Research groups

GC15 Invasive cardiology and cell therapy

Our group has 16 cardiologists, of which 8 are dedicated to interventional cardiology in both adults and children (Congenital Heart Disease, Electrophysiology, Valvular Diseases and Coronary Diseases), 5 dedicated to the study of advanced and specialized heart failures, including cardiac/heart transplants, and 3 dedicated to imaging techniques and functional tests (Ecocardigraphs, Stress Tests, Holter, etc.).

The main research of our group focuses on interventional cardiology and cell therapy. The strategy and objectives of our research include:

  • Determination of the role of stem cells in ischemic and non-ischemic cardiac pathologies.
  • Development and deepening of our knowledge on percutaneous treatment of complex coronary lesions.
  • Study of transluminal disease of congenital heart disease in childhood and adulthood.
  • Development and deepening of our knowledge on percutaneous implantation of valvular prostheses.

Our group is nationally renowned in the treatment of different cardiovascular pathologies, especially in the field of Congenital Heart Disease, Structural Heart Disease, Coronary Disease and Cell Therapy, demonstrated not only by the excellent clinical results but also by the high number of scientific publications.

Our group works in close collaboration with the Cell Therapy Unit of the Reina Sofia University Hospital to develop clinical studies including the use of stem cells and related with myocardial regeneration. The majority of the group members carry out a wide range of research activities and contribute to broadening the knowledge in the area by publishing in high impact journals in the field of clinical research.

Research Lines

Transluminal treatment is the most commonly chosen treatment option for most patients suffering from coronary diseases. However, there are coronary lesions that are difficult to treat: bifurcations and chronic occlusions. Our group develops a long-term clinical research on percutaneous treatment for these complex coronary lesions.

The structural and valvular cardiac pathologies have been typically treated surgically. Our group has been a pioneer in developing a technology that allows transcatheter treatment, but many open questions about the impact and evolution of the treatment in patients still remain. The group has various ongoing projects focused on the study of this type of treatments.

The clinical guidelines related with this type of treatments change from year to year. The knowledge about the possible complications, and above all, longitunal follow up of patients, is decisive when setting up the guidelines for clinical practice. Our group has implanted aorta and pulmonary prostheses percutaneously from an early outset, allowing us now to analyze the long-term results, in comparison with other clinical research groups who have incorporated the technique to their practice much later.

The percutaneous treatment of the mitral valve is technically very challenging. The extensive experience of our group in structural heart diseases has made us a reference at national level when it comes to transluminal treatment of heart diseases. In this area, we have collected a wide database that can be used for clinical research, including joint research ventures with other health care and research entities.

Our group has been accredited as a reference center for the treatment of Congenital Heart Disease in both children and adults, offering us a privileged and unique position on national level, and gives us the advantage to tackle better this type of disease. We offer the widest set of treatments of Aortic Coarctation and Subaortic Membrane Stenosis on international level, and have published a number of articles on this matter in first decile journals.

The Cell Therapy Unit of our hospital carries out numerous research projects in collaboration with the different clinical areas of the hospital. We started cell therapy treatments initially in patients with cardiac pathologies. Currently, 3 clinical trials are underway in patients with Myocardial Infarction, Chronic Occlusions and in Dilated Cardiomyopathy.

We have published the results of various studies of heart failures and continue various lines of research in this area. As a consequence, we have recently obtained accreditation for our advanced heart failure treatment.

Imaging techniques, such as the Transesophageal Ultrasound are often required for the monitoring of percutaneous treatment of Structural Cardiopathy.  The identification of suitable patients, the increased success rate and the short and long term follow-up of the patients constitutes one our most long-term and highly productive research lines.

Networks

    Dr Manuel Pan Álvarez-Ossorio is member of the work group "European Bifurcation Club" and leader of the organization of many of the meetings and courses organized by the group on an international level

    Dr Miguel A Romero Moreno is member of the Working Group on Grown Up Congenital Heart Disease of the European Society of Cardiology

    Dr. Anguita is the president of the Spanish Society of Cardiology (Sociedad Española de Cardiología)

    Dr Anguita and Dr Pan are both active members of the group that develops the guidelines for clinical practice of the Spanish Society of Cardiology (Sociedad Española de Cardiología).

Keywords

  • Cardiac interventions
  • cellular therapy
  • stents
  • percutaneous aortic valves
  • closing birth defects

Additional Information

Highlighted publications with more than 100 citations

  • Medina A, Suárez de Lezo J, Pan M.  [A new classification of coronary bifurcation lesions]. Rev Esp Cardiol. 2006 Feb;59(2):183. Spanish. No abstract available.
  • Pan M, de Lezo JS, Medina A, Romero M, Segura J, Pavlovic D, Delgado A, Ojeda S, Melián F, Herrador J, Ureña I, Burgos L. Rapamycin-eluting stents for the treatment of bifurcated coronary lesions: a randomized comparison of a simple versus complex strategy. Am Heart J. 2004 Nov;148(5):857-64.
  • Louvard Y, Thomas M, Dzavik V, Hildick-Smith D, Galassi AR, Pan M, Burzotta F, Zelizko M, Dudek D, Ludman P, Sheiban I, Darremont O, Kastrati A, Ludwig J, Iakovou I, Brunel P, Lansky A, Meerkin D, Legrand V, Medina A, Lefèvre T. Classification of coronary artery bifurcation lesions and treatments: time for a consensus!. Catheter Cardiovasc Interv. 2008 Feb 1;71(2):175-83. DOI: 10.1002/ccd.21314.
  • Suárez de Lezo J, Pan M, Romero M, Medina A, Segura J, Pavlovic D, Martinez C, Tejero I, Perez Navero J, Torres F, et al. Balloon-expandable stent repair of severe coarctation of aorta. Am Heart J. 1995 May;129(5):1002-8.
  • Suárez de Lezo J, Pan M, Romero M, Medina A, Segura J, Lafuente M, Pavlovic D, Hernández E, Melián F, Espada J. Immediate and follow-up findings after stent treatment for severe coarctation of aorta. Am J Cardiol. 1999 Feb 1;83(3):400-6.

Ongoing International projects

  • Atlantis
  • Reshape-HF
  • Secure. Secondary Prevention of Cardiovascular Disease in the Elderly
    The Secure project has received the award for the best European cooperative R&D project.

The group has received a total of 55 awards for its publications in high impact journals of in the field.

GC15 Invasive cardiology and cell therapy

Principal Investigator
Manuel Pan Álvarez-Ossorio

Researchers
Manuel Pablo Anguita Sanchez
José Mª Arizón del Prado
Juan Carlos Castillo Domínguez
Mónica Mª Delgado Ortega
Amador López Granados
Francisco Mazuelos Bellido
Mª Dolores Mesa Rubio
Soledad Ojeda Pineda
Djordje Pavlovic
Miguel Ángel Romero Moreno
Martín Ruíz Ortíz
José Mª Segura Saint-Gerons
Javier Suárez de Lezo Herreros de Tejada

Post-Doctoral Researcher
José López Aguilera

Clinical Resesarcher
Aurora Luque Moreno

Pre-Doctoral Researcher
Francisco José Hidalgo Lesmes

Administrative Staff
Eva Cebrián Salgado

Projects

Active projects

National

Pan Alvarez-Ossorio, M. Valoración mediante ratio de presión instantánea del compromiso funcional del ramo lateral tras la implantación de stent en el vaso principal en lesiones coronarias en bifurcación. Funding agency: National Institute of Health Carlos III (ISCIII). Reference: PI18/00750

International

Romero Moreno, MA. SECURE - Comparing the effectiveness of existing healthcare interventions in the elderly; Funding Agency: European Commission; Reference: PHC17-2014-002

