Research Groups

Nutrigenomics Metabolic Syndrome

Scientific Production and Human Team

Principal Investigator

Dr. José López Miranda

CIBER on Obesity and Nutrition (CIBERobn)

PAIDI CTS-525 scientific Group

Co-Principal Investigator

Dr. Francisco Pérez Jiménez

PAIDI CTS-212 scientific Group

Co-Principal Investigator

Dr. Javier Delgado Lista

Co-Principal Investigator

Dr. Pablo Pérez Martínez

Co-Principal Investigator

Dra. Yolanda Almadén Peña

Nutrigenomics Metabolic Syndrome

Scientific Activity

Our group studies the effect of dietary components on cardiovascular risk from a dual approach: nutrigenetics and their biological action on factors and mechanisms related to the development of atherosclerosis, preferably in patients with metabolic syndrome. Through nutrigenetics, we investigate how common genetic variants modulate the influence of diet on markers such as postprandial metabolism, endothelial function, obesity or glucose metabolism. While investigating their biological effects, we analyze the action of nutrients on atherogenic mechanisms such as oxidative stress, inflammation, endothelial function, hemostasis, cellular signalling mechanisms and the activation of genes involved in atherogenesis.

Keywords

Atherosclerosis, metabolic syndrome, Mediterranean diet, endothelium, inflammation, oxidative stress, cholesterol, polyphenols, gene expression, proteomics, nutrigenetics, nutrigenomics