clemente-Postigo M, Oliva-Olivera W, Coin-Araguez L, Ramos-Molina B, Giraldez-Perez RM, Lhamyani S, Alcaide-Torres J, Perez-Martinez P, El Bekay R, Cardona F, Tinahones FJ; Metabolic endotoxemia promotes adipose dysfunction and inflammation in human obesity. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 316. 2 (E319-E332). DOI: 10.1152/ajpendo.00277.2018.
IF: 4,125
Q: 1

Rodriguez-Ortiz ME, Gomez-Delgado F, de Larriva APA, Canalejo A, Gomez-Luna P, Herencia C, Lopez-Moreno J, Rodriguez M, Lopez-Miranda J, Almaden Y. Serum Magnesium is associated with Carotid Atherosclerosis in patients with high cardiovascular risk (CORDIOPREV Study). SCIENTIFIC REPORTS. 2019. 9. DOI:10.1038/s41598-019-44322-z.
IF: 4,011
Q: 1

Llacer P, Nunez J, Bayes-Genis A, Martel AC, Hernandez YC, Manglano JD, Rocha PA, Rangel LS, Del Olmo VG, Manzano L, Perez-Barquero MM. Digoxin and prognosis of heart failure in older patients with preserved ejection fraction: Importance of heart rate. Results from an observational and multicenter study. EUROPEAN JOURNAL OF INTERNAL MEDICINE. 2019. 60. 18-23. DOI:10.1016/j.ejim.2018.10.010.
IF: 3,66
Q: 1

Formiga F, Chivite D, Corbella X, Conde-Martel A, Arevalo-Lorido JC, Trullas JC, Silvestre JP, Garcia SC, Manzano L, Montero-Perez-Barquero M (Rica Investigators Grp: Alvarez-Rocha P, Anarte L, Aramburu-Bodas O, Carrascosa S, Casado J, Cerqueiro JM, Diez-. Influence of potassium levels on one-year outcomes in elderly patients with acute heart failure. EUROPEAN JOURNAL OF INTERNAL MEDICINE. 2019. 60. 24-30. DOI:10.1016/j.ejim.2018.10.016.
IF: 3,66
Q: 1

Quiros-Lopez R, Manzano-Espinosa L, Bilbao A, Perez-Barquero M, Cepeda-Rodrigo JM, Escobar-Martinez A; External validation of the CACE-HF risk score for mortality in patients with heart failure. EUROPEAN JOURNAL OF INTERNAL MEDICINE. 66. (35-40). DOI: 10.1016/j.ejim.2019.05.010.
IF: 3,66
Q: 1

Lopez-Bascon MA, Calderon-Santiago M, Diaz-Lozano A, Camargo A, Lopez-Miranda J, Priego-Capote F; Development of a qualitative/quantitative strategy for comprehensive determination of polar lipids by LC-MS/MS in human plasma. ANALYTICAL AND BIOANALYTICAL CHEMISTRY. DOI: 10.1007/s00216-019-02261-8.
IF: 3,286
Q: 1

de Isla LP, Arroyo-Olivares R, Muniz-Grijalvo O, Diaz-Diaz JL, Zambon D, Fuentes F, Munoz-Torrero JFS, Mediavilla JD, Gonzalez-Estrada A, Miramontes-Gonzalez JP, de Andres R, Mauri M, Mosquera D, Cepeda JM, Suarez L, Barba-Romero MA, Argueso R, Alvarez-Banos P, Michan A, Romero-Jimenez MJ, Garcia-Cruces J, Padro T, Alonso R, Mata P; Long-term effect of 2 intensive statin regimens on treatment and incidence of cardiovascular events in familial hypercholesterolemia: The SAFEHEART study. JOURNAL OF CLINICAL LIPIDOLOGY. 13. 6. (989-996). DOI: 10.1016/j.jacl.2019.10.005.
IF: 3,581
Q: 2

Yubero-Serrano EM, Lopez-Moreno J, Gomez-Delgado F, Lopez-Miranda J. Extra virgin olive oil: More than a healthy fat. EUROPEAN JOURNAL OF CLINICAL NUTRITION. 2019. 72. S. 8-17. DOI:10.1038/s41430-018-0304-x.
IF: 3,114
Q: 2

Antoniazzi L, Arroyo-Olivares R, Bittencourt MS, Tada MT, Lima I, Jannes CE, Krieger JE, Pereira AC, Quintana-Navarro G, Muniz-Grijalvo O, Diaz-Diaz JL, Zambon D, Mata P, Santos RD; Association of dietary components with dyslipidemia and low-grade inflammation biomarkers in adults with heterozygous familial hypercholesterolemia from different countries. EUROPEAN JOURNAL OF CLINICAL NUTRITION. 73. 12. (1622-1625). DOI: 10.1038/s41430-019-0529-3.
IF: 3,114
Q: 2

Kolovou GD, Watts GF, Mikhailidis DP, Perez-Martinez P, Mora S, Bilianou H, Panotopoulos G, Katsiki N, Ooi TC, Lopez-Miranda J, Tybjaerg-Hansen A, Tentolouris N, Nordestgaard BG; Postprandial Hypertriglyceridaemia Revisited in the Era of Non-Fasting Lipid Profile Testing: A 2019 Expert Panel Statement, Main Text. CURRENT VASCULAR PHARMACOLOGY. 17. 5. (498-514). DOI: 10.2174/1570161117666190507110519.
IF: 2,583
Q: 2

Kolovou GD, Watts GF, Mikhailidis DP, Perez-Martinez P, Mora S, Mora S, Bilianou H, Panotopoulos G, Katsiki N, Ooi TC, Lopez-Miranda J, Tybjaerg-Hansen A, Tentolouris N, Nordestgaard BG; Postprandial Hypertriglyceridaemia Revisited in the Era of Non-Fasting Lipid Profile Testing: A 2019 Expert Panel Statement, Narrative Review. CURRENT VASCULAR PHARMACOLOGY. 17. 5. (515-537). DOI: 10.2174/1570161117666190503123911.
IF: 2,583
Q: 2

Pedro-Botet J, Lopez-Miranda J, Badimon L, Civeira F, Guijarro C, Millan J, Mostaza JM, Pinto X, Valdivielso P, Masana L; Overall Mortality and LDL Cholesterol Reduction in Secondary Prevention Trials of Cardiovascular Disease. AMERICAN JOURNAL OF CARDIOVASCULAR DRUGS. DOI: 10.1007/s40256-019-00376-y.
IF: 2,578
Q: 2

Arroyo-Olivares R, Alonso R, Quintana-Navarro G, Fuentes-Jimenez F, Mata N, Muniz-Grijalvo O, Diaz-Diaz JL, Zambon D, Arrieta F, Garcia-Cruces J, Garrido-Sanjuan JA, Banegas JR, Mata P; Adults with familial hypercholesterolaemia have healthier dietary and lifestyle habits compared with their non-affected relatives: the SAFEHEART study. PUBLIC HEALTH NUTRITION. 22. 8. (1433-1443). DOI: 10.1017/S1368980018003853.
IF: 2,526
Q: 2

Trullas JC, Casado J, Morales-Rull JL, Formiga F, Conde-Martel A, Quiros R, Epelde F, Gonzalez-Franco A, Manzano L, Montero-Perez-Barquero M. Prevalence and outcome of diuretic resistance in heart failure. INTERNAL AND EMERGENCY MEDICINE. 2019. 14. 4. 529-537. DOI: 10.1007/s11739-018-02019-7.
IF: 2,335
Q: 2

Catoi AF, Vodnar DC, Corina A, Nikolic D, Citarrella R, Perez-Martinez P, Rizzo M; Gut Microbiota, Obesity and Bariatric Surgery: Current Knowledge and Future Perspectives. CURRENT PHARMACEUTICAL DESIGN. 25. 18. (2038-2050). DOI: 10.2174/1381612825666190708190437.
IF: 2,412
Q: 3

Corina A, Abrudan MB, Nikolic D, Catoi AF, Chianetta R, Castellino G, Citarrella R, Stoian AP, Perez-Martinez P, Rizzo, M; Effects of Aging and Diet on Cardioprotection and Cardiometabolic Risk Markers. CURRENT PHARMACEUTICAL DESIGN. 25. 35. (3704-3714). DOI: 10.2174/1381612825666191105111232.
IF: 2,412
Q: 3

Huerta-Preciado J, Franco J, Formiga F, Iborra PL, Epelde F, Franco AG, Ormaechea G, Manzano L, Cepeda-Rodrigo JM, Montero-Perez-Barquero M. With the Aid of RICA Investigators Group: Rocha, PA; Anarte, L; Arevalo-Lorido, JC; Cabanes, Y; Carrascosa, S; Izq. Differential characteristics of acute heart failure in very elderly patients: the prospective RICA study. AGING CLINICAL AND EXPERIMENTAL RESEARCH. 2019. DOI: 10.1007/s40520-019-01363-8.
IF: 2,331
Q: 3