Finished projects

Pan Álvarez-Ossorio, M. Use of the jailed guidewire technique in the percutaneous treatment of coronary bifurcation stenting: A randomized study of stereoscopic microcospy. Funding agency: National Institute of Health Carlos III (ISCIII). Reference: PI12/00440

Publications

Publications 2019

Anguita P, Anguita M, Castillo JC, Gamez P, Bonilla V, Herrera M; Are Dentists in Our Environment Correctly Following the Recommended Guidelines for Prophylaxis of Infective Endocarditis?. REVISTA ESPANOLA DE CARDIOLOGIA. 2019 Jan;72(1):86-88. doi: 10.1016/j.rec.2018.04.029.
IF: 5,126
Q: 1

Hidalgo F, Pan M, Ojeda S, de Lezo JS, Lostalo A, Luque A, Martin E, Segura J, Mazuelos F, Romero M; Feasibility and Efficacy of the Jailed Pressure Wire Technique for Coronary Bifurcation Lesions. JACC-CARDIOVASCULAR INTERVENTIONS. 2019 Jan 14;12(1):109-111. doi: 10.1016/j.jcin.2018.10.036. 
IF: 9,544
D: 1

Anguita P, Castillo JC, Herrera M, Anguita M; Prophylaxis of Infective Endocarditis in Dentistry: Analysis of the Situation After Almost a Decade of Clinical Practice Guidelines. Response. REVISTA ESPANOLA DE CARDIOLOGIA (Engl Ed). 2019 Jan;72(1):96. doi: 10.1016/j.rec.2018.07.018.
IF: 5,126
Q: 1 

del Pino MDL, Ortiz MR, Ortega MD, Fernandez JS, Quero CF, Jimenez ED, Moreno MR, Saint-Gerons JS, Pineda SO, Pan Alvarez-Ossorio M, Rubio DM; Prosthesis-patient mismatch after transcatheter aortic valve replacement: prevalence and medium term prognostic impact. INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING. 2019 May;35(5):827-836. doi: 10.1007/s10554-018-01519-z.
IF: 1,86
Q: 3 

Sanchez MA, Martin JJA, Fillat AC, Doblas JJG, Rivera LP, Goya IL, Rodrigo FR, Romo AI, Miguel CM, Masip AE, Melchor LS, Bueno H, Molina BD, Ferreira-Gonzalez I, Somoza FJE. Cardiologists and the Cardiology of the Future. Vision and proposals of the Spanish Society of Cardiology for the Cardiology of the 21st Century. REVISTA ESPANOLA DE CARDIOLOGIA (Engl Ed). 2019 Aug;72(8):649-657. doi: 10.1016/j.rec.2019.02.025. 
IF: 5,126
Q: 1    

Rius JB, Huelmos A, Sanchez MA. Health Care Simulation in Cardiology: Promises and Realities. REVISTA ESPANOLA DE CARDIOLOGIA (Engl Ed). 2019 Aug;72(8):606-607. doi: 10.1016/j.rec.2019.02.018. 
IF: 5,126
Q: 1    

Fernandez JJS, Ortiz MR, Luque CO, Galvez JMC, Penas ER, Rubio DM, Ortega MD, Dominguez JCC, Sanchez MA, Aguilera JL, Avalos FC, Alvarez-Ossorio MP. Long-term Survival in a Spanish Population With Stable Ischemic Heart Disease. The CICCOR Registry. REVISTA ESPANOLA DE CARDIOLOGIA (Engl Ed). 2019 Oct;72(10):827-834. doi: 10.1016/j.rec.2018.08.019. 
IF: 5,126
Q: 1    

Ruiz-Ortiz M, Rodriguez-Diego S, Delgado M, Kim J, Weinsaft JW, Ortega R, Carnero L, Sanchez JJ, Carrasco F, Lopez-Aguilera J, Lopez-Granados A, Arizon JM, Paredes N, Oneto-Fernandez J, Pan M, Mesa D. Myocardial deformation and acute cellular rejection after heart transplantation: Impact of inter-vendor variability in diagnostic effectiveness. ECHOCARDIOGRAPHY. 2019 Dec;36(12):2185-2194. doi: 10.1111/echo.14544. 
IF: 1,287

Cequier A, de Prado AP, Moreno R, Cosin-Sales J, de Sa EL, Evangelista A, Bueno H, Anguita M. Percutaneous cardiological intervention and cardiac surgery: patient-centered care. Position statement of the Spanish Society of Cardiology. REVISTA ESPANOLA DE CARDIOLOGIA (Engl Ed). 2019 Aug;72(8):658-663. doi: 10.1016/j.rec.2019.02.024.
IF: 5,126
Q: 1    

Romero M, Suarez-de-Lezo J, Herrera C, Pan M, Lopez-Aguilera J, Suarez-de-Lezo J, Baeza-Garzon F, Hidalgo-Lesmes FJ, Fernandez-Lopez O, Martinez-Atienza J, Cebrian E, Martin-Palanco V, Jimenez-Moreno R, Gutierrez-Fernandez R, Nogueras S, Carmona MD, Ojeda S, Cuende N, Mata R; Randomised, double-blind, placebo-controlled clinical trial for evaluating the efficacy of intracoronary injection of autologous bone marrow mononuclear cells in the improvement of the ventricular function in patients with idiopathic dilated myocardiopathy: a study protocol. BMC CARDIOVASCULAR DISORDERS. 2019 Aug 22;19(1):203. doi: 10.1186/s12872-019-1182-4.
IF: 1,947
Q: 3 

Fernandez EC, Granados AL, Martinez MDZ, del Castillo-Medina R; Consensus in cardiology on non-vitamin-K oral anticoagulants for patients with atrial fibrillation. CURRENT MEDICAL RESEARCH AND OPINION. 2019 Sep;35(9):1571-1582. doi: 10.1080/03007995.2019.1605049.
IF: 2,665
Q: 1

Plaza-Martin M, Sanmartin-Fernandez M, Alvarez-Alvarez B, Andrea R, Seoane-Garcia T, Gonzalez-D'Gregorio J, Hernandez-Betancor I, Rozado J, Carrasco-Avalos F, Alameda-Ortiz MD, Gomez-Talavera S, Sanchis J, Sanchez MA, Peral-Disdier V, Ibanez B, Diaz SD, G; Contemporary differences between men and women with acute coronary syndromes: CIAM multicenter registry. JOURNAL OF CARDIOVASCULAR MEDICINE. 2019 Aug;20(8):525-530. doi: 10.2459/JCM.0000000000000812.
IF: 1,427
Q: 4

Poletti E, Azzalini L, Ayoub M, Ojeda S, Zivelonghi C, La Manna A, Bellini B, Lostalo A, Luque A, Venuti G, Montorfano M, Agostoni P, Pan M, Carlino M, Mashayekhi K; Conventional vascular access site approach versus fully trans-wrist approach for chronic total occlusion percutaneous coronary intervention: a multicenter registry. CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS. 2019 Oct 9. doi: 10.1002/ccd.28513.
IF: 2,551
Q: 2 
Gonzalez-Vilchez F, Delgado JF, Palomo J, Mirabet S, Diaz-Molina B, Almenar L, Arizon JM, Rangel-Sousa D, Perez-Villa F, Garrido IP, de la Fuente L, Gomez-Bueno M, Sanz ML, Crespo-Leiro MG; Conversion From Immediate-Release Tacrolimus to Prolonged-Release Tacrolimus in Stable Heart Transplant Patients: A Retrospective Study. TRANSPLANTATION PROCEEDINGS. Jul-Aug 2019;51(6):1994-2001. doi: 10.1016/j.transproceed.2019.04.028.
IF: 0,959
Q: 4

Sambola A, Anguita M, Guzman G, Beltran P, Mila L, Gine M; Gender Differences in the Professional Lives of Cardiologists in 70 Spanish Hospitals. REVISTA ESPANOLA DE CARDIOLOGIA. (Engl Ed). 2019 Mar;72(3):272-274. doi: 10.1016/j.rec.2018.08.013. 
IF: 5,126
Q: 1 

