Publications in 2020
Flores-Giubi ME, Botubol-Ares JM, Duran-Pena MJ, Escobar-Montano F, Zorrilla D, Sanchez-Marquez J, Munoz E, Macias-Sanchez AJ, Hernandez-Galan R. Bond reactivity indices approach analysis of the [2+2] cycloaddition of jatrophane skeleton diterpenoids from Euphorbia gaditana Coss to tetracyclic gaditanone. PHYTOCHEMISTRY. 2020. 180 ():- DOI: 10.1016/j.phytochem.2020.112519
IF: 3,044 Q: 1
Casares L, Garcia V, Garrido-Rodriguez M, Millan E, Collado JA, Garcia-Martin A, Penarando J, Calzado MA, de la Vega L, Munoz E. Cannabidiol induces antioxidant pathways in keratinocytes by targeting BACH1. REDOX BIOLOGY. 2020. 28 ():- DOI: 10.1016/j.redox.2019.101321
IF: 9,986 Q: 1 D: 1
Navarrete C, Garcia-Martin A, DeMesa J, Munoz E. Cannabinoids in Metabolic Syndrome and Cardiac Fibrosis. CURRENT HYPERTENSION REPORTS. 2020. 22 (12):- DOI: 10.1007/s11906-020-01112-7
IF: 3,856 Q: 2
Palomares B, Garrido-Rodriguez M, Gonzalo-Consuegra C, Gomez-Canas M, Saen-oon S, Soliva R, Collado JA, Fernandez-Ruiz J, Morello G, Calzado MA, Appendino G, Munoz E. Delta(9)-Tetrahydrocannabinolic acid alleviates collagen-induced arthritis: Role of PPAR gamma and CB(1)receptors. BRITISH JOURNAL OF PHARMACOLOGY. 2020. 177 (17):4034-4054 DOI: 10.1111/bph.15155
IF: 7,73 Q: 1 D: 1
Navarrete C, Garcia-Martin A, Garrido-Rodriguez M, Mestre L, Feliu A, Guaza C, Calzado MA, Munoz E. Effects of EHP-101 on inflammation and remyelination in murine models of Multiple sclerosis. NEUROBIOLOGY OF DISEASE. 2020. 143 ():- DOI: 10.1016/j.nbd.2020.104994
IF: 5,332 Q: 1
Casares L, Unciti-Broceta JD, Prados ME, Caprioglio D, Mattoteia D, Higgins M, Apendino G, Dinkova-Kostova AT, Munoz E, de la Vega L. Isomeric O-methyl cannabidiolquinones with dual BACH1/NRF2 activity. REDOX BIOLOGY. 2020. 37 ():- DOI: 10.1016/j.redox.2020.101689
IF: 9,986 Q: 1 D: 1
Prieto-Garcia C, Hartmann O, Reissland M, Braun F, Fischer T, Walz S, Schulein-Volk C, Eilers U, Ade CP, Calzado MA, Orian A, Maric HM, Munch C, Rosenfeldt M, Eilers M, Diefenbacher ME. Maintaining protein stability of increment Np63 via USP28 is required by squamous cancer cells. EMBO MOLECULAR MEDICINE. 2020. 12 (4):- DOI: 10.15252/emmm.201911101
IF: 8,821 Q: 1 D: 1
Morrugares R, Correa-Saez A, Moreno R, Garrido-Rodriguez M, Munoz E, de la Vega L, Calzado MA. Phosphorylation-dependent regulation of the NOTCH1 intracellular domain by dual-specificity tyrosine-regulated kinase 2. CELLULAR AND MOLECULAR LIFE SCIENCES. 2020. 77 (13):2621-2639 DOI: 10.1007/s00018-019-03309-9
IF: 6,496 Q: 1
Floris I, Rose T, Rojas JAC, Appel K, Roesch C, Lejeune B. Pro-Inflammatory Cytokines at Ultra-Low Dose Exert Anti-Inflammatory Effect In Vitro: A Possible Mode of Action Involving Sub-Micron Particles?. DOSE-RESPONSE. 2020. 18 (4):- DOI: 10.1177/1559325820961723
IF: 2,438 Q: 2
Mattoteia D, Taglialatela-Scafati O, Munoz E, de la Vega L, Caprioglio D, Appendino G. Regiodivergent Synthesis of ortho- and para-Cannabinoquinones. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. 2020. 2020 (48):7429-7434 DOI: 10.1002/ejoc.202001258
IF: 2,889 Q: 2