Garcia-Hernandez FJ, Castillo-Palma MJ, Tolosa-Vilella C, Guillen-del Castillo A, Rubio-Rivas M, Freire M, Vargas-Hitos JA, Todoli-Parra JA, Rodriguez-Carballeira M, Espinosa-Garriga G, Colunga-Arguelles D, Ortego-Centeno N, Trapiella-Martinez L, Rodero-R; Pulmonary hypertension in Spanish patients with systemic sclerosis. Data from the RESCLE registry. CLINICAL RHEUMATOLOGY. 38. 4.  (1117-1124). DOI: 10.1007/s10067-018-4390-x.
IF: 2,293
Q: 3

Kolovou GD, Watts GF, Mikhailidis DP, Perez-Martinez P, Mora S, Bilianou H, Panotopoulos G, Katsiki N, Ooi TC, Lopez-Miranda J, Tybjaerg-Hansen A, Tentolouris N, Nordestgaard BG; Postprandial Hypertriglyceridaemia Revisited in the Era of Non-fasting Lipid Profiles: Executive Summary of a 2019 Expert Panel Statement. CURRENT VASCULAR PHARMACOLOGY. 17. 5. (538-540). DOI: 10.2174/1570161117999190517115432.
IF: 2,087
Q: 3

Franco J, Formiga F, Corbella X, Conde-Martel A, Llacer P, Rocha PA, Gorricho GO, Satue J, Rangel LS, Manzano L, Montero-Perez-Barquero M. (Grp Invest RICA: Anarte L, Aramburu O, Arevalo-Lorido JC, Carrascosa S, Carrera M, Cepeda JM, Cerqueiro JM, Davila . De novo acute heart failure: Clinical features and one-year mortality in the Spanish nationwide Registry of Acute Heart Failure. MEDICINA CLINICA. 2019. 152. 4. 127-134. DOI:10.1016/j.medcli.2018.05.012.
IF: 1,277
Q: 3

Montero-Perez-Barquero M, Manzano L. Quality of life, compliance and satisfaction of patients with atrial fibrillation who are undergoing anticoagulant treatment. REVISTA CLINICA ESPANOLA. 2019. 219. 6. 320-321. DOI:10.1016/j.rce.2019.03.002.
IF: 1,184
Q: 3

Amoros JG, Formiga F, Bodas OA, Arxe AA, Martel AC, Simon MAQ, Juanes RO, Bartolome JAS, Ramos MFD, Perez-Barquero MM. Hemoconcentration as a prognostic factor after hospital discharge in acute heart failure in the RICA registry. REVISTA CLINICA ESPANOLA. 2019. 219. 1. 1-9. DOI:10.1016/j.rce.2018.07.003.
IF: 1,043
Q: 3

Chivite D, Franco J, Formiga F, Salamanca-Bautista P, Manzano L, Conde-Martel A, Arevalo-Lorido JC, Suarez-Pedreira I, Casado-Cerrada J, Montero-Perez-Barquero M. The short-term prognostic value of C-reactive protein in elderly patients with acute heart failure. REVISTA CLINICA ESPANOLA. 2019. 219. 1. 10-17. DOI:10.1016/j.rce.2018.04.019.
IF: 1,043
Q: 3

Ruiz-Ruiz F, Medrano FJ, Santos-Lozano JM, Rodriguez-Torres P, Navarro-Puerto A, Calderon EJ, del Rio CAO, Marin-Leon I, Romero-Alonso A, Varela-Aguilar JM, Martinez MNB, Molina MAB, Vales EC, Montoro AE, Dalmau FGB, Hernandez AL, Rodriguez JAN, Santos JT; Anticoagulant treatment of medical patients with complex clinical conditions. REVISTA CLINICA ESPANOLA. 219. 1. (34-43). DOI: 10.1016/j.rce.2018.04.007.
IF: 1,043
Q: 3

 Bernabeu-Wittel M, Diez-Manglano J, Nieto-Martin D, Ramirez-Duque N, Ollero-Baturone M.  en representación de los investigadores del Proyecto PROFUND; Investigadores del Proyecto PROFUND: Abella-Vazquez, L; Aguayo-Canela, M; Albert-Coll, M; Aleman, A; Ali; Simplification of the Barthel scale for screening for frailty and severe dependency in polypathological patients. REVISTA CLINICA ESPANOLA. 2019. 8. (433-439). DOI: 10.1016/j.rce.2019.04.005.
IF: 1,043
Q: 3

Arevalo-Lorido JC, Carretero-Gomez J, Robles NR, Llacer P, Carrera M, Suarez-Pedreira I, Alvarez-Rocha P, Manzano-Espinosa L, Cepeda-Rodrigo JM, Montero-Perez-Barquero M. (on behalf of the RICA Investigators Group. Rocha, PA; Anarte, L; Arevalo-Lorido, JC. Prognostic Role of Hyponatremia in Heart Failure Patients Depending on Renal Disease: Clinical Evidence. CARDIOLOGY. 2019. 144. 1-2. 1-8. DOI: 10.1159/000502566  
IF: 1,561
Q: 4

Garcia-Rios A, Garcia AC, Perez-Jimenez F, Perez-Martinez P. Gut microbiota: Anew protagonist in the risk of cardiovascular disease?. CLINICA E INVESTIGACION EN ARTERIOSCLEROSIS. 2019. 31. 4. 178-185. DOI:10.1016/j.arteri.2018.11.003.
IF: 0

Perez-Martinez P, Huelgas RG, Perez-Jimenez F. Healthy planetary diet: do we have to rethink the recommendations based on the Mediterranean diet?. CLINICA E INVESTIGACION EN ARTERIOSCLEROSIS. 2019. 31. 5. 218-221. DOI:10.1016/j.arteri.2019.09.001.
IF: 0

Sanchez-Chaparro MA, Perez-Martinez P, Ibarretxe D, Suarez-Tembra M, Valdivielso P, Ros E, Martinez S, Cenarro A, Sanchez MA, Ibarretxe D, Suarez M, Muniz O, Perez P, Blanco A, Vea A, Toro R, Serra E, Romero MJ, Rodriguez C, Pardo A, Marquez L, de los San; Criteria for referring patients to Spanish Atherosclerosis Society lipid units. CLINICA E INVESTIGACION EN ARTERIOSCLEROSIS. 31. 1. (26-30). DOI: 10.1016/j.arteri.2018.04.005.
IF: 0  

Ascaso JF, Civeira F, Guijarro C, Miranda JL, Masana L, Mostaza JM, Pedro-Botet J, Pinto X, Valdivielso P; Indications of PCSK9 inhibitors in clinical practice. Recommendations of the Spanish Sociey of Arteriosclerosis (SEA), 2019. CLINICA E INVESTIGACION EN ARTERIOSCLEROSIS. 31. 3.  (128-139). DOI: 10.1016/j.arteri.2019.04.002.
IF: 0

 Pascual V, Martinez PP, Fernandez JM, Sola R, Pallares V, Secin AR, Jimenez FP, Ros E; SEA/SEMERGEN consensus document 2019: Dietary recommendations in the prevention of cardiovascular disease. CLINICA E INVESTIGACION EN ARTERIOSCLEROSIS. 31. 4. (186-201). DOI: 10.1016/j.arteri.2019.02.004.
IF: 0

Main Publications 2018

Gomez-Marin B, Gomez-Delgado F, Lopez-Moreno J, Alcala-Diaz JF, Jimenez-Lucena R, Torres-Pena JD, Garcia-Rios A, Ortiz-Morales AM, Yubero-Serrano EM, Malagon MD, Lai CQ, Delgado-Lista J, Ordovas JM, Lopez-Miranda J, Perez-Martinez P. Long-term consumption of a Mediterranean diet improves postprandial lipemia in patients with type 2 diabetes: the Cordioprev randomized trial. AMERICAN JOURNAL OF CLINICAL NUTRITION. 2018; 108(5):963-970.
IF: 6,549  
Q: 1   D: 1

Garcia-Rios A, Alcala-Diaz JF, Gomez-Delgado F, Delgado-Lista J, Marin C, Leon-Acuna A, Camargo A, Rodriguez-Cantalejo F, Blanco-Rojo R, Quintana-Navarro G, Ordovas JM, Perez-Jimenez F, Lopez-Miranda J, Perez-Martinez P. Beneficial effect of CETP gene polymorphism in combination with a Mediterranean diet influencing lipid metabolism in metabolic syndrome patients: CORDIOPREV study. CLINICAL NUTRITION. 2018; 37(1):229-234.
IF: 5,496  
Q: 1   D: 1

Roncero-Ramos I, Rangel-Zuniga OA, Lopez-Moreno J, Alcala-Diaz JF, Perez-Martinez P, Jimenez-Lucena R, Castano JP, Roche HM, Delgado-Lista J, Ordovas JM, Camargo A, Lopez-Miranda J. Mediterranean Diet, Glucose Homeostasis, and Inflammasome Genetic Variants: The CORDIOPREV Study. MOLECULAR NUTRITION & FOOD RESEARCH. 2018; 62(9):Núm artículo 1700960
IF: 5,151  
Q: 1   D: 1