Sambola A, Anguita M, Gine M; Is There a Gender Gap in Spanish Cardiology?. REVISTA ESPANOLA DE CARDIOLOGIA. (Engl Ed). 2019 Mar;72(3):195-197. doi: 10.1016/j.rec.2018.07.023.
IF: 5,126
Q: 1 

Amat-Santos IJ, Martin-Yuste V, Fernandez-Diaz JA, Martin-Moreiras J, Caballero-Borrego J, Salinas P, Ojeda S, Rivero F, Villota JN, Mohandes M, Dubois D, Ojeda FB, Rumiz E, Hernandez JMD, Jimenez-Mazuecos J, Lacunza J, Tejedor P, Gomez I, Goncalves-Ramir; Procedural, Functional and Prognostic Outcomes Following Recanalization of Coronary Chronic Total Occlusions. Results of the Iberian Registry. REVISTA ESPANOLA DE CARDIOLOGIA. (Engl Ed). 2019 May;72(5):373-382. doi: 10.1016/j.rec.2018.05.020.
IF: 5,126
Q: 1 

Saldivar HG, Alaminos LV, Rodriguez-Pascual C, de la Morena G, Fernandez-Golfin C, Amoros C, Alonso MB, Dolz LM, Sole AA, Guzman-Martinez G, Gomez-Doblas JJ, Jimenez AA, Fuentes ME, Gay LG, Ortiz MR, Avanzas P, Abu-Assi E, Ripoll-Vera T, Diaz-Castro O, Os; Prognosis of Patients With Severe Aortic Stenosis After the Decision to Perform an Intervention. REVISTA ESPANOLA DE CARDIOLOGIA. (Engl Ed). 2019 May;72(5):392-397. doi: 10.1016/j.rec.2018.03.023.
IF: 5,126
Q: 1 

Granero VCL, Santos SF, Fernandez-Golfin C, Gomez AG, Martin MP, Galarza JMD, Faletra FF, Swaans MJ, Lopez-Fernandez T, Mesa D, La Canna G, Garcia TE, Habib G, Monzonis AM, Gomez JLZ; Sustained Improvement of Left Ventricular Strain following Transcatheter Aortic Valve Replacement. CARDIOLOGY. 2019;143(1):52-61. doi: 10.1159/000500633.
IF: 1,561
Q: 4 

Vlastra W, Chandrasekhar J, Vendrik J, Gutierrez-Ibanes E, Tchetche D, de Brito FS, Barbanti M, Kornowski R, Latib A, D'Onofrio A, Ribichini F, Baan J, Tijssen JGP, Pan M, Dumonteil N, Mangione JA, Sartori S, D'Errigo P, Tarantini G, Lunardi M, Orvin K, P; Transfemoral TAVR in Nonagenarians From the CENTER Collaboration. JACC-CARDIOVASCULAR INTERVENTIONS. 2019 May 27;12(10):911-920. doi: 10.1016/j.jcin.2019.02.031.
IF: 9,544
D: 1 

Lekuona I, Anguita M, Zamorano JL, Rodriguez JM, de Soroa PB, Perez-Alcantara F; Would the Use of Edoxaban Be Cost-effective for the Prevention of Stroke and Systemic Embolism in Patients With Nonvalvular Atrial Fibrillation in Spain?. REVISTA ESPANOLA DE CARDIOLOGIA. (Engl Ed). 2019 May;72(5):398-406. doi: 10.1016/j.rec.2018.03.024.
IF: 5,126
Q: 1    

Azzalini L, Poletti E, Ayoub M, Ojeda S, Zivelonghi C, La Manna A, Bellini B, Lostalo A, Luque A, Venuti G, Montorfano M, Agostoni P, Pan M, Carlino M, Mashayekhi K. Coronary artery perforation during chronic total occlusion percutaneous coronary intervention: epidemiology, mechanisms, management, and outcomes. EUROINTERVENTION. 2019 Oct 4;15(9):e804-e811. doi: 10.4244/EIJ-D-19-00282.
IF: 4,018

Lopez-Fernandez T, Martin-Garcia A, Rabadan IR, Mitroi C, Ramos PM, Diez-Villanueva P, Cervantes CE, Martin CA, Salinas GLA, Arenas M, Esteban VIA, de la Pena FA, Fernandez AC, Pardo HG, Garcia-Sanz R, Porras JRG, de Sa EL, Lozano T, Vera PM, Marin VM, Ru. Atrial Fibrillation in Active Cancer Patients: Expert Position Paper and Recommendations. REVISTA ESPANOLA DE CARDIOLOGIA. (Engl Ed). 2019 Sep;72(9):749-759. doi: 10.1016/j.rec.2019.03.019.
IF: 5,126
Q: 1    

Regueiro A, Linke A, Latib A, Ihlemann N, Urena M, Walther T, Husser O, Herrmann HC, Nombela-Franco L, Cheema A, Le Breton H, Stortecky S, Kapadia S, Bartorelli AL, Sinning JM, Amat-Santos I, Munoz-Garcia AJ, Lerakis S, Gutierrez-Ibanes E, Abdel-Wahab M. Infective Endocarditis Following Transcatheter Aortic Valve Replacement Comparison of Balloon- Versus Self-Expandable Valves. CIRC CARDIOVASC INTERV. 2019 Nov;12(11):e007938. doi: 10.1161/CIRCINTERVENTIONS.119.007938. 
IF: 6.060

Gonzalez-Vilchez F, Almenar-Bonet L, Crespo-Leiro MG, Segovia-Cubero J, Gonzalez-Costello J, del Prado JMA, Sousa-Casasnovas I, Sobrino-Marquez JM, Delgado-Jimenez J, Perez-Villa F, Gomez-Buena M, Hernandez-Perez F, Martinez-Penades S, Cebrian-Pinar M, Lo. Spanish Heart Transplant Registry. 30th Official Report of the Spanish Society of Cardiology Working Group on Heart Failure (1984-2018). REVISTA ESPANOLA DE CARDIOLOGIA. (Engl Ed). 2019 Nov;72(11):954-962. doi: 10.1016/j.rec.2019.09.005. 
IF: 5,126
Q: 1    

Murga-Eizagaetxebarria N, Rodriguez-Padial L, Muniz J, Sambola A, Gomez-Doblas JJ, Pedreira M, Alonso-Martin JJ, Beltran P, Rodriguez-Roca G, Anguita M, Roig E. The Gender Perspective Within the OFRECE Study: Differences in Health Care Among Patients Consulting for Chest Pain and/or Palpitations. REVISTA ESPANOLA DE CARDIOLOGIA. (Engl Ed). 2019 Oct;72(10):813-819. doi: 10.1016/j.rec.2018.11.021.
IF: 5,126
Q: 1    

Main Publications 2018

Ramiro-Ortega E, Bonilla-Palomas JL, Gamez-Lopez AL, Moreno-Conde M, Lopez-Ibanez MC, Alhambra-Exposito R, Sanchez MA. Nutritional intervention in acute heart failure patients with undernutrition and normalbuminemia: A subgroup analysis of PICNIC study. CLINICAL NUTRITION. 2018; 37(5);1762-1764.
IF: 5,496  
Q: 1   D: 1

Ortiz MR, Muniz J, Miguez PR, Roldan I, Marin F, Esteve-Pastor MA, Cequier A, Martinez-Selles M, Bertomeu V, Anguita M. Inappropriate doses of direct oral anticoagulants in real-world clinical practice: prevalence and associated factors. A subanalysis of the FANTASIIA Registry. EUROPACE. 2018; 20(10):1577-1583.
IF: 5,231  
Q: 1

de Prado AP, Serrador A, Jimenez-Quevedo P, Gonzalez TB, Vazquez FF, Pan M. Selection of the Best of 2017 in Left Atrial Appendage Occlusion: Filling the Gap in Knowledge. REVISTA ESPANOLA DE CARDIOLOGIA. 2018; 71(3):225-227.
IF: 5,166  
Q: 1

