The general objective of our programme is to generate new knowledge in the fields of nutrition, metabolic diseases and neuroendocrinology with a view to preventing and improving the management of health disorders related to each of these areas. The world is currently witnessing an epidemic of nutrition-related diseases, particularly metabolic syndromes associated with obesity. Despite active research and the important advances that have been made, we still do not know the exact causes or underlying mechanisms of these diseases or how to effectively prevent and treat them. Given that these processes are closely linked to life expectancy, quality of life, well-being and the sustainability of the National Health System, their study is of crucial importance. Moreover, the intraindividual behavioural variability of people who live in the same environment is related to varying degrees of disease susceptibility and severity.
Certain factors that contribute to susceptibility are already known or suspected, such as the genetic substrate, epigenetic components and the mechanisms involved in the neuroendocrine regulation of appetite, in addition to molecular biological mechanisms, such as oxidative stress, inflammation or hypoxia response. For this reason, a key objective of our programme is to conduct research based on a multidisciplinary approach to the concept of precision medicine. By integrating clinical and molecular information, we can identify the qualities that make each individual unique and will be able to provide personalized medicine in the future. This is especially important in the management of diabetes and neuroendocrine tumours, which are key objectives of our programme. A further priority of our scientific activity and effort is to foster synergies, promote talent and employability in the National Health System and accelerate the transfer and translationality of our research findings, thus contributing to the creation of wealth.
- Metabolic syndrome
- Reproductive health
- Paediatric and perinatal diseases
- Neuroendocrine tumours