Gomez-Delgado F, Delgado-Lista J, Lopez-Moreno J, Rangel-Zuniga OA, Alcala-Diaz JF, Leon-Acuna A, Corina A, Yubero-Serrano E, Torres-Pena JD, Camargo A, Garcia-Rios A, Caballero J, Castano J, Ordovas JM, Lopez-Miranda J, Perez-Martinez P. Telomerase RNA Component Genetic Variants Interact With the Mediterranean Diet Modifying the Inflammatory Status and its Relationship With Aging: CORDIOPREV Study. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2018; 73(3):327-332.
IF: 4,902  
Q: 1   D: 1

Lopez-Moreno J, Quintana-Navarro GM, Delgado-Lista J, Garcia-Rios A, Alcala-Diaz JF, Gomez-Delgado F, Camargo A, Perez-Martinez P, Tinahones FJ, Striker GE, Perez-Jimenez F, Villalba JM, Lopez-Miranda J, Yubero-Serrano EM. Mediterranean Diet Supplemented With Coenzyme Q(10) Modulates the Postprandial Metabolism of Advanced Glycation End Products in Elderly Men and Women. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2018; 73(3):340-346.
IF: 4,902  
Q: 1   D: 1

Other Publications 2018

Jimenez-Lucena R, Rangel-Zuniga OA, Alcala-Diaz JF, Lopez-Moreno J, Roncero-Ramos I, Molina-Abril H, Yubero-Serrano EM, Caballero-Villarraso J, Delgado-Lista J, Castano JP, Ordovas JM, Perez-Martinez P, Camargo A, Lopez-Miranda J. Circulating miRNAs as Predictive Biomarkers of Type 2 Diabetes Mellitus Development in Coronary Herat Disease Patients from the CORDIOPREV Study. MOLECULAR THERAPY-NUCLEIC ACIDS. 2018; 12:146-157.
IF: 5,66  
Q: 1   D: 1

Jimenez-Lucena R, Camargo A, Alcala-Diaz JF, Romero-Baldonado C, Luque RM, van Ommen B, Delgado-Lista J, Ordovas JM, Perez-Martinez P, Rangel-Zuniga OA, Lopez-Miranda J. A plasma circulating miRNAs profile predicts type 2 diabetes mellitus and prediabetes: from the CORDIOPREV study. EXPERIMENTAL AND MOLECULAR MEDICINE. 2018; 50:Núm artículo 168
IF: 5,584  
Q: 1

Roncero-Ramos I, Jimenez-Lucena R, Alcala-Diaz JF, Vals-Delgado C, Arenas-Larriva AP, Rangel-Zuniga OA, Leon-Acuna A, Malagon MM, Delgado-Lista J, Perez-Martinez P, Ordovas JM, Camargo A, Lopez-Miranda J. Alpha cell function interacts with diet to modulate prediabetes and Type 2 diabetes. JOURNAL OF NUTRITIONAL BIOCHEMISTRY. 2018; 62:247-256.
IF: 4,414  
Q: 1

Torres-Pena JD, Garcia-Rios A, Delgado-Casado N, Gomez-Luna P, Alcala-Diaz JF, Yubero-Serrano EM, Gomez-Delgado F, Leon-Acuna A, Lopez-Moreno J, Camargo A, Tinahones FJ, Delgado-Lista J, Ordovas JM, Perez-Martinez P, Lopez-Miranda J. Mediterranean diet improves endothelial function in patients with diabetes and prediabetes: A report from the CORDIOPREV study. ATHEROSCLEROSIS. 2018; 269:50-56.
IF: 4,467  
Q: 1

Santos-Marcos, JA; Rangel-Zuniga, OA; Jimenez-Lucena, R; Quintana-Navarro, GM; Garcia-Carpintero, S; Malagon, MM; Landa, BB; Tena-Sempere, M; Perez-Martinez, P; Lopez-Miranda, J; Perez-Jimenez, F; Camargo, A. Influence of gender and menopausal status on gut microbiota. MATURITAS. 2018; 116:43-53.
IF: 3,315  
Q: 1

Chivite D, Formiga F, Corbella X, Conde-Martel A, Aramburu O, Carrera M, Davila MF, Perez-Silvestre J, Manzano L, Montero-Perez-Barquero M. Basal functional status predicts one-year mortality after a heart failure hospitalization in elderly patients - The RICA prospective study. INTERNATIONAL JOURNAL OF CARDIOLOGY. 2018; 254:182-188.
IF: 4,034  
Q: 2

Guisado-Espartero ME, Salamanca-Bautista P, Aramburu-Bodas O, Conde-Martel A, Arias-Jimenez JL, Llacer-Iborra P, Davila-Ramos MF, Cabanes-Hernandez Y, Manzano L, Montero-Perez-Barquero M. Heart failure with mid-range ejection fraction in patients admitted to internal medicine departments: Findings from the RICA Registry. INTERNATIONAL JOURNAL OF CARDIOLOGY. 2018; 255:124-128.
IF: 4,034  
Q: 2

Lopez-Moreno J, Garcia-Carpintero S, Gomez-Delgado F, Jimenez-Lucena R, Vals-Delgado C, Alcala-Diaz JF, Roncero-Ramos I, Rangel-Zuniga OA, Yubero-Serrano EM, Malagon MM, Ordovas JM, Perez-Martinez P, Lopez-Miranda J, Camargo A. Endotoxemia is modulated by quantity and quality of dietary fat in older adults. EXPERIMENTAL GERONTOLOGY. 2018; 109:119-125.
IF: 3,224   
Q: 2

Garcia-Rios A, Ordovas JM, Lopez-Miranda J, Perez-Martinez P. New diet trials and cardiovascular risk. CURRENT OPINION IN CARDIOLOGY. 2018; 33(4):423-428.
IF: 2,006  
Q: 3

Franco J, Formiga F, Cepeda J, Llacer P, Arevalo-Lorido J, Cerqueiro J, Gonzalez-Franco A, Epelde F, Manzano L, Perez-Barquero MM. Influence of atrial fibrillation on the mortality of patients with heart failure with preserved ejection fraction. MEDICINA CLINICA. 2018; 150(10):376-382.
IF: 1,168  
Q: 3

Sanchez-Garcia ME, Ramirez-Lara I, Gomez-Delgado F, Yubero-Serrano EM, Leon-Acuna A, Marin C, Alcala-Diaz JF, Camargo A, Lopez-Moreno J, Perez-Martinez P, Tinahones FJ, Ordovas JM, Caballero J, Blanco-Molina A, Lopez-Miranda J, Delgado-Lista J. Quantitative evaluation of capillaroscopic microvascular changes in patients with established coronary heart disease. MEDICINA CLINICA. 2018; 150(4):131-137.
IF: 1,168  
Q: 3

Perez-Jimenez F, Pascual V, Meco JF, Martinez PP, Lista JD, Domenech M, Estruch R, Leon-Acuna A, Lopez-Miranda J, Sanchez-Ramos A, Ferrer CSI, Soler-Rivas C, Alberich RMS, Valdivielso P, Ros E. Document of recommendations of the SEA 2018. Lifestyle in cardiovascular prevention. CLINICA E INVESTIGACION EN ARTERIOSCLEROSIS. 2018; 30(6):280-310.
IF: 0

Martin SS, Giugliano RP, Murphy SA, Wasserman SM, Stein EA, Ceska R, Lopez-Miranda J, Georgiev B, Lorenzatti AJ, Tikkanen MJ, Sever PS, Keech AC, Pedersen TR, Sabatine MS. Comparison of Low-Density Lipoprotein Cholesterol Assessment by Martin/Hopkins Estimation, Friedewald Estimation, and Preparative Ultracentrifugation Insights From the FOURIER Trial. JAMA CARDIOLOGY. 2018; 3(8):749-753.
IF: 10,133  
Q: 1   D: 1

Gahete MD, del Rio-Moreno M, Camargo A, Alcala-Diaz JF, Alois-Perez E, Delgado-Lista J, Reyes O, Ventura S, Perez-Martinez P, Castno JP, Lopez-Miranda J, Luque RM. Changes in Splicing Machinery Components Influence, Precede, and Early Predict the Development of Type 2 Diabetes: From the CORDIOPREV Study. EBIOMEDICINE. 2018; 37:356-365.
IF: 6,183  
Q: 1   D: 1