Pan M, Ojeda S, Jimenez-Quevedo P, Serrador A, Azzalini L, de Prado AP. Selection of the Best of 2017 on Percutaneous Treatment of Chronic Occlusions. REVISTA ESPANOLA DE CARDIOLOGIA. 2018; 71(3):221-223.
IF: 5,166  
Q: 1

Ojeda S, Azzalini L, Chavarria J, Serra A, Hidalgo F, Benincasa S, Gheorghe LL, Diletti R, Romero M, Bellini B, Gutierrez A, de Lezo JS, Mazuelos F, Segura J, Carlino M, Colombo A, Pan M. One Versus 2-stent Strategy for the Treatment of Bifurcation Lesions in the Context of a Coronary Chronic Total Occlusion. A Multicenter Registry. REVISTA ESPANOLA DE CARDIOLOGIA. 2018; 71(6):432-439.
IF: 5,166  
Q: 1

Garzon FB, Alvarez-Ossorio MP, Moreno MAR, Palanco VM, Arroyo CH, Conde JSDC. Coronary Flow Reserve and Ventricular Function Following Regenerative Treatment in Patients With Revascularized Acute Anterior Myocardial Infarction. REVISTA ESPANOLA DE CARDIOLOGIA. 2018; 71(5):344-350.
IF: 5,166  
Q: 1

Hidalgo F, Castillo JC, Anguita M. Facts and details: Ivabradine in acute decompensated heart failure. INTERNATIONAL JOURNAL OF CARDIOLOGY. 2018; 270:202.
IF: 4,034  
Q: 2

Bonilla-Palomas JL, Gamez-Lopez AL, Castillo-Dominguez JC, Moreno-Conde M, Lopez-Ibanez MC, Anguita-Sanchez M. Does nutritional intervention maintain its prognostic benefit in the long term for malnourished patients hospitalised for heart failure?. REVISTA CLINICA ESPANOLA. 2018; 218(2):58-60.
IF: 1,184  
Q: 3

Montero-Perez FJ, Quero-Espinosa FB, Clemente-Millan MJ, Castro-Gimenez JA, de Burgos-Marin J, Romero-Moreno MA. Proposed clinical scale for the diagnosis of acute coronary syndrome in patients with an inconclusive electrocardiogram and myocardial injury biomarkers. REVISTA CLINICA ESPANOLA. 2018; 218(2):49-57.
IF: 1,184  
Q: 3

de Lezo JS, Martin P, Chavarria J. Acute coronary syndrome: an ideal scenario for direct Absorb implantation?. KARDIOLOGIA POLSKA. 2018; 76(10):1416-1417.
IF: 1,213  
Q: 4

Other Publications 2018

Bermejo J, Yotti R, Garcia-Orta R, Sanchez-Fernandez PL, Castano M, Segovia-Cubero J, Escribano-Subias P, San Roman JA, Borras X, Alonso-Gomez A, Botas J, Crespo-Leiro MG, Velasco S, Bayes-Genis A, Lopez A, Munoz-Aguilera R, de Teresa E, Gonzalez-Juanatey JR, Evangelista A, Mombiela T, Gonzalez-Mansilla A, Elizaga J, Martin-Moreiras J, Gonzalez-Santos JM, Moreno-Escobar E, Fernandez-Aviles F. Sildenafil for improving outcomes in patients with corrected valvular heart disease and persistent pulmonary hypertension: a multicenter, double-blind, randomized clinical trial. EUROPEAN HEART JOURNAL. 2018; 39(15):1255-1264.
IF: 23,425  
Q: 1   D: 1

Bermejo J, Yotti R, Fernandez-Aviles F. The elephant in the room: reply. EUROPEAN HEART JOURNAL. 2018; 39(36):3397-3397.
IF: 23,425  
Q: 1   D: 1

Ruiz JMM, Galderisi M, Buonauro A, Badano L, Aruta P, Swaans MJ, Sanchis L, Saraste A, Monaghan M, Theodoropoulos KC, Papitsas M, Liel-Cohen N, Kobal S, Bervar M, Berlot B, Filippatos G, Ikonomidis I, Katsanos S, Tanner FC, Cassani D, Faletra FF, Leo LA, Martinez A, Matabuena J, Grande-Trillo A, Alonso-Rodriguez D, Mesa D, Gonzalez-Alujas T, Sitges M, Carrasco-Chinchilla F, Li CH, Fernandez-Golfin C, Zamorano JL. Overview of mitral regurgitation in Europe: results from the European Registry of mitral regurgitation (EuMiClip). EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING. 2018; 19(5):503-507.
IF: 8,336 
Q: 1   D: 1

Alegre O, Formiga F, Lopez-Palop R, Marin F, Vidan MT, Martinez-Selles M, Carol A, Sionis A, Diez-Villanueva P, Aboal J, Palau-Vendrel A, Bueno H, Rivera AP, Sanchis J, Abu-Assi E, Corbi M, Castillo JC, Baneras J, Gonzalez-Salvado V, Cequier A, Ariza-Sole A. An Easy Assessment of Frailty at Baseline Independently Predicts Prognosis in Very Elderly Patients With Acute Coronary Syndromes. JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2018; 19(4):296-303.
IF: 5,325  
Q: 1   D: 1

Esteve-Pastor MA, Rivera-Caravaca JM, Roldan-Rabadan I, Roldan V, Muniz J, Rana-Miguez P, Ruiz-Ortiz M, Cequier A, Bertomeu-Martinez V, Badimon L, Anguita M, Lip GYH, Marin F. Relation of Renal Dysfunction to Quality of Anticoagulation Control in Patients with Atrial Fibrillation: The FANTASIIA Registry. THROMBOSIS AND HAEMOSTASIS. 2018; 118(2):279-287.
IF: 4,952  
Q: 1   D: 1

Esteve-Pastor MA, Rivera-Caravaca JM, Roldan-Rabadan I, Roldan V, Muniz J, Rana-Miguez P, Ruiz-Ortiz M, Cequier A, Bertomeu-Martinez V, Badimon L, Anguita M, Lip GYH, Marin F. Quality of oral anticoagulation with vitamin K antagonists in 'real-world' patients with atrial fibrillation: a report from the prospective multicentre FANTASIIA registry. EUROPACE. 2018; 20(9):1435-1441.
IF: 5,231  
Q: 1

Hernandez JMD, Rumoroso JR, Ojeda S, Brugaletta S, Cascon JD, Ruisanchez C, Gila JS, Roa J, Tizon H, Gutierrez H, Larman M, Camareroa TG, Pinar E, Diaz JF, Pan M, Bueno MM, Oyonarte JM, Guerrero LR, Ble M, Paton RR, Arnold R, Echegaray K, de la Morena G, Sabate M. Angina and Ischemia at 2 Years With Bioresorbable Vascular Scaffolds and Metallic Drug-eluting Stents. ESTROFA Ischemia BVS-mDES Study. REVISTA ESPANOLA DE CARDIOLOGIA. 2018; 71(5):327-334.
IF: 5,166  
Q: 1

Solana-Gracia R, Rueda F, Betrian P, Gutierrez-Larraya F, del Cerro MJ, Pan M, Alcibar J, Coserria JF, Velasco JM, Zunzunegui JL. Pediatrics Spanish Registry of Percutaneous Melody Pulmonary Valve Implantation in Patients Younger Than 18 Years. REVISTA ESPANOLA DE CARDIOLOGIA. 2018; 71(4):283-290.
IF: 5,166  
Q: 1

