Detalle de la oferta


The GROUP: GC-06 "Nuevas terapias en cáncer" Look for CANDIDATES to apply to MINECO Program "Sara Borrell" (2016)

Place: Maimonides Biomedical Research Institute of Cordoba (IMIBIC)

Link of Group:



Se valorará

- PhD obtained after 1st January 2012 Evaluation: 

- Candidate CV: 50 points (publications on peer-reviewed journals are required) 

- Research Project: 15 points - Research Group: 35 points

Documentación a presentar


La presente convocatoria se publicará en los tablones de anuncios de FIBICO, así como en las páginas web siguientes:

- En la del Hospital Universitario Reina Sofía de Córdoba.

- En la del IMIBIC (

- En Euraxess.

Perfil del solicitante

The group is interested in the development of reliable clinical biomarkers to help predict which patients will respond to targeted therapies in cancer. The studies carried out are aimed to establish the mechanisms involved in the de novo or secondary resistance to these treatments, and to identify predictor biomarkers of response to therapy. One line of research is one addressed to study the role of nitric oxide (NO) and nitrosative stress in cancer. Induced NO modifications such as protein nitrosylation, can be a key regulatory factor, both in tumorigenesis and tumor progression and anti-tumor therapy. In fact, the emerging role of the nitrosylation of proteins in tumor biology, including its participation in regulatory epigenetic mechanisms also extends to routes of specific cell signaling in cancer stem cells, or fundamental processes of progression tumor as angiogenesis. Therefore, the dissection of these interconnections may provide prognostic markers and response to treatment in colon, breast cancer and other neoplastic pathologies, and to identify new therapeutic approaches. This line of research is funded by several research projects granted in both regional and national public calls. During the last years, the group has broadened and consolidated its capacity to implement innovative technologies in the study of cellular and molecular oncology, through the incorporation of novel methodologies, including liquid biopsy and also preclinic experimental models.


Solicitud, lugar y plazo de presentación

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