Palomares B, Ruiz-Pino F, Garrido-Rodriguez M, Prados ME, Sanchez-Garrido MA, Velasco I, Vazquez MJ, Nadal X, Ferreiro-Vera C, Morrugares R, Appendino G, Calzado MA, Tena-Sempere M, Munoz E. Tetrahydrocannabinolic acid A (THCA-A) reduces adiposity and prevents metabolic disease caused by diet-induced obesity. BIOCHEMICAL PHARMACOLOGY. 2020. 171 ():- DOI: 10.1016/j.bcp.2019.113693
IF: 4,96 Q: 1 D: 1
Caprioglio D, Mattoteia D, Pollastro F, Negri R, Lopatriello A, Chianese G, Minassi A, Collado JA, Munoz E, Taglialatela-Scafati O, Appendino G. The Oxidation of Phytocannabinoids to Cannabinoquinoids. JOURNAL OF NATURAL PRODUCTS. 2020. 83 (5):1711-1715 DOI: 10.1021/acs.jnatprod.9b01284
IF: 3,779 Q: 1
Correa-Saez A, Jimenez-Izquierdo R, Garrido-Rodriguez M, Morrugares R, Munoz E, Calzado MA. Updating dual-specificity tyrosine-phosphorylation-regulated kinase 2 (DYRK2): molecular basis, functions and role in diseases. CELLULAR AND MOLECULAR LIFE SCIENCES. 2020. 77 (23):4747-4763 DOI: 10.1007/s00018-020-03556-1
IF: 6,496 Q: 1
Publications in 2019
Morrugares R, Correa-Sáez A, Moreno R, Garrido-Rodríguez M, Muñoz E, de la Vega L, Calzado MA. Phosphorylation-dependent regulation of the NOTCH1 intracellular domain by dual-specificity tyrosine-regulated kinase 2. Cell Mol Life Sci. 2019 Oct 11. doi: 10.1007/s00018-019-03309-9
IF: 7,014 D: 1
García-Martín A, Garrido-Rodríguez M, Navarrete C, Caprioglio D, Palomares B, DeMesa J, Rolland A, Appendino G, Muñoz E. Cannabinoid derivatives acting as dual PPARγ/CB2 agonists as therapeutic agents for systemic sclerosis. Biochem Pharmacol. 2019 May; 163:321-334. doi: 10.1016/j.bcp.2019.02.029.
IF: 4,825 D: 1
Ruiz EJ, Diefenbacher ME, Nelson JK, Sancho R, Pucci F, Chakraborty A, Moreno P, Annibaldi A, Liccardi G, Encheva V, Mitter R, Rosenfeldt M, Snijders AP, Meier P, Calzado MA, Behrens A. LUBAC determines chemotherapy resistance in squamous cell lung cancer. J Exp Med. 2019 Feb 4;216(2):450-465. doi: 10.1084/jem.20180742
IF: 10,892 D: 1
Garrido-Rodríguez M, Ortea I, Calzado MA, Muñoz E, García V. SWATH proteomic profiling of prostate cancer cells identifies NUSAP1 as a potential molecular target for Galiellalactone. J Proteomics. 2019 Feb 20; 193:217-229. doi: 10.1016/j.jprot.2018.10.012.
IF: 3, 537 Q: 1
Aguareles J, Paraíso-Luna J, Palomares B, Bajo-Grañeras R, Navarrete C, Ruiz-Calvo A, García-Rincón D, García-Taboada E, Guzmán M, Muñoz E, Galve-Roperh I. Oral administration of the cannabigerol derivative VCE-003.2 promotes subventricular zone neurogenesis and protects against mutant huntingtin-inducedneurodegeneration. Transl Neurodegener. 2019 Mar 8;8:9. doi:10.1186/s40035-019-0148-x
IF: 5,534 Q: 1
Publications in 2018
Ruiz EJ, Diefenbacher ME, Nelson JK, Sancho R, Pucci F, Chakraborty A, Moreno P, Annibaldi A, Liccardi G, Encheva V, Mitter R, Rosenfeldt M, Snijders AP, Meier P, Calzado MA, Behrens A. LUBAC determines chemotherapy resistance in squamous cell lung cancer. J Exp Med. 2019 Feb 4;216(2):450-465.
IF: 10.892 Q: 1 D: 1
Minassi A, Rogati F, Cruz C, Prados ME, Galera N, Jinenez C, Appendino G, Bellido ML, Calzado MA, Caprioglio D, Munoz E. Triterpenoid Hydroxamates as HIF Prolyl Hydrolase Inhibitors. JOURNAL OF NATURAL PRODUCTS. 2018; 81(10):2235-2243.