Vivas D, Roldan I, Ferrandis R, Marin F, Roldan V, Tello-Montoliu A, Ruiz-Nodar J, Gomez-Doblas J, Martin A, Llau J, Ramos-Gallo M, Munoz R, Arcelus J, Leyva F, Alberca F, Oliva R, Gomez A, Montero C, Arikans F, Ley L, Santos-Buesou E, Figuero E, Bujaldon A, Urbane J, Otero R, Hermida J, Egocheaga I, Llisterri J, Lobos J, Serrano A, Madridano O, Ferreiro J, Cassinello C, Gomez-Luque A, Hidalgo F, Sierra P, Vera P, Arranza J, Palomo V, Guerrero A, Anguita M, Iniguez A. Perioperative and Periprocedural Management of Antithrombotic Therapy: Consensus Document of SEC, SEDAR, SEACV, SECTCV, AEC, SECPRE, SEPD, SEGO, SEHH, SETH, SEMERGEN, SEMFYC, SEMG, SEMICYUC, SEMI, SEMES, SEPAR, SENEC, SEO, SEPA, SERVE', SECOT and AEU. REVISTA ESPANOLA DE CARDIOLOGIA. 2018; 71(7):553-564.
IF: 5,166  
Q: 1

Barreiro-Perez M, Li CH, Mesa D, Fernandez-Golfin C, Lopez-Fernandez T, de Isla LP. Selection of the Best of 2017 in Cardiac Imaging and Structural Interventionism. REVISTA ESPANOLA DE CARDIOLOGIA. 2018; 71(2):125-126.
IF: 5,166  
Q: 1

Jimenez-Quevedo P, Pan M, Serrador A, Gonzalo N, Del Trigo M, de Prado AP. Selection of the Best of 2017 in Interventional Cardiology: Revolution in the Study of Coronary Physiology and New Parameters. REVISTA ESPANOLA DE CARDIOLOGIA. 2018; 71(3):223-225.
IF: 5,166  
Q: 1

Toro R, Blasco-Turrion S, Morales-Ponce FJ, Gonzalez P, Martinez-Camblor P, Lopez-Granados A, Brugada R, Campuzano O, Perez-Serra A, Longobardo FR, Mangas A, Llorente-Cortes V, de Gonzalo-Calvo D. Plasma microRNAs as biomarkers for Lamin A/C-related dilated cardiomyopathy. JOURNAL OF MOLECULAR MEDICINE-JMM. 2018; 96(8):845-856.
IF: 4,938  
Q: 1

Rabadan IR, Esteve-Pastor MA, Anguita-Sanchez M, Muniz J, Siles JC, Quesada MA, Ortiz MR, Marin F, Selles MM, Bertomeu V, Lip GYH, Fillat AC, Badimon L. Relation of quality of anticoagulation control with different management systems among patients with atrial fibrillation: Data from FANTASIIA Registry. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 2018; 48(5): Núm artículo e12910
IF: 3,086  
Q: 1

Azzalini L, Ojeda S, Karatasakis A, Maeremans J, Tanabe M, La Manna A, Dautov R, Ybarra LF, Benincasa S, Bellini B, Candilio L, Demir OM, Hidalgo F, Karacsonyi J, Gravina G, Micciche E, D'Agosta G, Venuti G, Tamburino C, Pan M, Carlino M, Dens J, Brilakis ES, Colombo A, Rinfret S. Long-Term Outcomes of Percutaneous Coronary Intervention for Chronic Total Occlusion in Patients Who Have Undergone Coronary Artery Bypass Grafting vs Those Who Have Not. CANADIAN JOURNAL OF CARDIOLOGY. 2018; 34(3):310-318.
IF: 4,524  
Q: 2

Azzalini L, Ojeda S, Demir OM, Dens J, Tanabe M, La Manna A, Benincasa S, Bellini B, Poletti E, Maccagni D, Hidalgo F, Chavarria J, Maeremans J, Gravina G, Micciche E, D'Agosta G, Venuti G, Tamburino C, Pan M, Carlino M, Colombo A. Recanalization of Chronic Total Occlusions in Patients With vs Without Chronic Kidney Disease: The Impact of Contrast-Induced Acute Kidney Injury. CANADIAN JOURNAL OF CARDIOLOGY. 2018; 34(10):1275-1282.
IF: 4,524  
Q: 2

Mintz GS, Lefevre T, Lassen JF, Testa L, Pan M, Singh J, Stankovic G, Banning AP. Intravascular ultrasound in the evaluation and treatment of left main coronary artery disease: a consensus statement from the European Bifurcation Club. EUROINTERVENTION. 2018; 14(4):E467-E474.
IF: 4,417  
Q: 2

Lassen JF, Burzotta F, Banning AP, Lefevre T, Darremont O, Hildick-Smith D, Chieffo A, Pan M, Holm NR, Louvard Y, Stankovic G. Percutaneous coronary intervention for the left main stem and other bifurcation lesions: 12th consensus document from the European Bifurcation Club. EUROINTERVENTION. 2018; 13(13):1540-1553.
IF: 4,417  
Q: 2

Burzotta F, Lassen JF, Banning AP, Lefevre T, Hildick-Smith D, Chieffo A, Darremont O, Pan M, Chatzizisis YS, Albiero R, Louvard Y, Stankovic G. Percutaneous coronary intervention in left main coronary artery disease: the 13th consensus document from the European Bifurcation Club. EUROINTERVENTION. 2018; 4(1):112-120.
IF: 4,417  
Q: 2

Azzalini L, Demir OM, Gasparini AL, Grancini L, La Manna A, Ojeda S, Benincasa S, Bellini B, Poletti E, Maccagni D, Soldi M, Lannetta L, Trabattoni D, Gravina G, Hidalgo F, Giannini F, Pan M, Tamburino C, Bartorelli AL, Reimers B, Godino C, Carlino M, Colombo A. Outcomes of a novel thin-strut bioresorbable-polymer sirolimus-eluting stent in patients with chronic total occlusions: A multicenter registry. INTERNATIONAL JOURNAL OF CARDIOLOGY. 2018; 258:36-41.
IF: 4,034  
Q: 2

Barge-Caballero E, Almenar-Bonet L, Crespo-Leiro MG, Brossa-Loidi V, Rangel-Sousa D, Gomez-Bueno M, Farrero-Torres M, Diaz-Molina B, Delgado-Jimenez J, Martinez-Selles M, Lopez-Granados A, De-la-Fuente-Galan L, Gonzalez-Costello J, Garrido-Bravo IP, Blasco-Peiro T, Rabago-Juan-Aracil G, Gonzalez-Vilchez F. Preoperative Toxoplasma gondii serostatus does not affect long-term survival of cardiac transplant recipients. Analysis of the Spanish Heart Transplantation Registry. INTERNATIONAL JOURNAL OF CARDIOLOGY. 2018; 250:183-187.
IF: 4,034  
Q: 2

Mates J, Mademont-Soler I, del Olmo B, Ferrer-Costa C, Coll M, Perez-Serra A, Pico F, Allegue C, Fernandez-Falgueras A, Alvarez P, Yotti R, Espinosa MA, Sarquella-Brugada G, Cesar S, Carro E, Brugada J, Arbelo E, Garcia-Pavia P, Borregan M, Tizzano E, Lopez-Granados A, Mazuelos F, de Bustamante AD, Darnaude MT, Gonzalez-Hevia JI, Diaz-Flores F, Trujillo F, Iglesias A, Fernandez-Aviles F, Campuzano O, Brugada R. Role of copy number variants in sudden cardiac death and related diseases: genetic analysis and translation into clinical practice. EUROPEAN JOURNAL OF HUMAN GENETICS. 2018; 26(7):1014-1025.
IF: 3,636  
Q: 2