Schroder H, Cardenas-Fuentes G, Martinez-Gonzalez MA, Corella D, Vioque J, Romaguera D, Martinez JA, Tinahones FJ, Miranda JL, Estruch R, Bueno-Cavanillas A, Aros F, Marcos A, Tur JA, Warnberg J, Serra-Majem L, Martin V, Vazquez C, Lapetra J, Pinto X, Vidal J, Daimiel L, Gaforio JJ, Matia-Martin P, Ros E, Castaner O, Lassale C, Ruiz-Canela M, Asensio EM, Basora J, Torres-Collado L, Garcia-Rios A, Abete I, Toledo E, Buil-Cosiales P, Bullo M, Goday A, Fito M, Salas-Salvado J. Effectiveness of the physical activity intervention program in the PREDIMED-Plus study: a randomized controlled trial. INTERNATIONAL JOURNAL OF BEHAVIORAL NUTRITION AND PHYSICAL ACTIVITY. 2018; 15:Núm artículo 110
IF: 5,548  
Q: 1   D: 1

Grandone E, Di Micco PP, Villani M, Colaizzo D, Fernandez-Capitan C, Del Toro J, Rosa V, Bura-Riviere A, Quere I, Blanco-Molina A, Margaglione M, Monreal M. Venous Thromboembolism in Women Undergoing Assisted Reproductive Technologies: Data from the RIETE Registry. THROMBOSIS AND HAEMOSTASIS. 2018; 118(11):1962-1968.
IF: 4,952  
Q: 1   D: 1

Rosique-Esteban N, Papandreou C, Romaguera D, Warnberg J, Corella D, Martinez-Gonzalez MA, Diaz-Lopez A, Estruch R, Vioque J, Aros F, Garcia-Rios A, Bueno-Cavanillas A, Vidal J, Serra-Majem L, Sibai AA, Tinahones FJ, Martinez A, Ordovas JM, Tur JA, Ellacuria MT, Sanllorente A, Pinto X, Buil-Cosiales P, Fernandez-Carrion R, Castaner O, Bullo M, Ruiz-Canela M, Garcia-de la Hera M, Perez-Farinos N, Baron-Lopez FJ, Colom A, Abete I, Ros E, Salas-Salvado J. Cross-sectional associations of objectively-measured sleep characteristics with obesity and type 2 diabetes in the PREDIMED-Plus trial. SLEEP. 2018; 41(12):Núm artículo UNSP zsy190.
IF: 5,137  
Q: 1

Brenner B, Bikdeli B, Tzoran I, Madridano O, Lopez-Reyes R, Surinach JM, Blanco-Molina A, Tufano A, Nunez JJL, Trujillo-Santos J, Monreal M. Arterial Ischemic Events Are a Major Complication in Cancer Patients with Venous Thromboembolism. AMERICAN JOURNAL OF MEDICINE. 2018; 131(9):1095-1103.
IF: 5,117  
Q: 1

Sanchez-Hernandez RM, Prieto-Matos P, Civeira F, Lafuente EE, Vargas MF, Real JT, Goicoechea FG, Fuentes FJ, Pocovi M, Boronat M, Wagner AM, Masana L. Autosomal recessive hypercholesterolemia in Spain. ATHEROSCLEROSIS. 2018; 269:1-5.
IF: 4,467  
Q: 1

Mari-Alfonso B, Simeon-Aznar CP, Guillen-Del Castillo A, Rubio-Rivas M, Trapiella-Martinez L, Todoli-Parra JA, Carballeira MR, Marin-Ballve A, Iniesta-Arandia N, Colunga-Arguelles D, Castillo-Palma MJ, Saez-Comet L, Egurbide-Arberas MV, Ortego-Centeno N, Freire M, Hitos JAV, Chamorro AJ, Madronero-Vuelta AB, Perales-Fraile I, Pla-Salas X, Fernandez-De-La-Puebla RA, Fonollosa-Pla V, Tolosa-Vilella C. Hepatobiliary involvement in systemic sclerosis and the cutaneous subsets: Characteristics and survival of patients from the Spanish RESCLE Registry. SEMINARS IN ARTHRITIS AND RHEUMATISM. 2018; 47(6):849-857.
IF: 4,356  
Q: 1

Cano-Ibanez N, Bueno-Cavanillas A, Martinez-Gonzalez MA, Corella D, Salas-Salvado J, Zomeno MD, Garcia-de-la-Hera M, Romaguera D, Martinez JA, Baron-Lopez FJ, Garcia-Rios A, Estruch R, Garcia-Molina L, Gomez AA, Tur JA, Tinahones F, Serra-Majem L, Cubelos-Fernandez N, Lapetra J, Vazquez C, Pinto X, Vidal J, Daimiel L, Juan Gaforio J, Matia P, Ros E, Diez-Espino J, Fernandez-Carrion R, Basora J, Fito M, Zazo JM, Colom A, Toledo E, Diaz-Lopez A, Munoz MA, Ruiz-Canela M, Gea A. Dietary Intake in Population with Metabolic Syndrome: Is the Prevalence of Inadequate Intake Influenced by Geographical Area? Cross-Sectional Analysis from PREDIMED-Plus Study. NUTRIENTS. 2018; 10(11):Núm artículo 1661
IF: 4 ,196  
Q: 1

Sanchez-Villegas A, Alvarez-Perez J, Toledo E, Salas-Salvado J, Ortega-Azorin C, Zomeno MD, Vioque J, Martinez JA, Romaguera D, Perez-Lopez J, Lopez-Miranda J, Estruch R, Bueno-Cavanillas A, Aros F, Tur JA, Tinahones FJ, Lecea O, Martin V, Ortega-Calvo M, Vazquez C, Pinto X, Vidal J, Daimiel L, Delgado-Rodriguez M, Matia P, Corella D, Diaz-Lopez A, Babio N, Munoz MA, Fito M, de la Hera MG, Abete I, Garcia-Rios A, Ros E, Ruiz-Canela M, Martinez-Gonzalez MA, Izquierdo M, Serra-Majem L. Seafood Consumption, Omega-3 Fatty Acids Intake, and Life-Time Prevalence of Depression in the PREDIMED-Plus Trial. NUTRIENTS. 2018; 10(12):Núm artículo 2000
IF:  4,196  
Q: 1

Mallorqui-Bague N, Lozano-Madrid M, Toledo E, Corella D, Salas-Salvado J, Cuenca-Royo A, Vioque J, Romaguera D, Martinez JA, Warnberg J, Lopez-Miranda J, Estruch R, Bueno-Cavanillas A, Alonso-Gomez A, Tur JA, Tinahones FJ, Serra-Majem L, Martin V, Lapetra J, Vazquez C, Pinto X, Vidal J, Daimiel L, Gaforio JJ, Matia P, Ros E, Granero R, Buil-Cosiales P, Barragan R, Bullo M, Castaner O, Garcia-de-la-Hera M, Yanez AM, Abete I, Garcia-Rios A, Ruiz-Canela M, Diaz-Lopez A, Jimenez-Murcia S, Martinez-Gonzalez MA, De la Torre R, Fernandez-Aranda F. Type 2 diabetes and cognitive impairment in an older population with overweight or obesity and metabolic syndrome: baseline cross-sectional analysis of the PREDIMED-plus study. SCIENTIFIC REPORTS. 2018; 8:Núm artículo 16128
IF: 4,122  
Q: 1

Gomez-Gomez E, Jimenez-Vacas JM, Carrasco-Valiente J, Herrero-Aguayo V, Blanca-Pedregosa AM, Leon-Gonzalez AJ, Valero-Rosa J, Fernandez-Rueda JL, Gonzalez-Serrano T, Lopez-Miranda J, Gahete MD, Castano JP, Requena-Tapia MJ, Luque RM. Plasma ghrelin O-acyltransferase (GOAT) enzyme levels: A novel non-invasive diagnosis tool for patients with significant prostate cancer. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2018; 22(11):5688-5697.
IF: 4,302  
Q: 1

Lopez-Bascon MA, Calderon-Santiago M, Sanchez-Ceinos J, Fernandez-Vega A, Guzman-Ruiz R, Lopez-Miranda J, Malagon MM, Priego-Capote F. Influence of sample preparation on lipidomics analysis of polar lipids in adipose tissue. TALANTA. 2018; 177:86-93.
IF: 4,244  
Q: 1

Ramos-Molina B, Castellano-Castillo D, Alcaide-Torres J, Pastor O, Diaz RD, Salas-Salvado J, Lopez-Moreno J, Fernandez-Garcia JC, Macias-Gonzalez M, Cardona F, Tinahones FJ. Differential effects of restrictive and malabsorptive bariatric surgery procedures on the serum lipidome in obese subjects. JOURNAL OF CLINICAL LIPIDOLOGY. 2018; 12(6):1502-1512.
IF: 3,58  
Q: 1

Mena-Sanchez G, Babio N, Martinez-Gonzalez MA, Corella D, Schroder H, Vioque J, Romaguera D, Martinez JA, Lopez-Miranda J, Estruch R, Warnberg J, Bueno-Cavanillas A, Serra-Majem L, Tur JA, Aros F, Tinahones FJ, Sanchez VM, Lapetra J, Pinto X, Vidal J, Vazquez C, Ordovas JM, Delgado-Rodriguez M, Matia-Martin R, Basora J, Buil-Cosiales R, Fernandez-Carrion R, Fito M, Salas-Salvado J. Fermented dairy products, diet quality, and cardio-metabolic profile of a Mediterranean cohort at high cardiovascular risk. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES. 2018; 28(10):1002-1011.
IF: 3,318  
Q: 1