IF: 3,885 Q: 1 D: 1
Moreno P, Jimenez-Jimenez C, Garrido-Rodriguez M, Calderon-Santiago M, Molina S, Lara-Chica M, Priego-Capote F, Salvatierra A, Munoz E, Calzado MA. Metabolomic profiling of human lung tumor tissues - nucleotide metabolism as a candidate for therapeutic interventions and biomarkers. MOLECULAR ONCOLOGY. 2018; 12(10):1778-1796.
IF: 5,264 Q: 1
del Rio C, Cantarero I, Palomares B, Gomez-Canas M, Fernandez-Ruiz J, Pavicic C, Garcia-Martin A, Bellido ML, Ortega-Castro R, Perez-Sanchez C, Lopez-Pedrera C, Appendino G, Calzado MA, Munoz E. VCE-004.3, a cannabidiol aminoquinone derivative, prevents bleomycin-induced skin fibrosis and inflammation through PPAR gamma- and CB2 receptor-dependent pathways. BRITISH JOURNAL OF PHARMACOLOGY. 2018. 175(19):3813-3831.
IF: 6,81 Q: 1 D: 1
Navarrete C, Carrillo-Salinas F, Palomares B, Mecha M, Jimenez-Jimenez C, Mestre L, Feliu A, Bellido ML, Fiebich BL, Appendino G, Calzado MA, Guaza C, Munoz E. Hypoxia mimetic activity of VCE-004.8, a cannabidiol quinone derivative: implications for multiple sclerosis therapy. JOURNAL OF NEUROINFLAMMATION. 2018; 15:Núm artículo 64
IF: 5,193 Q: 1
Jimenez-Jimenez C, Lara-Chica M, Palomares B, Collado JA, Lopez-Miranda J, Munoz E, Calzado MA. Effect of N-acyl-dopamines on beta cell differentiation and wound healing in diabetic mice. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH. 2018; 1865(11):1539-1551.
IF: 4,651 Q: 1
Garcia-Martin A, Garrido-Rodriguez M, Navarrete C, del Rio C, Bellido ML, Appendino G, Calzado MA, Munoz E. EHP-101, an oral formulation of the cannabidiol aminoquinone VCE-004.8, alleviates bleomycin-induced skin and lung fibrosis. BIOCHEMICAL PHARMACOLOGY. 2018; 157:304-313.
IF: 4,235 Q: 1
del Rio C, Millan E, Garcia V, Appendino G, DeMesa J, Munoz E. The endocannabinoid system of the skin. A potential approach for the treatment of skin disorders. BIOCHEMICAL PHARMACOLOGY. 2018; 157:122-133.
IF: 4,235 Q: 1
Palomares B, Ruiz-Pino F, Navarrete C, Velasco I, Sanchez-Garrido MA, Jimenez-Jimenez C, Pavicic C, Vazquez MJ, Appendino G, Bellido ML, Calzado MA, Tena-Sempere M, Munoz E. VCE-004.8, A Multitarget Cannabinoquinone, Attenuates Adipogenesis and Prevents Diet-Induced Obesity. SCIENTIFIC REPORTS. 2018; 8:Núm artículo 16092
IF: 4,122 Q: 1
Garcia C, Gomez-Canas M, Burgaz S, Palomares B, Gomez-Galvez Y, Palomo-Garo C, Campo S, Ferrer-Hernandez J, Pavicic C, Navarrete C, Bellido ML, Garcia-Arencibia M, Pazos MR, Munoz E, Fernandez-Ruiz J. Benefits of VCE-003.2, a cannabigerol quinone derivative, against inflammation-driven neuronal deterioration in experimental Parkinson's disease: possible involvement of different binding sites at the PPAR gamma receptor. JOURNAL OF NEUROINFLAMMATION. 2018; 15:Núm artículo 19
IF: 5,193 Q: 1
Nizet S, Munoz E, Fiebich BL, Abuja PM, Kashofer K, Zatloukal K, Tangermann S, Kenner L, Tschegg C, Nagl D, Scheichl L, Meisslitzer-Ruppitsch C, Freissmuth M, Berger T. Clinoptilolite in Dextran Sulphate Sodium-Induced Murine Colitis: Efficacy and Safety of a Microparticulate Preparation. INFLAMMATORY BOWEL DISEASES. 2018; 24(1):54-66.
IF: 4,347 Q: 1
Rodriguez-Cueto C, Santos-Garcia I, Garcia-Toscano L, Espejo-Porras F, Bellido M, Fernandez-Ruiz J, Munoz E, de Lago E. Neuroprotective effects of the cannabigerol quinone derivative VCE-003.2 in SOD1(G93A) transgenic mice, an experimental model of amyotrophic lateral sclerosis. BIOCHEMICAL PHARMACOLOGY. 2018; 157:217-226.