Azzalini L, Candilio L, Ojeda S, Dens J, La Manna A, Benincasa S, Bellini B, Hidalgo F, Chavarria J, Maeremans J, Gravina G, Micciche E, D'Agosta G, Venuti G, Tamburino C, Pan M, Carlino M, Colombo A. Impact of Incomplete Revascularization on Long-Term Outcomes Following Chronic Total Occlusion Percutaneous Coronary Intervention. AMERICAN JOURNAL OF CARDIOLOGY. 2018; 121(10):1138-1148.
IF: 3,171  
Q: 2

Azzalini L, Karatasakis A, Spratt JC, Tajti P, Riley RF, Ybarra LF, Schumacher SP, Benincasa S, Bellini B, Candilio L, Mitomo S, Henriksen P, Hidalgo F, Timmers L, Kraaijeveld AO, Agostoni P, Roy J, Ramsay DR, Weaver JC, Knaapen P, Nap A, Starcevic B, Ojeda S, Pan M, Alaswad K, Lombardi WL, Carlino M, Brilakis ES, Colombo A, Rinfret S, Mashayekhi K. Subadventitial stenting around occluded stents: A bailout technique to recanalize in-stent chronic total occlusions. CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS. 2018; 92(3):466-476.
IF: 2,602  
Q: 2

Granero VCL, Santos SF, Fernandez-Golfin C, Martin MP, Galarza JMD, Faletra FF, Swaans MJ, Lopez-Fernandez T, Mesa D, La Canna G, Garcia TE, Habib G, Monzonis AM, Gomez JLZ. Immediate improvement of left ventricular mechanics following transcatheter aortic valve replacement. CARDIOLOGY JOURNAL. 2018; 25(4):487-494.
IF: 1,339  
Q: 4

Gutierrez-Barrios A, Ojeda S, Pan M, Alba M, Agarrado A, Oneto J. Dual-lumen catheter in coronary chronic occlusions. COR ET VASA. 2018; 60(5):E482-E486.
IF: 0

Main Publications 2017

Pan M, Ojeda S, Villanueva E, Romero M. REPLY: No Wire Fracture Is Great News, But Is Polymer Shearing the Real Danger? JACC-CARDIOVASCULAR INTERVENTIONS. 2017.10(2):204-204.
IF: 8,841
Q: 1  D: 1

Estevez-Loureiro R, Freixa X, Arzamendi D, de Prado AP, Campante-Teles R, Melica B, Tarantini G, Musumeci G, Pan M. Transcatheter mitral valve interventions for mitral regurgitation, with special focus on MitraClip: The position of Spanish, Portuguese and Italian interventional societies. INTERNATIONAL JOURNAL OF CARDIOLOGY. 2017.243():169-173.
IF: 6,189
Q: 1 

Ojeda S, Pan M, Gutierrez A, Romero M, Chavarria J, de Lezo JS, Mazuelos F, Pardo L, Hidalgo F, Carrasco F, Segura J, Duran E, Ferreiro C, Sanchez JJ, Rodriguez S, Oneto J, de Lezo JS. Bifurcation lesions involved in the recanalization process of coronary chronic total occlusions: Incidence, treatment and clinical implications. INTERNATIONAL JOURNAL OF CARDIOLOGY. 2017.230():432-438.
IF: 6,189
Q: 1 

Hidalgo FJ, Anguita M. Ivabradine in acute decompensated systolic heart failure. INTERNATIONAL JOURNAL OF CARDIOLOGY. 2017.235():198-198.
IF: 6,189
Q: 1 

Pan M, Albiero R, Banning A, Burzotta F, Chatzizisis YS, Chieffo A, Darrcmont O, Ferenc M, Hildick-Smith D, Lassen JF, Lefevre T, Louvard Y, Stankovic G, European Bifurcartion Club Comm. In memoriam Alfonso Medina Fernandez-Aceituno, MD, 1946-2017. EUROINTERVENTION.2017.13(3):269-269.
IF: 5,165
Q: 1 

Carrasco F, Castillo JC, Ruiz M, Anguita M. Comments on clinical features and changes in epidemiology of infective endocarditis on pacemaker devices over a 27-year period (1987-2013): reply. EUROPACE. 2017.19(4):695-696.
IF: 4,53
Q: 1 

Anguita M, Lambert JL, Segovia J.SEC-Excellence Comm Heart FailureHeart Failure Programs / Units. A Multidisciplinary Approach Response.REVISTA ESPANOLA DE CARDIOLOGIA. 2017.70(5):411-411.
IF: 4,485
Q: 1 

Jimenez-Quevedo P, Serrador A, de Prado AP, Nombela-Franco L, Biagioni C, Pan M. Selection of the Best of 2016 in Interventional Cardiology: Expansion of TAVI Indications to Intermediate-risk Patients. REVISTA ESPANOLA DE CARDIOLOGIA. 2017.70(3):218-219.
IF: 4,485
Q: 1 

Pan M, Jimenez-Quevedo P, Serrador A, de Prado AP, Mesa D, Loureiro RE. Selection of the Best of 2016 in MitraClip Therapy for the Treatment of Functional Mitral Regurgitation. REVISTA ESPANOLA DE CARDIOLOGIA. 2017.70(3):216-218.
IF: 4,485
Q: 1 

Montoro LC, Rabadan IR, Ortuno FM, Martinez VB, Garcia JM, Sanchez MA, Investigadores Estudio FANTASIIA. Differences in the Characteristics and Management of Patients With Atrial Fibrillation Followed-up by Cardiologists and Other Specialists. REVISTA ESPANOLA DE CARDIOLOGIA. 2017.70(10):883-886.
IF: 4,485
Q: 2 

Chavarria J, de Lezo JS, Ojeda S, Pan M, Segura J, Mazuelos F, Espejo S, Lopez J, Romero M, de Lezo JS. Restenosis After Everolimus-eluting Vascular Scaffolding. Angiographic and Optical Coherence Tomography Characterization. REVISTA ESPANOLA DE CARDIOLOGIA. 2017.70(7):543-550.
IF: 4,485
Q: 2 

Sanchez MA, Dominguez JCC. Do All Patients With Heart Failure Benefit From a Program for Early Follow-up After Hospital Discharge? REVISTA ESPANOLA DE CARDIOLOGIA. 2017.70(8):624-625.
IF: 4,485
Q: 2 

Carrasco-Chinchilla F, Estevez-Loureiro R, Andraka L, Arzamendi D, Freixa X, de Lezo JS. Percutaneous Mitral Repair With MitraClip in Patients Treated With Transcatheter Aortic Valve Implantation. REVISTA ESPANOLA DE CARDIOLOGIA. 2017.70(12):1144-1145.
IF: 4,485
Q: 2 

Frutos AMS, Jimenez-Quevedo P, de Prado AP, Alvarez-Ossorio MP. Spanish Cardiac Catheterization and Coronary Intervention Registry. 26th Official Report of the Spanish Society of Cardiology Working Group on Cardiac Catheterization and Interventional Cardiology (1990-2016).REVISTA ESPANOLA DE CARDIOLOGIA. 2017.70(12):1110-1120.
IF: 4,485
Q: 2 

Hidalgo FJ, Anguita M. Role of Ivabradine in the Treatment of Heart Failure: Comments on the ESC 2016 Guidelines. REVISTA ESPANOLA DE CARDIOLOGIA. 2017.70(7):612-613.
IF: 4,485
Q: 2 

Gamez JM, Masmiquel L, Ripoll T, Barrios V, Anguita M, SIRENA Study. Diabetes mellitus and cardiovascular clinical characteristics of Spanish women with stable ischaemic heart disease: Data from the SIRENA study. DIABETES RESEARCH AND CLINICAL PRACTICE. 2017.123():82-86.
IF: 3,639
Q: 2 