Morales-Rull JL, Bielsa S, Conde-Martel A, Aramburu-Bodas O, Llacer P, Quesada MA, Suarez-Pedreira I, Manzano L, Barquero MMP, Porcel JM. Pleural effusions in acute decompensated heart failure: Prevalence and prognostic implications. EUROPEAN JOURNAL OF INTERNAL MEDICINE. 2018; 52:49-53.
IF: 3,282  
Q: 1

Galilea-Zabalza I, Buil-Cosiales P, Salas-Salvado J, Toledo E, Ortega-Azorin C, Diez-Espino J, Vazquez-Ruiz Z, Zomeno MD, Vioque J, Martinez JA, Romaguera D, Perez-Farinos N, Lopez-Miranda J, Estruch R, Bueno-Cavanillas A, Aros F, Tur JA, Tinahones F, Serra-Majem L, Marcos-Delgado A, Ortega-Calvo M, Vazquez C, Pinto X, Vidal J, Daimiel L, Delgado-Rodriguez M, Matia P, Corella D, Diaz-Lopez A, Babio N, Munoz MA, Fito M, Gonzalez-Palacios S, Abete I, Garcia-Rios A, Ros E, Martinez-Gonzalez MA. Mediterranean diet and quality of life: Baseline cross-sectional analysis of the PREDIMED-PLUS trial. PLOS ONE. 2018; 13(6):Núm artículo e0198974
IF: 2,766  
Q: 1

Grosjean F, Yubero-Serrano EM, Zheng F, Esposito V, Swamy S, Elliot SJ, Cai WJ, Vlassara H, Salem F, Striker GE. Pharmacologic control of oxidative stress and inflammation determines whether diabetic glomerulosclerosis progresses or decreases: A pilot study in sclerosis-prone mice. PLOS ONE. 2018; 13(9): Núm artículo e0204366
IF: 2,766  
Q: 1

Jimenez-Jimenez C, Lara-Chica M, Palomares B, Collado JA, Lopez-Miranda J, Munoz E, Calzado MA. Effect of N-acyl-dopamines on beta cell differentiation and wound healing in diabetic mice. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH. 2018; 1865(11):1539-1551.
IF: 4,651  
Q: 1

de Isla LP, Alonso R, Muniz-Grijalvo O, Diaz-Diaz JL, Zambon D, Miramontes JP, Fuentes F, de Diego JJG, Gonzalez-Estrada A, Mata N, Saltijeral A, Barreiro M, Tomas M, de Andres R, Argues R, Gotarredona MPS, Herrero SN, Palazon RJP, de Caralt TM, de Centi LAS, Zhilina S, Perez SE, Padro T, Mata P. Coronary computed tomographic angiography findings and their therapeutic implications in asymptomatic patients with familial hypercholesterolemia. Lessons from the SAFEHEART study. JOURNAL OF CLINICAL LIPIDOLOGY. 2018; 12(4):948-957.
IF: 3,58  
Q: 1

Bikdeli B, Sharif-Kashani B, Bikdeli B, Valle R, Falga C, Riera-Mestre A, Mazzolai L, Verhamme P, Wells PS, Torrero JFSM, Lopez-Jimenez L, Monreal M. Impact of Thrombus Sidedness on Presentation and Outcomes of Patients with Proximal Lower Extremity Deep Vein Thrombosis. SEMINARS IN THROMBOSIS AND HEMOSTASIS. 2018; 44(4):341-347.
IF: 3,345  
Q: 2

Sanchez-Hidalgo JM, Duran-Martinez M, Molero-Payan R, Rufian-Pena S, Arjona-Sanchez A, Casado-Adam A, Cosano-Alvarez A, Briceno-Delgado J. Gastrointestinal stromal tumors: a multidisciplinary challenge. WORLD JOURNAL OF GASTROENTEROLOGY. 2018; 24(18):1925-1941.
IF: 3,3  
Q: 2

Romero-Saldana M, Tauler P, Vaquero-Abellan M, Lopez-Gonzalez AA, Fuentes-Jimenez FJ, Aguilo A, Alvarez-Fernandez C, Molina-Recio G, Bennasar-Veny M. Validation of a non-invasive method for the early detection of metabolic syndrome: a diagnostic accuracy test in a working population. BMJ OPEN. 2018; 8(10):Núm artículo e020476
IF: 2,413  
Q: 2

Moustafa F, Stehouwer A, Kamphuisen P, Sahuquillo JC, Samperiz A, Alfonso M, Pace F, Surinach JM, Blanco-Molina A, Mismetti P, Monreal M. Management and outcome of major bleeding in patients receiving vitamin K antagonists for venous thromboembolism. THROMBOSIS RESEARCH. 2018; 171:74-80.
IF: 2,779  
Q: 2

Katsiki N, Kolovou G, Perez-Martinez P, Mikhailidis DP. Dyslipidaemia in the elderly: to treat or not to treat?. EXPERT REVIEW OF CLINICAL PHARMACOLOGY. 2018; 11(3):259-278.
IF: 2,758  
Q: 2

Fernandez CS, Castilla-Guerra L, Hinojosa JC, Surinach JM, de Bilbao FA, Tamarit JJ, Diaz JLD, Hernandez JL, Pose A, Montero-Perez-Barquero M, Roquer J, Gallego J, Vivancos J, Mostaza JM. Satisfaction with oral anticoagulants in patients with atrial fibrillation. PATIENT PREFERENCE AND ADHERENCE. 2018; 12:267-274.
IF: 1,733  
Q: 2

Sanchez-Hidalgo JM, Duran-Martinez M, Molero-Payan R, Rufian-Pena S, Arjona-Sanchez A, Casado-Adam A, Cosano-Alvarez A, Briceno-Delgado J. Gastrointestinal stromal tumors: a multidisciplinary challenge. WORLD JOURNAL OF GASTROENTEROLOGY. 2018; 24(18):1925-1941.
IF: 3,3  
Q: 2

Pedro-Botet J, Ascaso JF, Barrios V, De la Sierra A, Escalada J, Millan J, Mostaza JM, Perez-Martinez P, Pinto X, Salas-Salvado J, Valdivielso P. COSMIC project: consensus on the objectives of the metabolic syndrome in clinic. DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY. 2018; 11:683-697.
IF: 2,961  
Q: 3

Katsiki N, Perez-Martinez P, Anagnostis P, Mikhailidis DP, Karagiannis A.Is Nonalcoholic Fatty Liver Disease Indeed the Hepatic Manifestation Metabolic Syndrome?. CURRENT VASCULAR PHARMACOLOGY. 2018; 16(3):219-227.
IF: 2,087  
Q: 3

Lobo JL, Garcia-Fuertes JA, Trujillo-Santos J, Merah A, Blanco-Molina MA, Casado I, Hirmerova J, De Miguel J, Salgado E, Monreal M. Anticoagulant therapy for venous thromboembolism in patients with inflammatory bowel disease. EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY. 2018; 30(5):526-530.
IF: 2,014  
Q: 4

Aller R, Fernandez-Rodriguez C, lo Iacono O, Banares R, Abad J, Carrion JA, Garcia-Monzon C, Caballeria J, Berenguer M, Rodriguez-Peralvarez M, Miranda JL, Vilar-Gomez E, Crespo J, Garcia-Cortes M, Reig M, Navarro JM, Gallego R, Genesca J, Arias-Loste MT, Pareja MJ, Albillos A, Muntane J, Jorquera F, Sola E, Hernandez-Guerra M, Rojo MA, Salmeron J, Caballeria L, Diago M, Molina E, Bataller R, Romero-Gomez M.Consensus document. Management of non-alcoholic fatty liver disease (NAFLD). Clinical practice guideline. GASTROENTEROLOGIA Y HEPATOLOGIA. 2018; 41(5):328-349.
IF:1,078  
Q: 4

Main Publications 2017

de Larriva APA, Norby FL, Chen LY, Soliman EZ, Hoogeveen RC, Arking DE, Loehr LR, Alonso A. Circulating ceruloplasmin, ceruloplasmin-associated genes, and the incidence of atrial fibrillation in the atherosclerosis risk in communities study. INTERNATIONAL JOURNAL OF CARDIOLOGY. 2017.241():223-228.
IF: 6,189
Q: 1    

Casado J, Sanchez M, Garces V, Manzano L, Cerqueiro JM, Epelde F, Garcia-Escriva D, Perez-Silvestre J, Morales JL, Montero-Perez-Barquero M, RICA Investigators Grp. Influence of renal dysfunction phenotype on mortality in decompensated heart failure with preserved and mid-range ejection fraction. INTERNATIONAL JOURNAL OF CARDIOLOGY. 2017.243():332-339.
IF: 6,189
Q: 1 