IF: 4,235 Q: 1
Luesma MJ, Cantarero I, Castiella T, Sanchez-Cano AI, Iruzubieta P, Junquera C. Ultrastructural and immunohistochemical study of phenotypic switch in gastrointestinal smooth muscle cells. MICROSCOPY RESEARCH AND TECHNIQUE. 2018; 81(11):1233-1240.
IF: 1,087 Q: 3
Pollastro F, Caprioglio D, Del Prete D, Rogati F, Minassi A, Taglialatela-Scafati O, Munoz E, Appendino G. Cannabichromene. NATURAL PRODUCT COMMUNICATIONS. 2018; 3(9):1189-1194.
IF: 8,9 Q: 4
Appel K, Munoz E, Navarrete C, Cruz-Teno C, Biller A, Thiemann E. Immunomodulatory and Inhibitory Effect of Immulina (R), and Immunloges (R) in the Ig-E Mediated Activation of RBL-2H3 Cells. A New Role in Allergic Inflammatory Responses. PLANTS-BASEL. 2018; 7(1):Núm artículo 13
Publications in 2017
Nadal X, del Rio C, Casano S, Palomares B, Ferreiro-Vera C, Navarrete C, Sanchez-Carnerero C, Cantarero I, Bellido ML, Meyer S, Morello G, Appendino G, Munoz E. Tetrahydrocannabinolic acid is a potent PPAR gamma agonist with neuroprotective activity. BRITISH JOURNAL OF PHARMACOLOGY. 2017.174(23):4263-4276.
IF: 5,491 Q: 1 D: 1
Saliba SW, Marcotegui AR, Fortwangler E, Ditrich J, Perazzo JC, Munoz E, de Oliveira ACP, Fiebich BL. AM404, paracetamol metabolite, prevents prostaglandin synthesis in activated microglia by inhibiting COX activity. JOURNAL OF NEUROINFLAMMATION. 2017. 14(1):246.
IF: 5,102 Q: 1
Nizet S, Muñoz E, Fiebich BL, Abuja PM, Kashofer K, Zatloukal K, Tangermann S, Kenner L, Tschegg C, Nagl D, Scheichl L, Meisslitzer-Ruppitsch C, Freissmuth M, Berger T. Clinoptilolite in Dextran Sulphate Sodium-Induced Murine Colitis: Efficacy and Safety of a Microparticulate Preparation. INFLAMMATORY BOWEL DISEASES. 2017. 24(1):54-66.
IF: 4,525 Q: 1
Gomez-Canas M, Morales P, Garcia-Toscano L, Navarrete C, Munoz E, Jagerovic N, Fernandez-Ruiz J, Garcia-Arencibia M, Pazos MR. Corrigendum to "Biological characterization of PM226, a chromenoisoxazole, as a selective CB2 receptor agonist with neuroprotective profile" [Pharmacol. Res. 110 (August 2016) (2016) 205-215]. PHARMACOLOGICAL RESEARCH. 2017.120:302.
IF: 4,48 Q: 1
Del Prete D, Taglialatela-Scafati O, Minassi A, Sirignano C, Cruz C, Bellido ML, Munoz E, Appendino G. Electrophilic Triterpenoid Enones: A Comparative Thiol-Trapping and Bioactivity Study. JOURNAL OF NATURAL PRODUCTS. 2017.80(8):2276-2283.
IF: 3,281 Q: 1
Egas V, Millan E, Collado JA, Ramirez-Apan T, Mendez-Cuesta CA, Munoz E, Delgado G. Effect of natural and semi-synthetic cadinanes from Heterotheca inuloides on NF-kappa B, Nrf2 and STAT3 signaling pathways and evaluation of their in vitro cytotoxicity in human cancer cell lines. BIOORGANIC & MEDICINAL CHEMISTRY. 2017.25(12):3135-3147.
IF: 2,93 Q: 2
Olmedo DA, Lopez-Perez JL, del Olmo E, Bedoya LM, Sancho R, Alcami J, Munoz E, San Feliciano A, Gupta MP. Neoflavonoids as Inhibitors of HIV-1 Replication by Targeting the Tat and NF-B Pathways. MOLECULES. 2017.22(2):-E321.
IF: 2,861 Q: 2
Formisano C, Sanna C, Ballero M, Chianese G, Sirignano C, Rigano D, Millan E, Munoz E, Taglialatela-Scafati O. Anti-inflammatory sesquiterpene lactones from Onopordum illyricum L. (Asteraceae), an Italian medicinal plant. FITOTERAPIA. 2017.116:61-65.
IF: 2,698 Q: 2