Carmona MD, Canadillas S, Romero M, Blanco A, Nogueras S, Herrera C. Intramyocardial bone marrow mononuclear cells versus bone marrow-derived and adipose mesenchymal cells in a rat model of dilated cardiomyopathy. CYTOTHERAPY. 2017.19(8):947-961.
IF: 3,203
Q: 2 

Pardo Gonzalez L, Ruiz Ortiz M, Delgado M, Mesa D, Villalba R, Rodriguez S, Hidalgo FJ, Alados P, Casares J, Suarez de Lezo J. Pulmonary homograft stenosis in the Ross procedure: Incidence, clinical impact and predictors in long-term follow-up. ARCHIVES OF CARDIOVASCULAR DISEASES. 2017.110(4):214-222.
IF: 2,331
Q: 2 

Castillo F, Castillo JC, Anguita P, Roldan R, Gamez P, Anguita M. Do we follow recommendations on infective endocarditis prophylaxis? Differences between the health professionals involved. ATENCION PRIMARIA. 2017.49(3):198-200.
IF: 1,042
Q: 3 

Anguita P, Castillo F, Gamez P, Carrasco F, Roldan R, Jurado B, Castillo JC, Martin E, Anguita M. Behaviour of health professionals concerning the recommendations for prophylaxis for infectious endocarditis in our setting: Are the guidelines followed? REVISTA CLINICA ESPANOLA. 2017.217(2):79-86.
IF: 0,971
Q: 3 

Avalos FC, Lesmes FJH, Ortiz MR, Sanchez MA. Early prosthetic valve infective endocarditis in the elderly: Changes over a 28-year period (1987-2014). REVISTA CLINICA ESPANOLA. 2017.217(3):174-176.
IF: 0,971
Q: 3 

Anguita M. High-sensitivity troponins and prognosis of heart failure. REVISTA CLINICA ESPANOLA. 2017.217(2):95-96.
IF: 0,971
Q: 3 

Montero-Perez FJ, Quero-Espinosa FD, Clemente-Millan MJ, Castro-Gimenez JA, de Burgos-Marin J, Romero-Moreno MA. Diagnostic validity of hand gestures in chest pain of coronary origin. REVISTA CLINICA ESPANOLA. 2017.217(5):252-259.
IF: 0,971
Q: 3 

Other Publications 2017

Amat-Santos IJ, Cortes C, Franco LN, Munoz-Garcia AJ, De Lezo JS, Gutierrez-Ibanes E, Serra V, Larman M, Moreno R, Hernandez JMD, Puri R, Jimenez-Quevedo P, Garcia JMH, Alonso-Briales JH, Garcia B, Lee DH, Rojas P, Sevilla T, Goncalves R, Vera S, Gomez I, Rodes-Cabau J, San Roman JA. Prosthetic Mitral Surgical Valve in Transcatheter Aortic Valve Replacement Recipients A Multicenter Analysis. JACC-CARDIOVASCULAR INTERVENTIONS. 2017.10(19):1973-1981.
IF: 8,841
Q: 1  D: 1

Azzalini L, Dautov R, Ojeda S, Benincasa S, Bellini B, Giannini F, Chavarra J, Pan M, Carlino M, Colombo A, Rinfret S. Procedural and Long-Term Outcomes of Percutaneous Coronary Intervention for In-Stent Chronic Total Occlusion. JACC-CARDIOVASCULAR INTERVENTIONS. 2017.10(9):892-902.
IF: 8,841
Q: 1  D: 1

Azzalini L, Dautov R, Brilakis ES, Ojeda S, Benincasa S, Bellini B, Karatasakis A, Chavarria J, Rangan BV, Pan M, Carlino M, Colombo A, Rinfret S. Procedural and longer-term outcomes of wire- versus device-based antegrade dissection and re-entry techniques for the percutaneous revascularization of coronary chronic total occlusions. INTERNATIONAL JOURNAL OF CARDIOLOGY. 2017.231():78-83.
IF: 6,189
Q: 1 

Azzalini L, Dautov R, Brilakis ES, Ojeda S, Benincasa S, Bellini B, Karatasakis A, Chavarria J, Rangan BV, Pan M, Carlino M, Colombo A, Rinfret S. Impact of crossing strategy on midterm outcomes following percutaneous revascularisation of coronary chronic total occlusions. EUROINTERVENTION. 2017.13(8):978-985.
IF: 5,193
Q: 1 

Hernandez JMD, Rumoroso JR, Subinas A, Gonzalo N, Ojeda S, Pan M, Yuste VM, Suarez A, Herandez F, Teruel L, Moreu J, Cubero JM, Cascon JD, Vinhas H, Lozano I, Moreiras JM, de Prado AP, Goicolea J, Escaned J. Percutaneous intervention in chronic total coronary occlusions caused by in-stent restenosis: procedural results and long-term clinical outcomes in the TORO (Spanish registry of chronic TOtal occlusion secondary to an occlusive in-stent RestenOsis) multicentre registry. EUROINTERVENTION. 2017.13(2):E219-E226.
IF: 5,193
Q: 1 

Fam JM, Ojeda S, Garbo R, Latib A, La Manna A, Vaquerizo B, Boukhris M, Vlachojannis GJ, van Geuns RJ, Ezhumalai B, Kawamoto H, van der Sijde J, Felix C, Pan M, Serdoz R, Boccuzzi GG, De Paolis M, Sardella G, Mancone M, Tamburino C, Smits PC, Di Mario C, Seth A, Serra A, Colombo A, Serruys P, Galassi AR, Zijlstra F, Van Mieghem NM, Diletti R. Everolimus-eluting bioresorbable vascular scaffolds for treatment of complex chronic total occlusions. EUROINTERVENTION. 2017.13(3):355-363.
IF: 5,165
Q: 1 

Loughlin G, Avila P, Martinez-Ferrer JB, Alzueta J, Vinolas X, Brugada J, Arizon JM, Fernandez-Lozano I, Garcia-Campo E, Basterra N, De La Concha JF, Arenal A. Association of cardiac resynchronization therapy with the incidence of appropriate implantable cardiac defibrillator therapies in ischaemic and non-ischaemic cardiomyopathy. EUROPACE. 2017.19(11):1818-1825.
IF: 4,521
Q: 1 

Avanzas P, Pascual I, Munoz-Garcia AJ, Segura J, Alonso-Briales JH, de Lezo JS, Pan M, Jimenez-Navarro MF, Lopez-Aguilera J, Hernandez-Garcia JM, Moris C. Long-term Follow-up of Patients With Severe Aortic Stenosis Treated With a Self-expanding Prosthesis. REVISTA ESPANOLA DE CARDIOLOGIA. 2017.70(4):247-253.
IF: 4,485
Q: 1 

Arribas F1, SEC Working Group for the 2016 ESC Guidelines for the Management of Atrial Fibrillation: Arribas F, Roldán I, Luis Merino J, Roldán V, Arenal Ÿ, Tamargo J, Ruiz-Granell R, Mont L, Anguita M, Marín F; Reviewers for the 2016 ESC Guidelines for the Management of Atrial Fibrillation:, Barrios Alonso V, Barón G, Esquivias, Cosín Sales J, Díaz Infante E, Escobar Cervantes C, Ferreiro Gutiérrez JL, Guerra Ramos JM, Jiménez Candil FJ, Pérez Castellano N, Sambola Ayala A, Tello Montoliu A; SEC Guidelines Committee:, San Román A, Alfonso F, Arribas F, Evangelista A, Ferreira I, Jiménez M, Marín F, de Isla LP, Rodríguez Padial L, Sánchez PL, Sionis A, Vázquez R. Comments on the 2016 ESC Guidelines for the Management of Atrial Fibrillation. REVISTA ESPANOLA DE CARDIOLOGIA. 2017.70(1):2-8.
IF: 4,485
Q: 2 