Sanchez-Gil J, Manzano L, Flather M, Formiga F, Martel AC, Molinero AM, Lopez RQ, Jimenez JLA, Iborra PL, Perez-Calvo JI, Montero-Perez-Barquero M, RICA Investigators. Combining heart rate and systolic blood pressure to improve risk stratification in older patients with heart failure: Findings from the RICA Registry. INTERNATIONAL JOURNAL OF CARDIOLOGY. 2017.230():625-629.
IF: 6,189
Q: 1 

Perez-Martinez P, Mikhailidis DP, Athyros VG, Bullo M, Couture P, Covas MI, de Koning L, Delgado-Lista J, Diaz-Lopez A, Drevon CA, Estruch R, Esposito K, Fito M, Garaulet M, Giugliano D, Garcia-Rios A, Katsiki N, Kolovou G, Lamarche B, Maiorino MI, Mena-Sanchez G, Munoz-Garach A, Nikolic D, Ordovas JM, Perez-Jimenez F, Rizzo M, Salas-Salvado J, Schroder H, Tinahones FJ, de la Torre R, van Ommen B, Wopereis S, Ros E, Lopez-Miranda J. Lifestyle recommendations for the prevention and management of metabolic syndrome: an international panel recommendation. NUTRITION REVIEWS. 2017.75(5):307-326.
IF: 5,291
Q: 1  D: 1

Martinez-Moreno JM, Herencia C, de Oca AM, Diaz-Tocados JM, Vergara N, Gomez-Luna MJ, Lopez-Arguello SD, Camargo A, Peralbo-Santaella E, Rodriguez-Ortiz ME, Canalejo A, Rodriguez M, Munoz-Castaneda JR, Almaden Y. High phosphate induces a pro-inflammatory response by vascular smooth muscle cells and modulation by vitamin D derivatives. CLINICAL SCIENCE. 2017.131(13):1449-1463.
IF: 4,936
Q: 1 

Manzano L, Gonzalez-Franco A, Cerqueiro JM, Perez-Barquero MM. Heart Failure Programs / Units. A Multidisciplinary Approach. REVISTA ESPANOLA DE CARDIOLOGIA. 2017.70(5):410-410.
IF: 4,485
Q: 1 

Camargo A, Rangel-Zuniga OA, Alcala-Diaz J, Gomez-Delgado F, Delgado-Lista J, Garcia-Carpintero S, Marin C, Almaden Y, Yubero-Serrano EM, Lopez-Moreno J, Tinahones FJ, Perez-Martinez P, Roche HM, Lopez-Miranda J. Dietary fat may modulate adipose tissue homeostasis through the processes of autophagy and apoptosis. EUROPEAN JOURNAL OF NUTRITION. 2017.56(4):1621-1628.
IF: 4,37
Q: 1 

Rangel-Zuniga OA, Haro C, Tormos C, Perez-Martinez P, Delgado-Lista J, Marin C, Quintana-Navarro GM, Cerda C, Saez GT, Lopez-Segura F, Lopez-Miranda J, Perez-Jimenez F, Camargo A. Frying oils with high natural or added antioxidants content, which protect against postprandial oxidative stress, also protect against DNA oxidation damage. EUROPEAN JOURNAL OF NUTRITION. 2017.56(4):1597-1607.
IF: 4,37
Q: 1 

Lopez-Moreno J, Quintana-Navarro GM, Camargo A, Jimenez-Lucena R, Delgado-Lista J, Marin C, Tinahones FJ, Striker GE, Roche HM, Perez-Martinez P, Lopez-Miranda J, Yubero-Serrano EM. Dietary fat quantity and quality modifies advanced glycation end products metabolism in patients with metabolic syndrome. MOLECULAR NUTRITION & FOOD RESEARCH. 2017.61(8):-1601029.
IF: 4,323
Q: 1  D: 1

Haro C, Garcia-Carpintero S, Rangel-Zuniga OA, Alcala-Diaz JF, Landa BB, Clemente JC, Perez-Martinez P, Lopez-Miranda J, Perez-Jimenez F, Camargo A. Consumption of Two Healthy Dietary Patterns Restored Microbiota Dysbiosis in Obese Patients with Metabolic Dysfunction. MOLECULAR NUTRITION & FOOD RESEARCH. 2017.61(12):-1700300.
IF: 4,323
Q: 1  D: 1

Blanco-Rojo R, Perez-Martinez P, Lopez-Moreno J, Martinez-Botas J, Delgado-Lista J, Van-Ommen B, Yubero-Serrano E, Camargo A, Ordovas JM, Perez-Jimenez F, Gomez-Coronado D, Lopez-Miranda J. HDL cholesterol efflux normalised to apoA-I is associated with future development of type 2 diabetes: from the CORDIOPREV trial. SCIENTIFIC REPORTS. 2017.7():-12499.
IF: 4,259
Q: 1 

Lopez-Moreno J, Garcia-Carpintero S, Gomez-Delgado F, Jimenez-Lucena R, Vals-Delgado C, Alcala-Diaz JF, Roncero-Ramos I, Rangel-Zuñiga OA, Yubero-Serrano EM, Malagon MM, Ordovas JM, Perez-Martinez P, Lopez-Miranda J, Camargo A. Endotoxemia is modulated by quantity and quality of dietary fat in older adults. Experimental gerontology. 2017. Nov 10. pii: S0531-5565(17)30652-6
IF: 3,34
Q: 1 

Garcia-Rios A, Leon-Acuna A, Lopez-Miranda J, Perez-Martinez P. Lipoprotein (a) Management: Lifestyle and Hormones.C URRENT MEDICINAL CHEMISTRY. 2017.24(10):979-988.
IF: 3,249
Q: 2 

Lopez-Moreno J, Garcia-Carpintero S, Jimenez-Lucena R, Haro C, Rangel-Zuniga OA, Blanco-Rojo R, Yubero-Serrano EM, Tinahones FJ, Delgado-Lista J, Perez-Martinez P, Roche HM, Lopez-Miranda J, Camargo A. Effect of Dietary Lipids on Endotoxemia Influences Postprandial Inflammatory Response. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. 2017.65(35):7756-7763.
IF: 3,154
Q: 1  D:1

Lopez I, Pineda C, Raya AI, Rodriguez-Ortiz ME, Diaz-Tocados JM, Rios R, Rodriguez JM, Aguilera-Tejero E, Almaden Y. Leptin directly stimulates parathyroid hormone secretion. ENDOCRINE.2017. 56(3):675-678.
IF: 3,131
Q: 2 

Rangel-Zuniga OA, Cruz-Teno C, Haro C, Quintana-Navarro GM, Camara-Martos F, Perez-Martinez P, Garcia-Rios A, Garaulet M, Tena-Sempere M, Lopez-Miranda J, Perez-Jimenez F, Camargo A. Differential menopause-versus aging-induced changes in oxidative stress and circadian rhythm gene markers. MECHANISMS OF AGEING AND DEVELOPMENT. 2017.164():41-48.
IF: 3,087
Q: 2

Franco J, Formiga F, Trullas JC, Bautista PS, Conde A, Manzano L, Quiros R, Franco AG, Ezquerro AM, Montero-Perez-Barquero M, RICA Investigators Grp. Impact of prealbumin on mortality and hospital readmission in patients with acute heart failure. EUROPEAN JOURNAL OF INTERNAL MEDICINE. 2017.43():36-41.
IF: 2,96
Q: 1 

Blanco-Molina Á, Trujillo-Santos J, Pesavento R, Rosa V4, Falgá C, Tolosa C, Mazzolai L, Sampériz Á, Duce R, Monreal M, RIETE Investigators. Outcome after discontinuing anticoagulant therapy in women with venous thromboembolism during hormonal use. Thrombosis research. 2017.151 Supl(1):S6-S10.
IF: 2,65
Q: 2 

Garcia-Rios A, Torres-Pena JD, Perez-Jimenez F, Perez-Martinez P. Gut Microbiota: A New Marker of Cardiovascular Disease. CURRENT PHARMACEUTICAL DESIGN. 2017.23(22):3233-3238.
IF: 2,611
Q: 2 

Katsiki N, Perez-Martinez P. Drug therapy for ectopic fat: myth or reality? EXPERT REVIEW OF CARDIOVASCULAR THERAPY. 2017.15(2):71-72.
IF: 0