Romo AI, Martinez VB, Padial LR, Sanchez MA, Mateas FR, Urbano RH, Sobrino JLB, Perez CF, de Miguel CM, Somoza FJE. The RECALCAR Project. Healthcare in the Cardiology Units of the Spanish National Health System, 2011 to 2014. REVISTA ESPANOLA DE CARDIOLOGIA. 2017.70(7):567-575.
IF: 4,485
Q: 2 

Gonzalez-Vilchez F, Gomez-Bueno M, Almenar-Bonet L, Crespo-Leiro MG, del Prado JMA, Delgado-Jimenez J, Sousa-Casasnovas I, Brossa-Loidi V, Sobrino-Marquez JM, Gonzalez-Costelo J, Equipos Espanoles Trasplante Cardi. Spanish Heart Transplant Registry. 28th Official Report of the Spanish Society of Cardiology Working Group on Heart Failure (1984-2016). REVISTA ESPANOLA DE CARDIOLOGIA. 2017.70(12):1098-1109.
IF: 4,485
Q: 2 

Marin F, Anguita-Sanchez M, Sanmartin M. Direct oral anticoagulants and cardiovascular prevention in patients with nonvalvular atrial fibrillation. EXPERT OPINION ON PHARMACOTHERAPY. 2017.18(1):67-77.
IF: 3,894
Q: 1 

Rivera-Caravaca JM, Marin F, Esteve-Pastor MA, Rana-Miguez P, Anguita M, Muniz J, Cequier A, Bertomeu-Martinez V, Valdes M, Vicente V, Lip GYH, Roldan V. Usefulness of the 2MACE Score to Predicts Adverse Cardiovascular Events in Patients With Atrial Fibrillation. AMERICAN JOURNAL OF CARDIOLOGY. 2017.120(12):2176-2181.
IF: 3,398
Q: 2 

Azzalini L, Dautov R, Ojeda S, Serra A, Benincasa S, Bellini B, Giannini F, Chavarria J, Gheorghe LL, Pan M, Carlino M, Colombo A, Rinfret S. Long-term Outcomes of Rotational Atherectomy for the Percutaneous Treatment of Chronic Total Occlusions. CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS. 2017.89(5):820-828.
IF: 2,602
Q: 2 

Ruiz JMM, Fernandez-Golfin C, Mesa D, Gonzalez-Alujas T, Sitges M, Carrasco-Chinchilla F, Li CH, Grande-Trillo A, Martinez A, Matabuena J, Alonso-Rodriguez D, Aquila I, Zamorano JL. Prevalence of optimal valve morphology for MitraClip in patients with mitral regurgitation. ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES. 2017.34(8):1122-1129.
IF: 1,314
Q: 4 

Pose A, Almenar L, Manzano L, Gavira JJ, Granados AL, Delgado J, Aramburu O, Arevalo JC, Mendez M, Comin J, Manito N. Hyponatraemia and congestive heart failure refractory to diuretic treatment. Utility of tolvaptan. REVISTA CLINICA ESPANOLA. 2017.217(7):398-404.
IF: 0,971
Q: 3      

Clinical Research

Active in 2019

Ensayo clinico fase III, unicéntrico, abierto, controlado y aleatorizado, para valorar la eficacia de la infusión intracoronaria de células mononucleadas de médula ósea autóloga en pacientes con oclusión coronaria crónica y disfunción ventricular previame.
PI: Dr. Manuel Pan Álvarez-Ossorio

Prevención secundaria de la Enfermedad Cardiovascular em Ancianos (SECURE).
PI: Dr. Miguel Ángel Romero Moreno

Estudio en Fase III, aleatorizado, doble ciego y controlado con placebopara evaluar los efectos de dalcetrapib sobre el riesgo cardiovascular (CV) en una población definida genéticamente con síndrome coronario agudo reciente (SCA): el ensayo dal-genE.
PI: Dr. Djordje Pavlovic Djurovic

Estudio doble ciego, aleatorizado, controlado con placebo, multicentrico para evaluar la eficiacia de Omecamtiv y  mecarbil en la mortalidad y morbilidad de sujetos con insuficiencia cardiaca cronica conf raccion de eyeccion reducida.
PI: Dr. José María Arizon Del Prado

An Open-label, 2 x 2 Factorial, Randomized controlled, clinical trial to evaluate the safety of apixaban vs Vitamin K antagonist and Aspirin Placebo in Patients with Atrial Fibrillation and Acute Coronary Syndrome or Percutaneous Coronary Intervention.
PI: Dr. Djordje Pavlovic Djurovic

Estrategia antitrombótica para reducir las complicaciones cardiovasculares, neurológicas y hemorrágicas tras una implantación valvular aórtica por vía percutánea: Estudio ATLANTIS.
PI: Dr. Manuel Pan Álvarez-Ossorio

Tratamiento con betabloqueantes tras infarto de miocardio sin fraccion de eyeccion reducida.
PI: Dr. Manuel Anguita Sánchez

Estudio de fase 3, multinacional, aleatorizado y controlado con placebo de ARRY-371797 en pacientes con miocardiopatía dilatada sintomática por mutación del gen lamina A/C.
PI: Dr. Juan Carlos Castillo Dominguez

Estudio europeo de bifurcaciones coronarias: comparación aleatorizada de una estrategia de stent provisional frente a la implantación sitemática de dos stents, en bifurcaciones verdaderas localizadas en vasos grandes. 
PI: Dr. Manuel Pan Álvarez-Ossorio

Global review of long-term oral antithrombotic therapy in patients with atrial fibrillation (Phase II/III EU/ESA Member States).
PI: Dr. Amador López Granados

International registry to assess medical practice with longitudinal observation for treatment of heart failure.
PI: Dr. Arizon Del Prado, José María

EBC MAIN: Study conducted by the European Bifurcation Club: randomized comparison of the implementation of one or two stents to treat bifurcation lesions of the common trunk of the left coronary artery.
PI: Dr. Manuel Pan Álvarez-Ossorio

Registro de hipersolesterolemia familiar en el síndrome coronario agudo.
PI: Dr. Manuel Anguita Sánchez

Multicenter Registry of Secondary Revascularization.
PI: Dr. Soledad Ojeda Pineda

Second-generation drUg-eluting stents in diabetes: a Randomized trial (the SUGAR trial).
PI: Dr. Miguel Ángel Romero Moreno

Factores de riesgo asociados con la progresión de la insuficiencia cardiaca en pacientes con fibrilación auricular tratados con anticoagulante oral directo.
PI: Dr. Amador López Granados

Registro Observacional Prospectivo de Pacientes con Insuficiencia Cardíaca.
PI: Dr. Juan Carlos Castillo Dominguez

Concordancia entre ffr e ifr para valoracion de lesiones intermediass en el tronco comun izquierdo. aplicacion prospectiva de un valor ifr predefinido para la valoracion de lesiones intermedias en el tronco comun izquierdo estudio ilitro. 
PI: Dr. Soledad Ojeda Pineda

Safety and efficacy of the tricvalve transcatherter bicaval valves system in the superior and inferior vana cava in patients with severe tricuspid regurgitation. 
PI: Dr. Manuel Pan Álvarez-Ossorio

Members

Dr. Manuel Pan Álvarez-Ossorio

Principal Investigator

Team

Manuel Pablo Anguita Sanchez José Mª Arizón del Prado Juan Carlos Castillo Domínguez Mónica Mª Delgado Ortega Amador López Granados Francisco Mazuelos Bellido Mª Dolores Mesa Rubio Soledad Ojeda Pineda Djordje Pavlovic Miguel Ángel Romero Moreno Martín Ruíz Ortíz José Mª Segura Saint-Gerons Javier Suárez de Lezo Herreros de Tejada José López Aguilera Aurora Luque Moreno Francisco José Hidalgo Lesmes Eva Cebrián Salgado