Other Publications 2017

Giugliano RP, Pedersen TR, Park JG, De Ferrari GM, Gaciong ZA, Ceska R, Toth K, Gouni-Berthold I, Lopez-Miranda J, Schiele F, Mach F, Ott BR, Kanevsky E, Pineda AL, Somaratne R, Wasserman SM, Keech AC, Sever PS, Sabatine MS, FOURIER Investigators. Clinical efficacy and safety of achieving very low LDL-cholesterol concentrations with the PCSK9 inhibitor evolocumab: a prespecified secondary analysis of the FOURIER trial. LANCET. 2017.390(10106):1962-1971.
IF: 47,831
Q: 1  D: 1

de Isla LP, Alonso R, Mata N, Fernandez-Perez C, Muniz O, Diaz-Diaz JL, Saltijeral A, Fuentes-Jimenez F, de Andres R, Zambon D, Piedecausa M, Cepeda JM, Mauri M, Galiana J, Brea A, Munoz-Torrero JFS, Padro T, Argueso R, Miramontes-Gonzalez JP, Badimon L, Santos RD, Watts GF, Mata P. Predicting Cardiovascular Events in Familial Hypercholesterolemia The SAFEHEART Registry (Spanish Familial Hypercholesterolemia Cohort Study). CIRCULATION. 2017.135(22):2133-2144.
IF: 19,309
Q: 1  D:1

Diaz-Tocados JM, Peralta-Ramirez A, Rodriguez-Ortiz ME, Raya AI, Lopez I, Pineda C, Herencia C, de Oca AM, Vergara N, Steppan S, de Mier MVPR, Buendia P, Carmona A, Carracedo J, Alcala-Diaz JF, Frazao J, Martinez-Moreno JM, Canalejo A, Felsenfeld A, Rodriguez M, Aguilera-Tejero E, Almaden Y, Munoz-Castaneda JR. Dietary magnesium supplementation prevents and reverses vascular and soft tissue calcifications in uremic rats. KIDNEY INTERNATIONAL. 2017.92(5):1084-1099.
IF: 8,395
Q: 1

Lazaro P, de Isla LP, Watts GF, Alonso R, Norman R, Muniz O, Fuentes F, Mata N, Lopez-Miranda J, Gonzalez-Juanatey JR, Diaz-Diaz JL, Blasco AJ, Mata P. Cost-effectiveness of a cascade screening program for the early detection of familial hypercholesterolemia. JOURNAL OF CLINICAL LIPIDOLOGY. 2017.11(1):260-271.
IF: 5,812
Q: 1  D: 1

Moreno-Castellanos N, Rodriguez A, Rabanal-Ruiz Y, Fernandez-Vega A, Lopez-Miranda J, Vazquez-Martinez R, Fruhbeck G, Malagon M. The cytoskeletal protein septin 11 is associated with human obesity and is involved in adipocyte lipid storage and metabolism. DIABETOLOGIA. 2017.60(2):324-335.
IF: 6,08
Q: 1 

Munoz-Castaneda JR, Herencia C, de Mier MVPR, Rodriguez-Ortiz ME, Diaz-Tocados JM, Vergara N, Martinez-Moreno JM, Salmeron MD, Richards WG, Felsenfeld A, Kuro-O M, Almaden Y, Rodriguez M. Differential regulation of renal Klotho and FGFR1 in normal and uremic rats. FASEB JOURNAL. 2017.31(9):3858-3867.
IF: 5,498
Q: 1  D: 1

Luque RM, Lopez-Sanchez LM, Villa-Osaba A, Luque IM, Santos-Romero AL, Yubero-Serrano EM, Cara-Garcia M, Alvarez-Benito M, Lopez-Miranda J, Gahete MD, Castano JP. Breast cancer is associated to impaired glucose/insulin homeostasis in premenopausal obese/overweight patients. ONCOTARGET. 2017.8(46):81462-81474.
IF: 5,168
Q: 1 

Oliva-Olivera W, Lhamyani S, Coin-Araguez L, Castellano-Castillo D, Alcaide-Torres J, Yubero-Serrano EM, El Bekay R, Tinahones FJ. Neovascular deterioration, impaired NADPH oxidase and inflammatory cytokine expression in adipose-derived multipotent cells from subjects with metabolic syndrome. METABOLISM-CLINICAL AND EXPERIMENTAL. 2017.71():132-143.
IF: 5,777
Q: 1

Alvarez-Garcia J, Salamanca-Bautista P, Ferrero-Gregori A, Montero-Perez-Barquero M, Puig T, Aramburu-Bodas O, Vazquez R, Formiga F, Delgado J, Arias-Jimenez JL, Vives-Borras M, Gonzalez JMC, Manzano L, Cincaa J. REDINSCOR Grp, RICA Grp. Prognostic Impact of Physician Specialty on the Prognosis of Outpatients With Heart Failure: Propensity Matched Analysis of the REDINSCOR and RICA Registries. REVISTA ESPANOLA DE CARDIOLOGIA. 2017.70(5):347-354.
IF: 4,485
Q: 2

Alvarez-Garcia J, Salamanca-Bautista P, Perez-Barquero MM, Cinca J. About the Specialty Treating Patients With Heart Failure. Response. REVISTA ESPANOLA DE CARDIOLOGIA. 2017.70(7):612-612.
IF: 4,485
Q: 2

Saltijeral A, de Isla LP, Alonso R, Muniz O, Diaz-Diaz JL, Fuentes F, Mata N, de Andres R, Diaz-Soto G, Pastor J, Pinilla JM, Zambon D, Pinto X, Badimon L, Mata P, SAFEHEART Investigators. Attanment of LDL Cholesterol Treatment Goals in Children and Adolescents With Familial Hypercholesterolemia. The SAFEHEART Follow-up Registry. REVISTA ESPANOLA DE CARDIOLOGIA. 2017.70(6):444-450.
IF: 4,485
Q: 2 

Fallaize R, Carvalho-Wells AL, Tierney AC, Marin C, Kiec-Wilk B, Dembinska-Kiec A, Drevon CA, DeFoort C, Lopez-Miranda J, Riserus U, Saris WH, Blaak EE, Roche HM, Lovegrove JA. APOE genotype influences insulin resistance, apolipoprotein CII and CIII according to plasma fatty acid profile in the Metabolic Syndrome. SCIENTIFIC REPORTS. 2017.7():-6274.
IF: 4,259
Q: 1 

Diaz-Tocados JM, Herencia C, Martinez-Moreno JM, de Oca AM, Rodriguez-Ortiz ME, Vergara N, Blanco A, Steppan S, Almaden Y, Rodriguez M, Munoz-Castaneda JR. Magnesium Chloride promotes Osteogenesis through Notch signaling activation and expansion of Mesenchymal Stem Cells. SCIENTIFIC REPORTS.2017.7(1):-7839.
IF: 4,259
Q: 1   

DeFilipp Z, Duarte RF, Snowden JA, Majhail NS, Greenfield DM, Miranda JL, Arat M, Baker KS, Burns LJ, Duncan CN, Gilleece M, Hale GA, Hamadani M, Hamilton BK, Hogan WJ, Hsu JW, Inamoto Y, Kamble RT, Lupo-Stanghellini MT, Malone AK, McCarthy P, Mohty M, Norkin M, Paplham P, Ramanathan M, Richart JM, Salooja N, Schouten HC, Schoemans H, Seber A, Steinberg A, Wirk BM, Wood WA, Battiwalla M, Flowers MED, Savani BN, Shaw BE, CIBMTR Late Effects Quality Life, EBMT Complications Quality Life. Metabolic syndrome and cardiovascular disease following hematopoietic cell transplantation: screening and preventive practice recommendations from CIBMTR and EBMT .BONE MARROW TRANSPLANTATION. 2017.52(2):173-182.
IF: 3,874
Q: 2 

Luciano-Mateo, A. Hernandez-Aguilera, N. Cabre, J. Camps, S. Fernandez-Arroyo, J. Lopez-Miranda, J. A. Menendez and J. Joven. Nutrients in Energy and One-Carbon Metabolism: Learning from Metformin Users. Nutrients. 2017.9(2):E121.
IF: 3,759
Q: 2 

Papandreou C, Bullo M, Tinahones FJ, Martinez-Gonzalez MA, Corella, D, Fragkiadakis GA, Lopez-Miranda J, Estruch R, Fito M, Salas-Salvado J. Serum metabolites in non-alcoholic fatty-liver disease development or reversion, a targeted metabolomic approach within the PREDIMED trial. NUTRITION & METABOLISM. 2017.14():-58.
IF: 2,974
Q: 2 

Oliva-Olivera W, Moreno-Indias I, Coin-Araguez L, Lhamyani S, Torres JA, Fernandez-Veledo S, Vendrell J, Camargo A, El Bekay R, Tinahones FJ. Different response to hypoxia of adipose-derived multipotent cells from obese subjects with and without metabolic syndrome. PLOS ONE. 2017.12(11):-e0188324.
IF: 2,806
Q: 1 

Rosique-Esteban N, Diaz-Lopez A, Martinez-Gonzalez MA, Corella D, Goday A, Martinez JA, Romaguera D, Vioque J, Aros F, Garcia-Rios A, Tinahones F, Estruch R, Fernandez-Garcia JC, Lapetra J, Serra-Majem L, Pinto X, Tur JA, Bueno-Cavanillas A, Vidal J, Delgado-Rodriguez M, Daimiel L, Vazquez C, Rubio MA, Ros E, Salas-Salvado J, PREDIMED-PLUS Investigators. Leisure-time physical activity, sedentary behaviors, sleep, and cardiometabolic risk factors at baseline in the PREDIMED-PLUS intervention trial: A cross-sectional analysis. PLOS ONE. 2017.12(3):-e0172253.
IF: 2,806
Q: 1

Tzoran I, Papadakis E, Brenner B, Valle R, López-Jiménez L, García-Bragado F, Riera-Mestre A, Villalobos A, Quintavalla R, Monreal M, RIETE Investigators. Gender-related differences in the outcome of patients with venous thromboembolism and thrombophilia. Thrombosis research. 2017.151 Supl(1):S11-S15.
IF: 2,65
Q: 2  

Katsiki N, Perez-Martinez P, Mikhailidis DP. Homocysteine and Non-Cardiac Vascular Disease. CURRENT PHARMACEUTICAL DESIGN. 2017.23(22):3224-3232.
IF: 2,611
Q: 2 

Davila LA, Miranda JL, Camargo DA, Zuleta KP, Gonzalez MU, Nava VC, Aguero SD, Villasmil NR. Glycemic index, glycemic load and insulin response of two formulas of isoglucose with different sweeteners and dietary fiber in healthy adults and type-2 diabetes. NUTRICION HOSPITALARIA. 2017.34(3):532-539.
IF: 0,747
Q: 4 

Blasco M, Perez-Martinez P, Lahoz C. Decalogue of the Spanish Society of Arteriosclerosis to reduce therapeutic inertia. Clin Investig Arterioscler. 2017.29():218-223.

Spinola MF, Criado-Garcia J, Perez LL. Internal jugular vein thrombosis, an atypical location of venous thromboembolic disease. MEDICINA CLINICA. 2017.149(10):459-460.
IF: 1,125
Q: 3 

Clinical Research

Active in 2019

A multicenter, open study to assess the safety, tolerability and long-term efficacy of AMG 145 in C-LDL cholesterol in subjects with severe heterozygous familial hypercholestorolemia.
PI: Dr. Francisco Fuentes Jiménez

A randomized, double-blind, parallel-group, active-control trial to assess the efficacy and safety of LCZ696 versus Valsartan on morbidity and mortality in patients with heart failure NYHA Class II-IV).
PI: Dr.  Manuel Montero Pérez-Barquero

Open-label, Single-Arm, Multicenter Study to Evaluate the Safety, Tolerability and Efficacy of Evolocumab for LDL-C Reduction, as Add-on to Diet and Lipid-lowering Therapy, in Pediatric Subjects From 10 to 17 Years of Age With Heterozygous Familial Hypercholesterolemia (HeFH) or Homozygous Familial Hypercholesterolemia (HoFH).
PI: Dr. Francisco Fuentes Jiménez

Estudio aleatorizado, doble ciego, controlado con placebo, de grupos paralelos, multicéntrico, para demostrar los efectos de Sotagliflozina sobre los eventos cardiovasculares y renales en pacientes con diabetes tipo 2, factores de riesgo cardiovascular y función renal moderadamente reducida.
PI: Dr. Francisco Javier Delgado Lista

Estudio aleatorizado, doble ciego, controlado con placebo, de la seguridad y la eficacia de diferentes dosis y pautas posológicas de evinacumab en pacientes con hipercolesterolemia crónica a pesar del tratamiento hipolipidemiante máximo tolerado.
PI: Dr. Pablo Pérez  Martínez

Ensayo clínico de bajo nivel de intervención, abierto y multicéntrico para evaluar el efecto de alirocumab sobre el volumen, la arquitectura y la composición de la placa aterosclerótica en pacientes con Hipercolesterolemia Familiar del Registro.  SAFEHEART. Estudio ARCHITECT.
PI: Dr. Francisco Fuentes Jiménez

Estudio multicéntrico, aleatorizado, doble ciego, de grupos paralelos, con control activo y de 24 semanas de duración para evaluar el efecto de LCZ696 sobre el nivel de NTproBNP, los síntomas, la capacidad de realizar ejercicio y la seguridad en comparación con el tratamiento médico individualizado de las comorbilidades en pacientes con insuficiencia cardíaca y fracción de eyección preservada.
PI: Dr. Francisco Javier Gómez Delgado

Efecto de semaglutida una vez a la semana frente a insulin aspart tres veces al día, ambas añadidas a metformina e insulina glargina optimizada (U100), en sujetos con diabetes tipo 2  Ensayo de 52 semanas, multicéntrico, multinacional, abierto, con control activo, de dos grupos paralelos y aleatorizado en sujetos con diabetes tipo 2.
PI: Dr. Francisco Javier Delgado Lista

Pemafibrato para reducir los episodios cardiovasculares mediante la reducción de los triglicéridos en pacientes con diabetes (PROMINENT).
PI: Dr. Francisco Javier Delgado Lista 

Ensayo de extensión a largo plazo de los ensayos de fase III con hipolipemiantes, para evaluar el efecto del tratamiento a largo plazo con inclisirán administrador en inyecciones subcutáneas a sujetos con alto riesgo cardiovascular y LDL - C elevado. ORIO.
PI: Dr. Francisco Fuentes Jiménez

Efecto sobre la capacidad funcional del tratamiento con hierro intravenoso o hierro oral, comparado con placebo, en pacientes con insuficiencia cardiaca con fracción de eyección del ventrículo izquierdo preservada y anemia ferropénica. ( PREFER-HF).
PI: Dr. Manuel Montero Pérez-Barquero

Estudio multicéntrico, aleatorizado, doble ciego y controlado con placebo para evaluar el impacto de evolocumab sobre los acontecimientos cardiovasculares mayores en pacientes con riesgo cardiovascular elevado sin infarto de miocardio o ictus previo (vesa.
PI: Dr. José López Miranda

Estudio de las cardiopatias con semaglutida en pacientes con diabetes tipo 2 (SOUL).
PI: Dr. Francisco Javier Delgado Lista

 Global anticoagulant registry in the field observing treatment and putcomes in patients with treated acute venous thromboembolic events in the real world GARFIELD.
PI: Dr. Luciano López Jiménez

Estudio observacional multinacional para evaluar la seguridad de Repatha en el embarazo.
PI: Dr.  Francisco Fuentes Jiménez

EU-Wide Cross-Sectional Observational Study of Lipyd-Modifying Therapy Use in Secondary and Primary Care DA VINCI.
PI: Dr. Francisco Javier Gómez Delgado

Long-term legacy effects of LDL-C lowering with alirocumab: observational follow-up of the ODYSSEY OUTCOMES study.
PI: Dr. Francisco Fuentes Jiménez

Manejo del paciente dislipémico pre-diabético en las unidades de lípidos. Estudio PRELIPID.
PI: Dr. José López Miranda

Proyecto MERIDA. Programa de implementación del ejercicio físico en pacientes con insuficiencia cardiaca.
PI: Dr. Manuel Montero Pérez-Barquero

Estudio epidemiológico, multicéntrico y trasversal para caracterizar la prevalencia y distribución de los niveles de lipoproteína (a) en pacientes con enfermedad cardiovascular establecida.
PI: Dr. Francisco Jesús Gómez Delgado

Estudio de prevalencia de amiloidosis en insuficiencia cardiaca.
PI: Dr. Manuel Montero Pérez-Barquero

Members

Dr. José López Miranda

Principal Investigator

Dr. Francisco Pérez Jiménez

Co-Principal Investigator

Dr. Javier Delgado Lista

Co-Principal Investigator

Dr. Pablo Pérez Martínez

Co-Principal Investigator

Dra. Yolanda Almadén Peña

Co-Principal Investigator

yolanda.almaden.exts@juntadeandalucia.es

Team

Antonio Camargo García Antonio García Ríos Elena M. Yubero Serrano Mª Ángeles Blanco Molina Rafael Ángel Fernández de la Puebla Francisco Fuentes Jiménez Luciano López Jiménez Manuel Montero Pérez-Barquero Anabel Pérez Caballero Oriol Rangel-Zuñiga Elena M Yubero-Serrano Juan Francisco Alcalá Díaz Juan Criado García Silvia de la Cruz Ares Francisco Gómez-Delgado Purificación Gómez Luna Francisco Gutiérrez Mariscal Anabel Jiménez Morales Ana León Acuña Irene Roncero Ramos Antonio Pablo Arenas de Larriva Carolina Fernández Gándara Javier López Moreno María Magdalena Pérez Cardelo José David Torres Peña Cristina Vals-Delgado Ana María Vega Rojas Alejandro Villasanta González Rosario Carreras Calero Begoña Díaz Marín José Andrés Morales Martínez Patricia Judith Peña Orihuela Isabel Pérez Corral Gracia Mª Quintana Navarro Ana Redondo Garrido